Results 11 to 20 of about 5,106 (179)

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Antifibrinolytic agents in current anaesthetic practice [PDF]

British Journal of Anaesthesia, 2013
Antifibrinolytic drugs have become almost ubiquitous in their use during major surgery when bleeding is expected or commonplace. Inhibition of the fibrinolytic pathway after tissue injury has been consistently shown to reduce postoperative or traumatic bleeding. There is also some evidence for a reduction of perioperative blood transfusion.
E, Ortmann, M W, Besser, A A, Klein
openaire   +2 more sources

Efficacy and safety of antifibrinolytics in oncological surgery: a systematic review and meta-analysis [PDF]

Revista Brasileira de Anestesiologia, 2019
Background and objectives: The administration of antifibrinolytics has been shown to be effective in reducing blood loss and the need for transfusions in surgeries. However, few studies have evaluated these drugs in cancer surgery.
Aline Menezes Sampaio, Gabriel Magalhães Nunes Guimarães, Germano Pinheiro Medeiros, Germana Medeiros Mendes Damasceno, Ricardo Martins de Abreu Silva, Rogean Rodrigues Nunes, Hermano Alexandre Lima Rocha, José Carlos Rodrigues Nascimento   +7 more
doaj   +3 more sources

Synthesis and Hemostatic Activity of New Amide Derivatives

Molecules, 2022
Eight dipeptides containing antifibrinolytic agents (tranexamic acid, aminocaproic acid, 4-(aminomethyl)benzoic acid, and glycine—natural amino acids) were synthesized in a three-step process with good or very good yields.
Lukasz Banach, Lukasz Janczewski, Jakub Kajdanek, Katarzyna Milowska, Joanna Kolodziejczyk-Czepas, Grzegorz Galita, Wioletta Rozpedek-Kaminska, Ewa Kucharska, Ireneusz Majsterek, Beata Kolesinska   +9 more
doaj   +1 more source

Safety and Effectiveness of Uterine Gauze Packing for Refractory Postpartum Haemorrhage: A Systematic Review and Meta-Analysis. [PDF]

BJOG
ABSTRACT Background The role of uterine gauze packing in treating refractory postpartum haemorrhage (PPH) is uncertain given limited evidence of benefit and possible harms. Objectives To evaluate the safety and effectiveness of uterine packing using plain gauze or gauze impregnated with haemostatic agent(s) for treating refractory PPH.
Makama M, Ferguson A, Connolly M, Boudova S, Aziz S, Romero L, Vogel JP.   +6 more
europepmc   +2 more sources

Antifibrinolytic role of a bee venom serine protease inhibitor that acts as a plasmin inhibitor. [PDF]

PLoS ONE, 2012
Bee venom is a rich source of pharmacologically active substances. In this study, we identified a bumblebee (Bombus ignitus) venom Kunitz-type serine protease inhibitor (Bi-KTI) that acts as a plasmin inhibitor.
Young Moo Choo, Kwang Sik Lee, Hyung Joo Yoon, Yuling Qiu, Hu Wan, Mi Ri Sohn, Hung Dae Sohn, Byung Rae Jin   +7 more
doaj   +1 more source

Disseminated intravascular and intracardiac thrombosis after cardiopulmonary bypass

Journal of Anaesthesiology Clinical Pharmacology, 2017
Massive intracardiac and intravascular thrombosis is a rare complication following cardiopulmonary bypass (CPB). Most of the cases of the disseminated thrombosis have been reported in patients undergoing complex cardiac surgeries and those receiving ...
Deepak K Tempe, Parin Lalwani, Kapil Chaudhary, Harpreet S Minas, Akhlesh S Tomar   +4 more
doaj   +1 more source

Perioperative hyperfibrinolysis – physiology and pathophysiology

Brazilian Journal of Anesthesiology, 2021
Introduction and objectives: The role of the anesthesiologist in the perioperative management of hemostasis has attracted increasing attention. The fibrinolytic system participates in hemostasis, removing clots after repair of the vascular injury.
David Silveira Marinho
doaj   +1 more source

Anti-fibrinolytic agents in post partum haemorrhage: a systematic review

BMC Pregnancy and Childbirth, 2009
Background Post partum haemorrhage is a leading cause of maternal death worldwide. It also contributes to maternal morbidity as women may require a hysterectomy to control bleeding, or may require a blood transfusion, which can transmit viral infections.
Blackhall Karen, Sydenham Emma, Roberts Ian, Ferrer Pili, Shakur Haleema   +4 more
doaj   +1 more source

COMPARISON OF HEMOSTASIS WITH TRANEXAMIC ACID IN TOTAL KNEE ARTHROPLASTY

Acta Ortopédica Brasileira, 2021
Objective: To compare the use of intravenous and topical tranexamic acid (TXA) in unilateral primary total knee arthroplasty (TKA) in relation to blood loss and complications inherent to the medication.
OTÁVIO MONTOVANELLI MONTEIRO, RODRIGO TURRA PERRONE, FABRÍCIO NASCIMENTO ALMEIDA, CID PEREIRA DE MOURA JUNIOR, SAULO GOMES DE OLIVEIRA, GUSTAVO DALLA BERNARDINA DE ALMEIDA   +5 more
doaj   +1 more source