Results 111 to 120 of about 66,504 (305)

Invitro Susceptibility Test of Candida spp. Isolates From Pulmonary Tuberculosis Suspected Patients to Antifungal Agents in Jakarta [PDF]

, 2012
Pulmonary infection is still a major health concern in Indonesia, and fungal infection is emerging. This may be related to widely used broad spectrum antibiotics, steroids, oral contraceptive, cytostatic, and chronic diseases.The aim of this study was to
Kumala, Widyasari, H. W, Mardiastuti
core  

Hsp90 governs dispersion and drug resistance of fungal biofilms [PDF]

, 2011
Fungal biofilms are a major cause of human mortality and are recalcitrant to most treatments due to intrinsic drug resistance. These complex communities of multiple cell types form on indwelling medical devices and their eradication often requires ...
Ramage Gordon, Lopez-Ribot, J.L., Rajendran Ranjith, Ramage, G., Leah E. Cowen, Uppuluri Priya, Robbins, N., Priya Uppuluri, Rajendran, R., Andes, D., Jose L Lopez-Ribot, David Andes, Leah E Cowen, Nicole Robbins, Uppuluri, P., Robbins Nicole, Nett Jeniel, Lopez-Ribot Jose L., Jose L. Lopez-Ribot, Cowen, L.E., Nett, J., Ranjith Rajendran, Gordon Ramage, Jeniel Nett, Andes David, Cowen Leah E.   +25 more
core   +1 more source

Neosartorya udagawae pulmonary infection requiring a surgical treatment in a paediatric haematopoietic progenitor cell recipient

Medical Mycology Case Reports
Neosartorya udagawae is a known cause of fungal infection in humans and animals. It is found to be more refractory to antifungal treatment in comparison to other Aspergillus species.
Olga S. Tatarinova, Caroline L. Furness, Andrew M. Borman, Joy Barber, Nagarajan Muthialu, Laura Ferreras-Antolin   +5 more
doaj   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Distribution and Antifungal Susceptibility of Candida Species Isolated from Blood Cultures

Cerrahpaşa Medical Journal
Objective: Candidemia is defined as the isolation of Candida species from blood and is an infection with high mortality and morbidity. Although Candida albicans is the most common causative agent of candidemia in blood cultures, the detection rate of ...
Fadime Yılmaz Yücel, Hülya Duran
doaj   +1 more source

Ruxolitinib Pharmacokinetics and Exposure–Toxicity Relationship in Hematologic Malignancies and Immune‐Mediated Diseases: A Prospective Observational Study

Clinical Pharmacology &Therapeutics, EarlyView.
Ruxolitinib pharmacokinetics (PK) has been characterized in clinical trials but remains poorly documented in real‐world practice. This project aimed to investigate ruxolitinib PK in routine clinical practice, identify factors driving its variability, and explore exposure–response relationships to assess the potential role of therapeutic drug monitoring.
Jérémie Tachet, Sara C. Meyer, Francesco Grandoni, Emmanuel Haefliger, Monika Nagy‐Hulliger, Jörg P. Halter, Jakob R. Passweg, David Haefliger, Carine Bardinet, Laurent A. Decosterd, Monia Guidi, François R. Girardin   +11 more
wiley   +1 more source

Clinical significance and antifungal susceptibility profile of 103 clinical isolates of Scedosporium species complex and Lomentospora prolificans obtained from NIH patients

Journal of Clinical Microbiology
Reduced susceptibility to antifungals is common among members of genera Scedosporium and Lomentospora, with optimal treatments still not fully defined.
Mary M. Czech, Jennifer Cuellar-Rodriguez, Kyung J. Kwon-Chung, Frida Stock, Chioma I. Aneke, Kenneth N. Olivier, Kevin P. Fennelly, Juan Gea-Banacloche, Christa S. Zerbe, Alexandra F. Freeman, Steven M. Holland, Michail S. Lionakis, Amir Seyedmousavi   +12 more
doaj   +1 more source

Fecal Microbiota Transplantation and Microbiota‐Based Therapeutics in Allogeneic Hematopoietic Stem Cell Transplantation: Current Evidence and Future Directions

Clinical Pharmacology &Therapeutics, EarlyView.
The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó, Dorina Korózs, Michal Bator, Krisztina Jeszenszky, Viktor Lakatos, László Gopcsa, Péter Reményi, János Sinkó   +7 more
wiley   +1 more source

Oral Yeast Colonization and Fungal Infections in Peritoneal Dialysis Patients: A Pilot Study

Canadian Journal of Infectious Diseases and Medical Microbiology, 2017
Peritonitis and exit-site infections are important complications in peritoneal dialysis (PD) patients that are occasionally caused by opportunistic fungi inhabiting distant body sites.
Liliana Simões-Silva, Sara Silva, Carla Santos-Araujo, Joana Sousa, Manuel Pestana, Ricardo Araujo, Isabel Soares-Silva, Benedita Sampaio-Maia   +7 more
doaj   +1 more source

Fusarium solani keratitis: role of antifungal susceptibility testing and identification to the species level for proper management

Brazilian Journal of Infectious Diseases, 2019
We report a patient with fungal keratitis caused by a multiresistant Fusarium solani in a tertiary care hospital located in southern Brazil. A 55-year-old man with a history of ocular trauma presented with keratitis in left eye.
Priscila Dallé Rosa, Karla Sheid, Claudete Locatelli, Diane Marinho, Luciano Goldani   +4 more
doaj   +1 more source