Results 201 to 210 of about 2,473,811 (360)

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Assessment of antigen immunogenicity formulated in minigenes transfected into antigen-presenting cells. [PDF]

PLoS One
Villota-Alava MA, Alfaro-Marenco MA, Clavijo-Ramírez CA, Patarroyo MA, Parra-López CA.   +4 more
europepmc   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Sarcomatoid areas of urothelial carcinoma are enriched for CD163-positive antigen-presenting cells. [PDF]

J Pathol Clin Res
Johnson BA, Parimi V, Kamanda S, Corney DC, Choi W, Hoffman-Censits J, Kates M, McConkey DJ, Hahn NM, Matoso A.   +9 more
europepmc   +1 more source

Ewing Sarcoma Single-cell Transcriptome Analysis Reveals Functionally Impaired Antigen-presenting Cells. [PDF]

Cancer Res Commun, 2023
Visser LL, Bleijs M, Margaritis T, van de Wetering M, Holstege FCP, Clevers H.   +5 more
europepmc   +1 more source

Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages. [PDF]

, 1993
Patrick G. Holt, J. Oliver, N. Bilyk, Christine McMenamin, Paul G. McMenamin, Georg Kraal, Theo Thepen   +6 more
openalex   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells. [PDF]

, 1994
Michael Croft, Linda M. Bradley, Susan L. Swain   +2 more
openalex   +1 more source

Antigen-Presenting Intratumoral B Cells Affect CD4+ TIL Phenotypes in Non–Small Cell Lung Cancer Patients

Cancer immunology research, 2017
T. Bruno, Peggy J. Ebner, Brandon L. Moore, Olivia G. Squalls, Katherine A. Waugh, E. Eruslanov, S. Singhal, John D Mitchell, W. Franklin, D. Merrick, M. McCarter, B. Palmer, J. Kern, J. Slansky   +13 more
semanticscholar   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source