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Retrospective evaluation of prescribing pattern and utilization of antiepileptic drugs in pediatric, neurosurgery, and psychiatry wards: A comparative study to the standard treatment guidelines. [PDF]
Medicine (Baltimore)Ayaz M +8 more
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Benefits of Combining Antiepileptic Drugs with Vitamin B12 on Redox Balance: Penicillin-Induced Experimental Epilepsy Model. [PDF]
Neuropsychiatr Dis TreatTaskin S, Ozsoy S, Cakir Z.
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Nursing, 2016
Treatment of epilepsy starts with antiepileptic drug (AED) monotherapy. Knowledge of the spectrum of efficacy, clinical pharmacology, and modes of use for individual AEDs is essential for optimal treatment for epilepsy. This article addresses AEDs individually, focusing on key pharmacokinetic characteristics, indications, and modes of use.Older ...
Kavitha S, Dalal, Mary Barna, Bridgeman
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Treatment of epilepsy starts with antiepileptic drug (AED) monotherapy. Knowledge of the spectrum of efficacy, clinical pharmacology, and modes of use for individual AEDs is essential for optimal treatment for epilepsy. This article addresses AEDs individually, focusing on key pharmacokinetic characteristics, indications, and modes of use.Older ...
Kavitha S, Dalal, Mary Barna, Bridgeman
openaire +4 more sources
Current Opinion in Pediatrics, 1996
For many years, the medical treatment of epilepsy was based on the use of the same few drugs, which were chosen according to the seizure type in a fairly standardized manner. In the recent past, there have been several changes, and more are expected in the near future.
M A, Dichter, M J, Brodie
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For many years, the medical treatment of epilepsy was based on the use of the same few drugs, which were chosen according to the seizure type in a fairly standardized manner. In the recent past, there have been several changes, and more are expected in the near future.
M A, Dichter, M J, Brodie
openaire +5 more sources
Physical Medicine and Rehabilitation Clinics of North America, 1999
Antiepileptics are a very important class of medications, and the number of these drugs available for clinical use has increased dramatically in the last decade. The pharmacology and indications for use in a variety of physiatric patient groups are comprehensively and systematically reviewed.
J M, Meythaler, S A, Yablon
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Antiepileptics are a very important class of medications, and the number of these drugs available for clinical use has increased dramatically in the last decade. The pharmacology and indications for use in a variety of physiatric patient groups are comprehensively and systematically reviewed.
J M, Meythaler, S A, Yablon
openaire +2 more sources
Antiepileptic drugs and neurodevelopment
Current Neurology and Neuroscience Reports, 2006Clinical studies have documented the teratogenic potential of antiepileptic drugs (AEDs). More recent cohort studies have been trying to sort out which AEDs impose the highest risk of teratogenicity. Currently, there is evidence demonstrating an increased risk of major congenital malformations (MCMs) for valproate, phenobarbital, and polytherapy during
Gholam K, Motamedi, Kimford J, Meador
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Teratogenicity of antiepileptic drugs
Current Opinion in Neurology, 2019Purpose of review We review data on the comparative teratogenicity of antiepileptic drugs (AEDs), focusing on major congenital malformations (MCMs), intrauterine growth restriction, impaired cognitive development, and behavioral adverse effects following prenatal exposure. Recent findings
Tomson T., Battino D., Perucca E.
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Antiepileptic drugs in development
The Lancet Neurology, 2006Despite the success of several new antiepileptic drugs, about one third of patients with epilepsy are not seizure free on medication. Improvement in this situation might lie in drugs that are currently in development.Some new antiepileptic drugs are modifications of those already available, referred to in this Rapid Review as evolutionary drugs.
John R, Pollard, Jacqueline, French
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Antiepileptic drugs and anesthesia
Pediatric Anesthesia, 2017SummaryAnesthetists commonly encounter epileptic patients when undergoing surgery. This review article discusses the drugs used to treat epilepsy and their relevant effects on anesthesia.
Melanie, Bloor +2 more
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Hypersensitivity to Antiepileptic Drugs
Immunology and Allergy Clinics of North America, 2014Adverse reactions to antiepileptic drugs (AEDs) may lead to treatment failure, morbidity, and mortality. Drug hypersensitivity reactions (DHRs) are potentially fatal. AED DHRs present with a variety of clinical manifestations. The pathogenesis of AED DHRs has not been fully elucidated.
Young-Min, Ye +2 more
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