Concomitant use of combined hormonal contraceptives and antifibrinolytic agents for the management of heavy menstrual bleeding: A practice pattern survey. [PDF]
Thromb Res, 2021 Lim MY +3 more
europepmc +3 more sources
Effectiveness and safety of the use of antifibrinolytic agents in total-knee arthroplasty: A meta-analysis. [PDF]
Medicine (Baltimore), 2020 Ma QM, Han GS, Li BW, Li XJ, Jiang T.
europepmc +2 more sources
Tranexamic Acid; A Glittering Player in the Field of Trauma [PDF]
Bulletin of Emergency and Trauma, 2020 Trauma is still the leading cause of mortality and morbidity worldwide with an estimated 5.8 million mortalities every year [1] and approximately 60 million traumatic brain injuries (TBI) annually [2]. Hemorrhage remains the most common preventable cause
Fariborz Ghaffarpasand +4 more
doaj +1 more source
Bernard-Soulier Syndrome: Identification of a Novel GP1BB Variant in a Mauritanian Patient. [PDF]
Mol Genet Genomic MedThis study identifies a new mutation of the GP1BB gene responsible for Bernard‐Soulier syndrome in a Mauritanian patient. Genetic analysis reveals a nucleotide duplication resulting in a severe platelet adhesion defect. This work highlights the importance of molecular diagnosis and therapeutic strategies to improve the management of affected patients ...
Salem ML, Zein E, Mohamed GS.
europepmc +2 more sources
Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal
Periodontology 2000, EarlyView., 2023 Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra +3 more
wiley +1 more source
Postoperative Low-Dose Tranexamic Acid After Major Spine Surgery: A Matched Cohort Analysis [PDF]
Neurospine, 2020 Objective This was a retrospective, cohort study investigating the efficacy and safety of continuous low-dose postoperative tranexamic acid (PTXA) on drain output and transfusion requirements following adult spinal deformity surgery.
Lauren K. Dunn +13 more
doaj +1 more source
The Effect of Tranexamic Acid (Cyclokapron) on Post–Surgical Bleeding Following the Removal of Impacted Lower Wisdom Teeth in Healthy Individuals [PDF]
Al-Rafidain Dental Journal, 2008 Aims: To evaluate the effect of local irrigation with tranexamic acid in minimizing post–operative bleeding following the removal of impacted lower wisdom teeth.
Rayan S. Hamid +2 more
doaj +1 more source
Tranexamic acid evidence and controversies: An illustrated review
Research and Practice in Thrombosis and Haemostasis, 2021 Tranexamic acid (TXA) is an antifibrinolytic agent commonly used for the treatment or prevention of bleeding. Indications for TXA are diverse, including heavy menstrual bleeding, trauma, postpartum hemorrhage, traumatic brain injury, and surgical site ...
Nicole Relke +2 more
doaj +1 more source
Efficacy and safety of antifibrinolytics in oncological surgery: a systematic review and meta-analysis [PDF]
Revista Brasileira de Anestesiologia, 2019 Background and objectives: The administration of antifibrinolytics has been shown to be effective in reducing blood loss and the need for transfusions in surgeries. However, few studies have evaluated these drugs in cancer surgery.
Aline Menezes Sampaio +7 more
doaj +3 more sources
Synthesis and Hemostatic Activity of New Amide Derivatives
Molecules, 2022 Eight dipeptides containing antifibrinolytic agents (tranexamic acid, aminocaproic acid, 4-(aminomethyl)benzoic acid, and glycine—natural amino acids) were synthesized in a three-step process with good or very good yields.
Lukasz Banach +9 more
doaj +1 more source