Results 71 to 80 of about 190,632 (309)

No Increase in Frequency of Antifungal Resistance among Yeasts Isolated from Normally Sterile Sites in Patients at Foothills Hospital from 1993 to 1996

Canadian Journal of Infectious Diseases, 1999
OBJECTIVE: To determine the prevalence of resistance to antifungal drugs among yeasts isolated from sterile sites from patients in one hospital and the relationship of resistance to antifungal use, and to assess whether resistance was increasing.
A Patrick Gibb, Cheryl Thorson, Harry van den Elzen   +2 more
doaj   +1 more source

Brine Shrimp Toxicity Evaluation of Some Tanzanian Plants Used Traditionally for the Treatment of Fungal Infections. [PDF]

, 2006
Plants which are used by traditional healers in Tanzania have been evaluated to obtain preliminary data of their toxicity using the brine shrimps test. The results indicate that 9 out of 44 plant species whose extracts were tested exhibited high toxicity
Hamza, Omar J M, Kapingu, Modest C, Masimba, Pax J, Matee, Mecky I N, Mbwambo, Zakaria H, Mikx, Frans, Moshi, Mainen J, Nondo, Ramadhani O S, van den Beukel, Carolien J P, van der Ven, André J A M, Verweij, Paul E   +10 more
core   +1 more source

Caspofungin Treatment of Aspergillus fumigatus Results in ChsG-Dependent Upregulation of Chitin Synthesis and the Formation of Chitin-Rich Microcolonies [PDF]

, 2015
Date of Acceptance: 23/07/2015 We thank Gillian Milne for help with electron microscopy, Sophie M. Schäfer for pilot experiments, and Emilia Mellado for strains. All authors acknowledge financial support of Gilead Sciences through Ph.D.
Gow, Neil A R, Lee, Keunsook, Munro, Carol A, Walker, Louise A   +3 more
core   +1 more source

Stable Protein‐Based G‐Quadruplex‐Derived Supramolecular Bioinks as Tunable ECM‐Mimetic Constructs Assembled by Combining Non‐Covalent and Covalent Strategies

Advanced Materials, EarlyView.
Harnessing the synergistic interplay of supramolecular self‐assembly, under macromolecular crowding conditions, and enzymatic‐mediated covalent crosslinking toward a stable protein‐based G‐quadruplex‐derived supramolecular bioink. This bioinspired strategy enables the biofabrication of complex and tunable ECM‐mimetic constructs, providing a platform ...
Vera Sousa, Rita Sobreiro‐Almeida, Bart W. L. van den Bersselaar, E. W. Meijer, Ghislaine Vantomme, João Borges, João F. Mano   +6 more
wiley   +1 more source

Exploring the Molecular Basis of Antifungal Synergies Using Genome-Wide Approaches

Frontiers in Microbiology, 2012
Drug resistance poses a significant challenge in antifungal therapy since resistance has been found for all known classes of antifungal drugs. The discovery of compounds that can act synergistically with antifungal drugs is an important strategy to ...
Ameeta eAgarwal, Siddharth eTripathi, Tao eXu, Melissa eJacob, Xing-Cong eLi, Alice eClark, Alice eClark   +6 more
doaj   +1 more source

Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives [PDF]

, 2010
A simple and efficient method has been developed for the synthesis of various 2-quinoxalinone-3-hydrazone derivatives using microwave irradiation technique. The series of 2-quinoxalinone-3-hydrazone derivatives synthesized, were structurally confirmed by
Ajani, Olayinka O.
core   +1 more source

Multifunctional Bio‐Based Packaging for Perishable Foods: Structural Design, Scalable Fabrication, and Versatile Applications

Advanced Materials, EarlyView.
An overview of design principles and scalable fabrication strategies for multifunctional bio‐based packaging. Radiative cooling films, modified‐atmosphere films/membranes, active antimicrobial/antioxidant platforms, intelligent optical/electrochemical labels, and superhydrophobic surfaces are co‐engineered from material chemistry to mesoscale structure
Lei Zhang, Jiaqi Zhang, Mei Cui, Wei Qi, Renliang Huang, Rongxin Su, Kai Zhang   +6 more
wiley   +1 more source

Global Antifungal Profile Optimization of Chlorophenyl Derivatives against Botrytis cinerea and Colletotrichum gloeosporioides [PDF]

, 2009
Twenty-two aromatic derivatives bearing a chlorine atom and a different chain in the para or meta position were prepared and evaluated for their in vitro antifungal activity against the phytopathogenic fungi Botrytis cinerea and Colletotrichum ...
Aleu J., Aleu J., Aleu J., Barbosa D., Barbosa de Oliveira D., Burkert U., Bustillo A. J., Bustillo A. J., Bustillo A. J., Clark T., Coleman T. F., Coleman T. F., Coley-Smith J. R., Colmenares A. J., Cruciani G., Cruz-Monteagudo M., Cruz-Monteagudo M., De Boor C., Duke S. O., Echeverri F., Efron B., Eriksson L., Gerald C. F., Gramatica P., Hasegawa K., Hou T. J., Leardi R., Patil I. S., Reino J. L., Saiz-Urra L., Van Waterbeemd H., Yasri A.   +31 more
core   +2 more sources

Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming

Advanced Materials, EarlyView.
Matrix viscoelasticity is a key mechanical feature of the tumor microenvironment but remains poorly understood in immune regulation. Here, we develop a tunable collagen platform to decouple viscoelasticity from stiffness and show that slow‐relaxing matrices constrain dendritic cell migration by limiting actomyosin‐driven matrix remodeling, thereby ...
Wei‐Hung Jung, Emie Humann, Joshua M. Price, Yoav Binenbaum, Azra Haseki, Sanjana Iyer, David J. Mooney   +6 more
wiley   +1 more source

Calli Essential Oils Synergize with Lawsone against Multidrug Resistant Pathogens. [PDF]

, 2017
The fast development of multi-drug resistant (MDR) organisms increasingly threatens global health and well-being. Plant natural products have been known for centuries as alternative medicines that can possess pharmacological characteristics, including ...
Alsaadi, Abrar I, Husseiny, Mohamed I, Ibrahim, Ashraf S, Khitrov, Gregory, Noreddin, Ayman M, Soliman, Sameh SM, Youssef, Eman G   +6 more
core   +2 more sources