Results 81 to 90 of about 116,695 (299)

A Cross-sectional Study Comparing the in vitro Biofilm Optical Density of Dermatophytic Isolates with Clinical Profile, Risk Factors, and Antifungal Susceptibility

open access: yesIndian Journal of Dermatology
Background: In India, Trichophyton mentagrophytes has emerged as the dominant cause of dermatophytosis, surpassing Trichophyton rubrum, contributing to an epidemic-like surge in cases. The Indian genotype “T.
Deepika Pandhi   +4 more
doaj   +1 more source

An update on antifungal resistance in dermatophytosis

open access: yesExpert Opinion on Pharmacotherapy
The reports of resistance to antifungal agents used for treating onychomycosis and other superficial fungal infections are increasing. This rise in antifungal resistance poses a public health challenge that requires attention. This review explores the prevalence of dermatophytes and the current relationship between dermatophyte species, their minimum ...
Aditya K. Gupta   +3 more
openaire   +2 more sources

Autophagy Alters the Susceptibility of Candida albicans Biofilms to Antifungal Agents [PDF]

open access: yes, 2023
Candida albicans (C. albicans) reigns as a major cause of clinical candidiasis. C. albicans biofilms are known to increase resistance to antifungal agents, making biofilm-related infections particularly challenging to treat.
Jiadi Shen   +6 more
core   +1 more source

Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review

open access: yesAdvanced Materials, EarlyView.
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase   +6 more
wiley   +1 more source

No Increase in Frequency of Antifungal Resistance among Yeasts Isolated from Normally Sterile Sites in Patients at Foothills Hospital from 1993 to 1996

open access: yesCanadian Journal of Infectious Diseases, 1999
OBJECTIVE: To determine the prevalence of resistance to antifungal drugs among yeasts isolated from sterile sites from patients in one hospital and the relationship of resistance to antifungal use, and to assess whether resistance was increasing.
A Patrick Gibb   +2 more
doaj   +1 more source

Antifungal Resistance Regarding Malassezia pachydermatis: Where Are We Now?

open access: yesJournal of Fungi, 2020
Malassezia pachydermatis is a yeast inhabiting the skin and ear canals in healthy dogs. In the presence of various predisposing conditions it can cause otitis and dermatitis, which are treated with multiple antifungal agents, mainly azole derivatives ...
Andrea Peano   +5 more
doaj   +1 more source

MOLECULAR MECHANISMS OF DRUG RESISTANCE IN CANDIDA ALBICANS: ROLE OF TRANSCRIPTION FACTORS MCM1 AND ADA2 [PDF]

open access: yes, 2011
Candida albicans is an opportunistic fungal pathogen responsible for localized as well as disseminated infections. C. albicans is the most commonly isolated specie from blood cultures, accounting for over 60% of all Candida isolates. The fungistatic drug
MOGAVERO, SELENE
core  

Hard‐Magnetic Soft Millirobots in Underactuated Systems

open access: yesAdvanced Robotics Research, EarlyView.
This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang   +4 more
wiley   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui   +14 more
wiley   +1 more source

Exploring the Molecular Basis of Antifungal Synergies Using Genome-Wide Approaches

open access: yesFrontiers in Microbiology, 2012
Drug resistance poses a significant challenge in antifungal therapy since resistance has been found for all known classes of antifungal drugs. The discovery of compounds that can act synergistically with antifungal drugs is an important strategy to ...
Ameeta eAgarwal   +6 more
doaj   +1 more source

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