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CLINICAL RELEVANCE OF ANTIFUNGAL RESISTANCE
Infectious Disease Clinics of North America, 1997The availability of standard guidelines (NCCLS M27 document) for antifungal susceptibility testing has facilitated the establishment of tentative interpretive breakpoints for fluconazole and itraconazole by the NCCLS. Based on correlations of MIC values with the outcomes of patients with mostly Candida infections, fluconazole MICs of > or = 64 and ...
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Fungal infections pose an important threat to public health and food security, and with the rise in antifungal drug and fungicide resistance, we are faced with a global crisis. Currently, humanity is at an intersection of global climate change driving the expansion of species range distributions, emergence of novel pathogenic fungi, and changing at ...
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Tackling the emerging threat of antifungal resistance to human health
Nature Reviews Microbiology, 2022Adilia Warris +2 more
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Resistance to Antifungal Drugs
2003Abstract Fungal infections caused by fungal pathogens remain quite common in immunocompromised hosts, especially in HIV-infected individuals, and in patients given immunosuppressive drugs or broad-spectrum antibiotics. Candida spp. represent the major group of yeast species recovered from these infected individuals; however, other yeasts
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Antifungal Resistance: An Emerging Battlefield
Future Microbiology, 2020Patrick Cy, Woo +2 more
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Mechanisms of antifungal resistance.
Revista iberoamericana de micologia, 2007The many drugs that are available at present to treat fungal infections can be divided into four broad groups on the basis of their mechanism of action. These antifungal agents either inhibit macromolecule synthesis (flucytosine), impair membrane barrier function (polyenes), inhibit ergosterol synthesis (allylamines, thiocarbamates, azole derivatives ...
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Antibiotic resistance in the patient with cancer: Escalating challenges and paths forward
Ca-A Cancer Journal for Clinicians, 2021Amila K Nanayakkara, David E Greenberg
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