Dendritic cells and HIV transmission: roles and subsets of antigen-presenting cells in the human anogenital tract. [PDF]
Buffa DJ +9 more
europepmc +1 more source
HLA-DQ-restricted CD4+ T cells specific to streptococcal antigen present in low but not in high responders. [PDF]
Nobuhiro Kamikawaji +7 more
openalex +1 more source
Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia +20 more
wiley +1 more source
Diatom-Based Artificial Antigen-Presenting Cells: A Novel Approach for Adaptive Immune Modulation. [PDF]
Abdul Rahman A +3 more
europepmc +1 more source
Identification of a rabies virus T cell epitope on the basis of its similarity with a hepatitis B surface antigen peptide presented to T cells by the same MHC molecule (HLA-DPw4). [PDF]
Esteban Celis +3 more
openalex +1 more source
Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis
ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin +10 more
wiley +1 more source
Assessment of antigen immunogenicity formulated in minigenes transfected into antigen-presenting cells. [PDF]
Villota-Alava MA +4 more
europepmc +1 more source
Cholesterol Metabolism in Antigen-Presenting Cells and HIV-1 Trans-Infection of CD4+ T Cells. [PDF]
Okpaise D +3 more
europepmc +1 more source
Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages. [PDF]
Patrick G. Holt +6 more
openalex +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source

