Results 41 to 50 of about 1,132,887 (301)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective There is a lack of studies on seizure outcomes associated with ofatumumab therapy in patients for relapsing anti‐N‐methyl‐D‐aspartate (NMDA) receptor encephalitis. We aimed to evaluate long‐term seizure outcomes of ofatumumab therapy for relapsing anti‐NMDA receptor encephalitis.
Jian Wang, Mengjiao Li, Ping Kong
wiley +1 more source
, 2018 Patients are often admitted to the neurosciences intensive care unit specifically for the treatment of a series of seizures or focal status epilepticus. Far more urgent is convulsive status epilepticus, which requires multiple intravenously administered ...
Sarah L. Clark, Eelco F. M. Wijdicks
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Rational Polytherapy with Antiepileptic Drugs
Pharmaceuticals, 2010 Approximately 30–40% of patients do not achieve seizure control with a single antiepileptic drug (AED). With the advent of multiple AEDs in the past 15 years, rational polytherapy, the goal of finding combinations of AEDs that have favorable ...
Jong Woo Lee, Barbara Dworetzky
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Advanced Science, EarlyView.ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee +3 more
wiley +1 more source
Epilepsy, Pregnancy, and Antiepileptic Drugs
Archives of Epilepsy, 2018 Pregnancy follow-up is different in epilepsy patients in comparison with healthy individuals. The rate of maternal and infant mortality, as well as pregnancy and delivery complications, is greater than in the normal population.
Betül TEKİN
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Antiepileptic drugs in pediatric epilepsy
Journal of Pediatric Neurosciences, 2008 The epilepsies are socially handicapping disorders and even a single seizure occurring in certain circumstances may have disastrous effect. The impact of epilepsy on every aspect of both the lives of the child and family is significant.
Sangeeta H Ravat, Rohit Gupta
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Antiepileptic drugs and breastfeeding [PDF]
Italian Journal of Pediatrics, 2013 Abstract Introduction This review provides a synopsis for clinicians on the use of antiepileptic drugs (AEDs) in the breastfeeding mother. Methods For each AED, we collected all retrievable data from Hale’s “Medications and Mother Milk” (2012), from the LactMed database ...
Davanzo, Riccardo +5 more
openaire +2 more sources
Lactylation‐Mediated HER2 Stabilization Promotes Trastuzumab Resistance in Gastric Cancer
Advanced Science, EarlyView.Warburg effect‐derived lactate drives HER2 lactylation and trastuzumab resistance. Mechanistically, AARS1‐mediated lactylation stabilizes HER2 by inhibiting USP11‐dependent degradation and concurrently promotes HER2‐EGFR interaction. Importantly, inhibiting HER2 lactylation resensitizes gastric cancer cells to trastuzumab.
Meng Qian +11 more
wiley +1 more source
Antiepileptic drugs in psychiatry [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 2004 The potential risks of AEDs widely used in psychiatric patients are not fully understood Antiepileptic drugs (AEDs) have been widely used by psychiatrists to treat disorders other than epilepsy for two decades. Here I survey those uses and selectively review the side effects of AEDs in the psychiatric context.
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Genetic and Immune Predictors for Hypersensitivity Syndrome to Antiepileptic Drugs [PDF]
, 2011 Hypersensitivity syndrome reactions (HSR) to antiepileptic drugs (AED) are associated with severe clinical cutaneous adverse reactions (SCAR).Our aims are: to assess HSRs to AEDs using the in vitro lymphocyte toxicity assay (LTA) in patients who ...
Lawrence Cohen +3 more
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