Results 1 to 10 of about 3,492,596 (401)
Preclinical Pharmacokinetic/Pharmacodynamic Studies and Clinical Trials in the Drug Development Process of EMA-Approved Antifungal Agents: A Review. [PDF]
Clin PharmacokinetPecho T, Zeitlinger M.
europepmc +1 more source
Evaluating cardiac disorders associated with triazole antifungal agents based on the US Food and Drug Administration Adverse Event reporting system database. [PDF]
Front PharmacolChen J, Xu S, Yu W, Sun C, Zhang W.
europepmc +1 more source
Patients with Obesity Should be Recognised as a Special Patient Population During Drug Development of Antibacterial and Antifungal Agents; A Call to Action. [PDF]
Clin Pharmacokinetvan Rhee KP +3 more
europepmc +1 more source
Some of the next articles are maybe not open access.
Medical Journal of Australia, 2007
The four main classes of antifungal drugs are the polyenes, azoles, allylamines and echinocandins. Clinically useful "older" agents include topical azole formulations (for superficial yeast and dermatophyte infections), first-generation triazoles (fluconazole and itraconazole, for a range of superficial and invasive fungal infections), amphotericin B ...
Sharon C A, Chen, Tania C, Sorrell
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The four main classes of antifungal drugs are the polyenes, azoles, allylamines and echinocandins. Clinically useful "older" agents include topical azole formulations (for superficial yeast and dermatophyte infections), first-generation triazoles (fluconazole and itraconazole, for a range of superficial and invasive fungal infections), amphotericin B ...
Sharon C A, Chen, Tania C, Sorrell
openaire +3 more sources
Science, 1961
From the soil of the San Joaquin Valley a fungus has been isolated, an extract of which inhibits the growth of Coccidioides immitis on Sabouraud's medium. An acute toxicity study in mice indicates a certain tolerance of the extract. Tentative identification indicates that the fungus is a penicillium.
M C, EGEBERG, A F, ELCONIN, R O, EGEBERG
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From the soil of the San Joaquin Valley a fungus has been isolated, an extract of which inhibits the growth of Coccidioides immitis on Sabouraud's medium. An acute toxicity study in mice indicates a certain tolerance of the extract. Tentative identification indicates that the fungus is a penicillium.
M C, EGEBERG, A F, ELCONIN, R O, EGEBERG
openaire +2 more sources
Clinical Microbiology Newsletter, 1982
For more than two decades, amphotericin B has been the single broad-spectrum agent for the treatment of systemic mycoses. Amphotericin B is not always effective, must be given parenterally, and is associated with a host of adverse reactions. Despite amphotericin B toxicity, until recently the systemic mycoses did not rate enough attention to prompt a ...
J. R. Gray bill, J. R. Gray bill
openaire +4 more sources
For more than two decades, amphotericin B has been the single broad-spectrum agent for the treatment of systemic mycoses. Amphotericin B is not always effective, must be given parenterally, and is associated with a host of adverse reactions. Despite amphotericin B toxicity, until recently the systemic mycoses did not rate enough attention to prompt a ...
J. R. Gray bill, J. R. Gray bill
openaire +4 more sources
Pharmacokinetics of Antifungal Agents
Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 1993The authors have evaluated the pharmacokinetics of four antifungal agents used in the therapy of fungal peritonitis. Amphotericin B (Amph B) poorly diffuses from blood into peritoneal fluid, which Intraperitoneal administration induces severe abdominal pain.
M V Pellanda +4 more
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Hospital Medicine, 2004
With the relentless increase in invasive fungal infections, particularly in critically ill and immunocompromised patients, it is good to know that there are new additions to the antifungal armamentarium. These include not only new formulations of existing drugs and the development of new triazole agents, but also the introduction of a new class of ...
Anjali Shetty, Rosemary Ann Barnes
openaire +5 more sources
With the relentless increase in invasive fungal infections, particularly in critically ill and immunocompromised patients, it is good to know that there are new additions to the antifungal armamentarium. These include not only new formulations of existing drugs and the development of new triazole agents, but also the introduction of a new class of ...
Anjali Shetty, Rosemary Ann Barnes
openaire +5 more sources
Seminars in Respiratory Infections, 2002
Treatment of fungal infections is an area of increasing concern. This is because of the complexity of underlying illness in affected patients as well as the limited number of antifungal agents available for use. Current strategies focus on prevention of these infections in patients at high risk; however, this has the potential to lead to the emergence ...
John R. Perfect +2 more
openaire +6 more sources
Treatment of fungal infections is an area of increasing concern. This is because of the complexity of underlying illness in affected patients as well as the limited number of antifungal agents available for use. Current strategies focus on prevention of these infections in patients at high risk; however, this has the potential to lead to the emergence ...
John R. Perfect +2 more
openaire +6 more sources