Results 91 to 100 of about 2,473,811 (360)
Expression of cluster of differentiation 1a-positive langerhans cells in oral lichen planus
Indian Journal of Dermatology, 2019 Background/Purpose: Lichen planus is a T-cell-mediated mucocutaneous disorder characterized histopathologically by a band of chronic inflammatory cells in the subepithelial zone and degeneration of basal layer. The present study was aimed to evaluate the
Thankanadar Arul Kumar +5 more
doaj +1 more source
Modelling cell-cell collision and adhesion with the Filament Based Lamellipodium Model [PDF]
arXiv, 2018 We extend the live-cell motility Filament Based Lamellipodium Model to incorporate the forces exerted on the lamellipodium of the cells due to cell-cell collision and cadherin induced cell-cell adhesion. We take into account the nature of these forces via physical and biological constraints and modelling assumptions. We investigate the effect these new
arxiv
Antigen Presentation by MHC-Dressed Cells [PDF]
Frontiers in Immunology, 2015 Professional antigen-presenting cells (APCs) such as conventional dendritic cells (DCs) process protein antigens to MHC-bound peptides and then present the peptide-MHC complexes to T cells. In addition to this canonical antigen presentation pathway, recent studies have revealed that DCs and non-APCs can acquire MHC class I (MHCI) and/or MHC class II ...
openaire +4 more sources
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Frontiers in Pharmacology, 2018 Dendritic cells (DCs) are important to the immune system and are frequently recruited to hypoxic regions, especially during acute myocardial infarction (AMI).
Hongyun Jiang +5 more
doaj +1 more source
IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells.
Journal of Immunology, 1991 Murine IL-10 (cytokine synthesis inhibitory factor) inhibits cytokine production by Th1 cell clones when they are activated under conditions requiring the presence of APC. By preincubating APC with IL-10, we demonstrate that IL-10 acts principally on APC
D. Fiorentino +6 more
semanticscholar +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
The cell cycle related rhythms, cells' states correlation and the cancer [PDF]
arXiv, 2015 We consider the decision making by mammalian cells, looking them as dynamic systems with rhythms. We calculate the effective dimension of the cell division model of the healthy mammalian cells consistent with the data: it is described via a four dimensional dynamic system. We assume that the cell's decision making property is strongly affected by the
arxiv
Nanoparticle-Based Manipulation of Antigen-Presenting Cells for Cancer Immunotherapy.
Small, 2015 Immunotherapeutic approaches for treating cancer overall have been receiving a considerable amount of interest due to the recent approval of several clinical formulations.
Ronnie H. Fang +2 more
semanticscholar +1 more source
Antigen Presentation by Spleen Dendritic Cells
Journal of Investigative Dermatology, 1985 It is now recognized that dendritic cells (DC) isolated from mouse spleen play an important role in activating T lymphocytes. These DC, which show many similarities to veiled cells found in the paracortical regions of spleen and lymph node, may be closely related to the epidermal Langerhans cells.
Geoffrey H. Sunshine, Tamara J. Mitchell
openaire +3 more sources