Regulation of T cell lymphokine production by killer cell inhibitory receptor recognition of self HLA class I alleles. [PDF]
The killer cell inhibitory receptors (KIRs) are surface glycoproteins expressed by natural killer (NK) and T cells that specifically recognize defined groups of polymorphic human histocompatibility leukocyte antigen (HLA) class I molecules.
Chang, C +3 more
core
An Effective Membrane Model of the Immunological Synapse
The immunological synapse is a patterned collection of different types of receptors and ligands that forms in the intercellular junction between T Cells and antigen presenting cells (APCs) during recognition.
Arup K. Chakraborty +8 more
core +1 more source
Animals bearing malignant grafts reject normal grafts that express through gene transfer the same antigen. [PDF]
Breaking the state of immunological unresponsiveness of tumor-bearing individuals to cancer is a prerequisite for active or passive tumor-specific immunotherapy.
Koeppen, H +5 more
core
Apoptosis Induced by Pseudomonas aeruginosa in Antigen Presenting Cells Is Diminished by Genetic Modification with CD40 Ligand [PDF]
S. WORGALL
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Strategies and delivery systems for cell-based therapy in autoimmunity
This review article explores the potential of engineering antigen-presenting cells (APCs) for the immunotherapy of autoimmune diseases. It discusses various strategies for modifying APCs to induce antigen-specific tolerance, thereby mitigating autoimmune
Matteo Puccetti +4 more
doaj +1 more source
APOBEC-related mutagenesis and neo-peptide hydrophobicity: implications for response to immunotherapy. [PDF]
Tumor-associated neo-antigens are mutated peptides that allow the immune system to recognize the affected cell as foreign. Cells carrying excessive mutation load often develop mechanisms of tolerance.
Boichard, Amélie +8 more
core
Thymocyte Development of Humanized Mice Is Promoted by Interactions with Human-Derived Antigen Presenting Cells upon Immunization [PDF]
Takataro Fukuhara +12 more
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Jeremiah Suryatenggara,1,2 Heri Wibowo,2 Wahyuni Lukita Atmodjo,3 George Mathew1,3 1Mochtar Riady Institute for Nanotechnology and Medical Science Group, Pelita Harapan University, Tangerang, 2Biomedical Science Graduate Programme, Faculty of Medicine ...
Suryatenggara J +3 more
doaj
Insulin‐like growth factor I messenger RNA and protein are expressed in the human lymph node and distinctly confined to subtypes of macrophages, antigen‐presenting cells, lymphocytes and endothelial cells [PDF]
Dominique Oberlin +2 more
openalex +1 more source
High Level Expression of MHC-II in HPV+ Head and Neck Cancers Suggests that Tumor Epithelial Cells Serve an Important Role as Accessory Antigen Presenting Cells [PDF]
Steven F. Gameiro +4 more
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