Results 291 to 300 of about 2,473,811 (360)

Towards efficient cancer immunotherapy: advances in developing artificial antigen-presenting cells

Trends in Biotechnology, 2014
L. Eggermont, L. Paulis, J. Tel, C. Figdor   +3 more
semanticscholar   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

FASTMAP-a flexible and scalable immunopeptidomics pipeline for HLA- and antigen-specific T-cell epitope mapping based on artificial antigen-presenting cells. [PDF]

Front Immunol
Weisbrod L, Capriotti L, Hofmann M, Spieler V, Dersch H, Voedisch B, Schmidt P, Knake S.   +7 more
europepmc   +1 more source

Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells.

Immunity, 2013
Yuting Ma, Sandy Adjemian, S. Mattarollo, T. Yamazaki, L. Aymeric, H. Yang, João Paulo Portela Catani, D. Hannani, Hélène Duret, Kim Steegh, I. Martins, F. Schlemmer, M. Michaud, O. Kepp, Abdul Qader Sukkurwala, Laurie Menger, Erika Vacchelli, N. Droin, L. Galluzzi, R. Krzysiek, S. Gordon, P. Taylor, P. van Endert, E. Solary, M. Smyth, L. Zitvogel, G. Kroemer   +26 more
semanticscholar   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Specific targeting of cancer vaccines to antigen-presenting cells via an endogenous TLR2/6 ligand derived from cysteinyl-tRNA synthetase 1. [PDF]

Mol Ther
Kim HY, Cho S, Kim SB, Song EC, Jung W, Shin YG, Suh JH, Choi J, Yoon I, Kim U, Ban H, Hwang S, Mun J, Park J, Kim N, Lee Y, Kim MH, Kim S.   +17 more
europepmc   +1 more source

CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation

, 1998
Hans Häcker, Harald Mischak, Thomas Miethke, Susanne Liptay, Roland M. Schmid, Tim Sparwasser, Klaus Heeg, Grayson B. Lipford, Hermann Wagner   +8 more
openalex   +2 more sources

Human cell‐based artificial antigen‐presenting cells for cancer immunotherapy

Immunological Reviews, 2014
M. Butler, N. Hirano
semanticscholar   +1 more source

Systematic Comparison of Commercial Uranyl‐Alternative Stains for Negative‐ and Positive‐Staining Transmission Electron Microscopy of Organic Specimens

Advanced Healthcare Materials, EarlyView.
Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling, Stephanie Eitner, Davide Bottone, Gea Cereghetti, Peter Wick   +4 more
wiley   +1 more source