Results 31 to 40 of about 1,150,155 (343)

Aggresome formation by anti-Ras intracellular scFv fragments. The fate of the antigen-antibody complex.

open access: yesEuropean Journal of Biochemistry, 2001
Diverting the antigen from its normal intracellular location to other compartments in an antibody-mediated way represents a mode of action for intracellular antibodies [Cardinale, A., Lener, M., Messina, S., Cattaneo, A. & Biocca, S.
A. Cardinale, I. Filesi, S. Biocca
semanticscholar   +1 more source

Evaluation of a new system (RAD 120) for the serologic determination of the T.O.R.C.H complex analytes

open access: yesMicrobiologia Medica, 2010
The aim of this study was to evaluate the results of the determination of IgG and IgM against TORCH complex antigens obtained by using a new automatic random-access (RAD 120 – RADIM/SEAC) instrument based on FEIA method, in comparison with the results ...
Mauro Carcheri   +9 more
doaj   +1 more source

Antibodies for immunolabeling by light and electron microscopy : not for the faint hearted [PDF]

open access: yes, 2014
Reliable antibodies represent crucial tools in the arsenal of the cell biologist and using them to localize antigens for immunocytochemistry is one of their most important applications.
Griffiths, Gareth, Lucocq, John Milton
core   +1 more source

Vaccine-induced immune thrombotic thrombocytopenia: Updates in pathobiology and diagnosis

open access: yesFrontiers in Cardiovascular Medicine, 2022
Coronavirus disease 2019 (COVID-19) is a viral respiratory infection caused by the severe acute respiratory syndrome virus (SARS-CoV-2). Vaccines that protect against SARS-CoV-2 infection have been widely employed to reduce the incidence of symptomatic ...
Stefan D. Jevtic   +10 more
doaj   +1 more source

Antigen, antibody and immune complex detection in serum samples from rats experimentally infected with Strongyloides venezuelensis [PDF]

open access: yes, 2012
In order to establish an antigen, antibody and immune complex detection by enzyme-linked immunosorbent assay (ELISA) in serum samples, normal or immunocompromised Wistar rats experimentally infected with Strongyloides venezuelensis were used.
Costa-Cruz, Julia M.   +3 more
core   +1 more source

Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy

open access: yesJournal for ImmunoTherapy of Cancer, 2022
Background The current therapeutic antibodies and chimeric antigen receptor (CAR) T cells are capable of recognizing surface antigens, but not of intracellular proteins, thus limiting the target coverage for drug development.
Xin Liu   +14 more
doaj   +1 more source

A novel interdigitated capacitor based biosensor for detection of cardiovascular risk marker [PDF]

open access: yes, 2009
C-reactive protein (CRP) is a potential biomarker whose elevated levels in humans determine cardiovascular disease risk and inflammation. In this study, we have developed a novel capacitive biosensor for detection of CRP-antigen using capacitor with ...
Davidson, Jimmy L.   +3 more
core   +1 more source

High affinity antigen recognition of the dual specific variants of herceptin is entropy-driven in spite of structural plasticity. [PDF]

open access: yesPLoS ONE, 2011
The antigen-binding site of Herceptin, an anti-human Epidermal Growth Factor Receptor 2 (HER2) antibody, was engineered to add a second specificity toward Vascular Endothelial Growth Factor (VEGF) to create a high affinity two-in-one antibody bH1 ...
Jenny Bostrom   +4 more
doaj   +1 more source

Cell-type specific potent Wnt signaling blockade by bispecific antibody. [PDF]

open access: yes, 2018
Cell signaling pathways are often shared between normal and diseased cells. How to achieve cell type-specific, potent inhibition of signaling pathways is a major challenge with implications for therapeutic development.
Bidlingmaier, Scott   +6 more
core   +2 more sources

The requirement for the Fc portion of antibody in antigen-antibody complex-mediated suppression.

open access: yesJournal of Immunology, 1978
The role of the Fc portion of antibody in immune complex-induced suppression was studied in vivo and in vitro. BSA pheasant anti-BSA complexes, formed in antigen excess (Ag1Ab1), were found to suppress both responses to BSA and SRBC.
E. Morgan, C. Tempelis
semanticscholar   +1 more source

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