Results 241 to 250 of about 2,517,016 (285)
Characterisation of Antifungal Resistance to Azoles in Colombian Isolates of Malassezia spp. [PDF]
MycosesGalvis-Marín JC +4 more
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Candida auris can acquire antifungal resistance without selection pressure
Phan-Canh T +6 more
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Fitness cost of antifungal resistance
Nature Reviews Microbiology, 2022Grant Otto
exaly +3 more sources
Resistance to Antifungal Drugs
Infectious Disease Clinics of North America, 2021Pathogenic fungi have several mechanisms of resistance to antifungal drugs, driven by the genetic plasticity and versatility of their homeostatic responses to stressful environmental cues. We critically review the molecular mechanisms of resistance and cellular adaptations of pathogenic fungi in response to antifungals and discuss the factors ...
Ronen, Ben-Ami +1 more
openaire +2 more sources
Antifungal resistance in mucorales
International Journal of Antimicrobial Agents, 2017The order Mucorales, which includes the agents of mucormycosis, comprises a large number of species. These fungi are characterised by high-level resistance to most currently available antifungal drugs. Standardised antifungal susceptibility testing methods are now available, allowing a better understanding of the in vitro activity of antifungal drugs ...
Eric Dannaoui
exaly +3 more sources
Clinical Infectious Diseases, 2003
The increasing incidence of invasive fungal infections is the result of many factors, including an increasing number of patients with severe immunosuppression. Although new drugs have been introduced to combat this problem, the development of resistance to antifungal drugs has become increasingly apparent, especially in patients who require long-term ...
Juergen, Loeffler, David A, Stevens
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The increasing incidence of invasive fungal infections is the result of many factors, including an increasing number of patients with severe immunosuppression. Although new drugs have been introduced to combat this problem, the development of resistance to antifungal drugs has become increasingly apparent, especially in patients who require long-term ...
Juergen, Loeffler, David A, Stevens
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Defining the frontiers between antifungal resistance, tolerance and the concept of persistence
Drug Resistance Updates, 2015 A restricted number of antifungal agents are available for the therapy of fungal diseases. With the introduction of epidemiological cut-off values for each agent in important fungal pathogens based on the distribution of minimal inhibitory concentration (
Dominique Sanglard, Eric Delarze
exaly +2 more sources
Resistance to Antifungal Agents
Pediatric Clinics of North America, 1995The marked increase in the number of patients with AIDS and other forms of immunocompromise has resulted in the emergence of fungi as predominant pathogens in many institutions. Unfortunately, with the widespread use of antifungal agents to combat these infections, reports of resistance to antifungal agents have proliferated. In the present environment,
G P, DeMuri, M K, Hostetter
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Update on antifungal resistance
Trends in Microbiology, 1997Overuse of antifungal agents has resulted in the selection of naturally resistant Candida species, as well as expression of resistance from previously susceptible species resulting from genetic mutations and/or selection of resistant subpopulations.
M E, Klepser, E J, Ernst, M A, Pfaller
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Antifungal Drug Resistance in Aspergillus
Journal of Infection, 2000This article overviews the emerging problem of antifungaldrug resistance in Aspergillus. Fluconazole and ketocona-zole (KCZ) are inactive against Aspergillus. Validation oftesting procedures for the detection of itraconazole (ITZ)resistance in Aspergillus fumigatusin 19971,2were furthervalidated with posaconazole (SCH-56592)3,4and voricona-zole (VCZ)5 ...
Moore, C.B. +4 more
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