Results 191 to 200 of about 32,347 (265)

Nootkatone antifungal activity and calcium signaling-mediated resistance in Aspergillus fumigatus. [PDF]

Appl Microbiol Biotechnol
Xu J, Song L, Chen Y, Tang J, Lv X, Du H, Song J, Tian J.   +7 more
europepmc   +1 more source

Association of Helicobacter pylori with Candida albicans enhances fungal virulence and stress tolerance. [PDF]

Gut Pathog
Sun J, Luo Q, Yang T, Xu X, Luo T, Jian H, Chen X, Cui G, Chen Z.   +8 more
europepmc   +1 more source

Efficacy and Safety of Dupilumab in Chinese Adult Patients With Chronic Rhinosinusitis With Nasal Polyps: A Randomized, Placebo‐Controlled, Phase III Trial

Allergy, EarlyView.
Dupilumab significantly improved nasal polyp score, nasal congestion, olfaction, total symptom score, and disease‐specific quality of life in Chinese patients with uncontrolled CRSwNP. Incidence of treatment‐emergent adverse events was similar between dupilumab and placebo.
Mu Xian, Menglin Wang, Changqing Zhao, Lijia Wan, Yu Xu, Juan Meng, Rui Xu, Xicheng Song, Li Shi, Yucheng Yang, Yan Jiang, Yanzhen Wu, Bethany Ling, Vivian Li, Andrew P. Fontenot, Lacey R. Robinson, Neelam A. Phadke, Chengshuo Wang, Luo Zhang   +18 more
wiley   +1 more source

Introducing silica-solubilizing and plant growth-promoting bacteria from sugarcane as inducers of drought stress tolerance. [PDF]

Sci Rep
Kamyab M, Motamedi H.
europepmc   +1 more source

Agonist‐specific conformational dynamics at the β2‐adrenoceptor dictate allosteric modulation of Gαs signalling and bronchodilation

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah, Joshua Richard, Suvankar Ghosh, Jillian Jerwick, Joice T. Gavali, Raymond B. Penn, Alexander D. MacKerell Jr, Deepak A. Deshpande   +7 more
wiley   +1 more source

Ovoid cell is an inducible small-sized morphotype that enhances proliferation and antifungal drug tolerance in the human fungal pathogen Cryptococcus neoformans. [PDF]

PLoS Pathog
Zhang X, Shu X, Liu Y, Zhao Y, Chen H, Xiong F, Kang M, Cao C.   +7 more
europepmc   +1 more source

Dental Pulp Stem Cell‐Derived Intracellular Vesicles Inhibit OSCC by Delivering PTEN to Suppress PI3K/AKT/mTOR Signalling Pathway

Cell Proliferation, EarlyView.
DPSC‐IVs suppressed PI3K/AKT/mTOR signalling pathway by delivering PTEN to tumour cells, which reduced the expression of Bcl‐2 and elevated that of Bax. Meanwhile, DPSC‐IVs activated PINK1/Parkin mediated mitophagy, which further raised ROS levels.
Yu Luo, Qiang Qin, Wenting She, Xiangying Wang, Xiqin Li, Chenxuan Shu, Ruohan Li, Ziwei Li, Dongjie Fu, Yan He, Qingsong Ye   +10 more
wiley   +1 more source

Biocide Response of Candida auris. [PDF]

Mycoses
Erganis S, Ozturk A, Sahin EA, Kalkanci A.   +3 more
europepmc   +1 more source

Characterization of bacterial endophytes isolated from <i>Cannabis sativa</i> L. and <i>Chelidonium majus</i> L. for their application as biostimulants and biocontrol agents. [PDF]

Front Microbiomes
Kaddoura MJ, Amaya-Quiroz L, Rani M, Shah Z, Reghunadh K, Samsatly J, Meglouli H, George S.   +7 more
europepmc   +1 more source

Empagliflozin Versus Dapagliflozin and Urogenital Adverse Events in Type 2 Diabetes: A Target Trial Emulation

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Urogenital adverse events are common with sodium‐glucose co‐transporter 2 inhibitors (SGLT2i) and may influence treatment decisions. Variations in SGLT2i selectivity, potency and effects on renal glucose excretion could lead to differences in safety profiles. We compared the risks of urinary tract infection (UTI), genital tract infection (
Christine Ljungberg, Kasper Bonnesen, Morten Schmidt, Christina Vandenbroucke‐Grauls, Michael Dalager‐Pedersen, Henrik Toft Sørensen, Mette Nørgaard, Reimar Wernich Thomsen   +7 more
wiley   +1 more source