Results 21 to 30 of about 75,779 (301)
Established antiepileptic drugs
Seizure, 1997 Despite the recent entry into the market-place of a range of new pharmacological treatments for epilepsy, most patients still receive the standard antiepileptic drugs. This review considers the clinical place and practical use of these agents. Detailed consideration is given to carbamazepine, phenytoin, sodium valproate, phenobarbital and ethosuximide,
Brodie, Martin J., Dichter, Marc A.
openaire +2 more sources
Efficacy and tolerability of adjunctive brivaracetam in patients with prior antiepileptic drug exposure: A post-hoc study. [PDF]
, 2017 Brivaracetam (BRV), a selective, high-affinity ligand for synaptic vesicle protein 2A, is a new antiepileptic drug (AED) for adjunctive treatment of focal (partial-onset) seizures in adults with epilepsy.
Asadi-Pooya, Ali A. +7 more
core +2 more sources
Therapeutic Drug Monitoring and Methods of Quantitation for Carbamazepine [PDF]
, 2017 Carbamazepine is an early anticonvulsant still used today in the treatment of several forms of epilepsy. An active metabolite in the human body contributes to its pharmacological effect.
Ana Vlasceanu +7 more
core +4 more sources
Antiepileptic drug-induced psychosis associated with MTHFR C677T: a case report
Journal of Medical Case Reports, 2019 Background Various antiepileptic drugs can potentially cause psychiatric side effects in patients with epilepsy, but the precise mechanism of these actions remains unknown.
Masaru Shimura +6 more
doaj +1 more source
Teratogenic Effects of Antiepileptic Drugs
Pediatric Neurology Briefs, 1997 Data from 5 prospective European studies totaling 1,221 children exposed to antiepileptic drugs (AED) during pregnancy and 158 children of unexposed control pregnancies were analyzed to quantify the risk of major congenital malformations (MCM) and are ...
J Gordon Millichap
doaj +1 more source
Fish oil (n-3 fatty acids) in drug resistant epilepsy: a randomised placebo-controlled crossover study. [PDF]
, 2014 Backgroundn-3 fatty acids inhibit neuronal excitability and reduce seizures in animal models. High-dose fish oil has been explored in two randomised trials in drug resistant epilepsy with negative results.
DeGiorgio, Christopher M +6 more
core +1 more source
Antiepileptic Drugs and Thyroid Function
Pediatric Neurology Briefs, 2004 Thyroid function in 78 girls and female adolescents (aged 8-18 years) during pubertal development was evaluated while taking carbamazepine (CBZ), oxcarbazepine (OXC), or valproate (VPA) monotherapy for epilepsy and after withdrawal of antiepileptic drugs,
J Gordon Millichap
doaj +1 more source
Current Therapeutic Research, 2020 : Background: Antiepileptic drugs are among the leading causes of drug-induced liver injury (DILI). Due to critical illness, children admitted to intensive care units are more prone to DILI.
Kannan Sridharan, MD, DM +3 more
doaj +1 more source
Lennox-Gastaut Syndrome: A State of the Art Review. [PDF]
, 2017 Lennox-Gastaut syndrome (LGS) is a severe age-dependent epileptic encephalopathy usually with onset between 1 and 8 years of age. Functional neuroimaging studies recently introduced the concept of Lennox-Gastaut as "secondary network epilepsy" resulting ...
Mastrangelo, Mario
core +1 more source
Behavioral Effects of Antiepileptic Drugs
Pediatric Neurology Briefs, 1989 Parental responses to a Child Behavior Checklist were compared before and after changing antiepileptic therapy in an open, parallel design study in the School of Pharmacy and Departments of Neurology and Pediatrics, School of Medicine, University of ...
J Gordon Millichap
doaj +1 more source