Results 21 to 30 of about 37,620 (268)

Behavioral Effects of Antiepileptic Drugs

Pediatric Neurology Briefs, 1989
Parental responses to a Child Behavior Checklist were compared before and after changing antiepileptic therapy in an open, parallel design study in the School of Pharmacy and Departments of Neurology and Pediatrics, School of Medicine, University of ...
J Gordon Millichap
doaj   +1 more source

Effect of Antiepileptic Drugs for Acute and Chronic Seizures in Children with Encephalitis. [PDF]

PLoS ONE, 2015
Encephalitis presents with seizures in the acute phase and increases the risk of late unprovoked seizures and epilepsy. This study aimed to evaluate the effect of antiepileptic drugs in pediatric patients with acute seizures due to encephalitis and ...
Kuang-Lin Lin, Jainn-Jim Lin, Shao-Hsuan Hsia, Min-Liang Chou, Po-Cheng Hung, Huei-Shyong Wang, CHEESE Study Group   +6 more
doaj   +1 more source

Early Withdrawal of Antiepileptic Drugs

Pediatric Neurology Briefs, 1998
Recurrence rate, risk factors for recurrence, and outcome in 161 children after early withdrawal of antiepileptic drugs (AEDs) were studied at Leiden University and other centers in The Netherlands.
J Gordon Millichap
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

New data-driven method to predict the therapeutic indication of redeemed prescriptions in secondary data sources: a case study on antiseizure medications users aged ≥65 identified in Danish registries

BMJ Open
Objectives We aimed to develop a new data-driven method to predict the therapeutic indication of redeemed prescriptions in secondary data sources using antiepileptic drugs among individuals aged ≥65 identified in Danish registries.Design This was an ...
Kristian Kragholm, Carla Carnovale, Emilio Clementi, Maurizio Sessa, Israa Mahmoud, Vera Battini   +5 more
doaj   +1 more source

Challenges in the Treatment of Epilepsy [PDF]

Journal of Kerman University of Medical Sciences, 2012
Epilepsy is one of the most important diseases of nervous system that involves 0.5-1% of the population. In spite of new developments in antiepileptic drugs, between 20-30% of epileptic patients can not be controlled and even those who are controlled ...
H.A Ebrahimi
doaj  

Antiepileptic drugs and bone metabolism

Nutrition & Metabolism, 2006
Anti-epileptic medications encompass a wide range of drugs including anticonvulsants, benzodiazepines, enzyme inducers or inhibitors, with a variety effects, including induction of cytochrome P450 and other enzyme, which may lead to catabolism of vitamin
Labban Barbara, McFarlane Samy I, Arora Surender K, Valsamis Helen A   +3 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Generic Substitutions for Antiepileptic Drugs

Pediatric Neurology Briefs, 1990
The hazards and problems of generic substitutions for antiepileptic drugs are reviewed in a Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology.
J Gordon Millichap
doaj   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source