Results 101 to 110 of about 66,504 (305)

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk, Ryan Jin, Fabio Tuzzolino, Giusy Ranucci, Donatella Madonia, Alessio Provenzani   +5 more
wiley   +1 more source

In Vitro Antifungal Activity of Essential Oils and Nanoemulsions of Zingiber cassumunar and Cymbopogon citratus Against Planktonic and Biofilm Forms of Malassezia pachydermatis

Antibiotics
Malassezia pachydermatis is a yeast pathogen associated with recurrent skin and ear infections in dogs, often complicated by biofilm formation and reduced antifungal susceptibility.
Sirikorn Promcham, Orawan Limsivilai, Theerawat Kritsadasima, Suttiwee Chermprapai, Natthasit Tansakul, Pareeya Udomkusonsri, Chompoonek Yurayart   +6 more
doaj   +1 more source

Relationship between continuous infusion meropenem PK/PD target attainment and C‐reactive protein dynamics in onco‐haematologic patients with febrile neutropenia

British Journal of Clinical Pharmacology, EarlyView.
Aim Meropenem is a second‐line antimicrobial agent in the treatment of febrile neutropenia in onco‐haematological patients. A population pharmacokinetic/pharmacodynamic (PK/PD) analysis for assessing the relationship between meropenem exposure and C‐reactive protein (C‐RP) over time was conducted.
Chun Liu, Pier Giorgio Cojutti, J. G. Coen van Hasselt, Michele Bartoletti, Maddalena Giannella, Pierluigi Zinzani, Pierluigi Viale, Federico Pea   +7 more
wiley   +1 more source

Personalized antifungal susceptibility testing [PDF]

Journal of Antimicrobial Chemotherapy, 1999
CONTI, Stefania, FANTI F., BERTOLOTTI D., DIECI E., ARSENI S., SALATI A., POLONELLI, Luciano   +6 more
openaire   +5 more sources

Enhancing the Secretion Systems: Genetic Engineering of Super Bioagents for Effective Plant Disease Control

Biotechnology and Bioengineering, EarlyView.
Genetic engineering (GE) overcomes BCA limits, enabling robust, scalable crop protection. “Super Bioagents” (SBs) use optimized SSs to enhance bioactive molecule delivery. Optimizing SSs enhance precise, sustainable effector deployment for stable disease suppression. SBs use microbiome‐informed design for scalable, next‐gen sustainable crop protection.
Michael Dare Asemoloye
wiley   +1 more source

Efficacy of an abbreviated induction regimen of amphotericin B deoxycholate for cryptococcal meningoencephalitis: 3 days of therapy is equivalent to 14 days. [PDF]

, 2014
Cryptococcal meningoencephalitis is an urgent global health problem. Induction regimens using 14 days of amphotericin B deoxycholate (dAmB) are considered the standard of care but may not be suitable for resource-poor settings.
Sharp, Andrew D, Andrew D. Sharp, Julie A. Schwartz, Gregson, Lea, Howard, Susan J, Goodwin, Joanne, Susan J. Howard, Bill Moser, John R. Perfect, Müller, W, Sharp, AD, Joanne Goodwin, Moser, Bill, Walker, Catherine, Hope, William W, Lea Gregson, Hope, WW, Perfect, John R, Joanne Livermore, Werner Müller, Schwartz, JA, William W. Hope, Felton, Timothy; id_orcid, Timothy Felton, Catherine Walker, Livermore, J, Schwartz, Julie A, Gregson, L, Goodwin, J, Harrison, Thomas S, Livermore, Joanne, Howard, SJ, Felton, T, Harrison, TS, Walker, C, Perfect, JR, Thomas S. Harrison, Müller, Werner; id_orcid, Moser, B   +38 more
core   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Antifungal susceptibility testing in Aspergillus spp. according to EUCAST methodology [PDF]

, 2006
The availability of new antifungal agents has multiplied the demand for in vitro antifungal susceptibility testing for Aspergillus spp. The European Committee on Antimicrobial Susceptibility Testing (EUCAST) has charged its Antifungal Susceptibility ...
Lass-Flörl, C., Rodriguez-Tudela, J. L., Denning, D. W.; id_orcid, Cuenca-Estrella, M.   +3 more
core   +1 more source

Antifungal drug susceptibility of Candida albicans

East African Medical Journal, 2002
To determine the susceptibility of clinical isolates of Candida albicans and to establish the minimum inhibitory concentrations (MIC) to commonly used antifungal drugs.Laboratory based experiment.Mbagathi District Hospital, Nairobi, Kenya.Candida albicans isolated between 1998 and 2000 from the sputa of HIV/AIDS patients and throat swabs of children ...
Bii, C. C., Ouko, T. T., Amukoye, E., Githinji, L. W.   +3 more
openaire   +4 more sources

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source