Results 11 to 20 of about 3,953,720 (287)

Amelioration of collagen-induced arthritis using antigen-loaded dendritic cells modified with NF-κB decoy oligodeoxynucleotides

Drug Design, Development and Therapy, 2017
Hongmei Jiang,1 Henggui Hu,2 Yali Zhang,1 Ping Yue,3 Lichang Ning,1 Yan Zhou,1 Ping Shi,1 Rui Yuan1 1School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, Guizhou, 2Department of Clinical Laboratory, The Third Hospital Subsidiary ...
Jiang HM, Hu HG, Zhang YL, Yue P, Ning LC, Zhou Y, Shi P, Yuan R   +7 more
doaj   +1 more source

Studies on autoantigens in rheumatoid arthritis [PDF]

, 2003
This thesis describes the use of phage display for the isolation of autoantigens in rheumatoid arthritis. The potential of the technology is demonstrated by the isolation of an autoantigen, eukaryotic translation elongation factor 1a1 (eEF 1 (x 1) from a
Mewar, Devesh
core   +6 more sources

The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17–producing cellular network at multiple sites [PDF]

, 2012
Among many survival strategies, parasitic worms secrete molecules to modulate host immune responses. One such product, ES-62, is protective in the collagen-induced arthritis (CIA) model of rheumatoid arthritis.
Pineda, Miguel, Gracie, Alastair, McGrath, Mairi, Al-Riyami, Lamyaa, Rzepecka, Justyna, Harnett, Margaret, Smith, Pauline, Harnett, William   +7 more
core   +4 more sources

Liposomal targeting of prednisolone phosphate to synovial lining macrophages during experimental arthritis inhibits M1 activation but does not favor M2 differentiation. [PDF]

PLoS ONE, 2013
BACKGROUND: To determine the effects of liposomal targeting of prednisolone phosphate (Lip-PLP) to synovial lining macrophages on M1 and M2 polarization in vitro and during experimental arthritis. MATERIAL AND METHODS: Experimental arthritis (antigen and
Wouter Hofkens, Rik Schelbergen, Gert Storm, Wim B van den Berg, Peter L van Lent   +4 more
doaj   +1 more source

Fasciola hepatica extract suppresses fibroblast-like synoviocytes in vitro and alleviates experimental arthritis

Advances in Rheumatology, 2022
Background Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial inflammation, fibroblast-like synoviocytes (FLS) activation and joint destruction.
Suelen Pizzolatto Dalmolin, Renata Ternus Pedó, Thales Hein da Rosa, Jordana Miranda de Souza Silva, Mirian Farinon, Maria Luísa Gasparini, Eduardo Cremonese Filippi Chiela, Ana Helena Paz, Martín Pablo Cancela Sehabiague, Henrique Bunselmeyer Ferreira, Rafaela Cavalheiro do Espírito Santo, Fabiany da Costa Gonçalves, Ricardo Machado Xavier   +12 more
doaj   +1 more source

Pathological pathway analysis in an experimental rheumatoid arthritis model and the tissue repair effect of acupuncture at ST36

Frontiers in Immunology, 2023
Rheumatoid arthritis (RA) is an autoimmune disease that generally affects the joints. In the face of inflammation-induced cartilage and bone damage, RA treatment remains insufficient.
Yue Zhang, Hui Wang, Yi-Nan Gong, Yi-Nan Gong, Yi-Nan Gong, Fu-Ming Yang, Shen-Jun Wang, Shen-Jun Wang, Shen-Jun Wang, Yang-Yang Liu, Yang-Yang Liu, Yang-Yang Liu, Yong-Qing Gui, Fei Xie, Zhi-Fang Xu, Zhi-Fang Xu, Zhi-Fang Xu, Yi Guo, Yi Guo, Yi Guo   +19 more
doaj   +1 more source

Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis. [PDF]

PLoS ONE, 2016
Here, we investigate induction of immunological tolerance by lentiviral based gene therapy in a mouse model of rheumatoid arthritis, collagen II-induced arthritis (CIA).
Sara Tengvall, Tove Eneljung, Pernilla Jirholt, Olof Turesson, Kajsa Wing, Rikard Holmdahl, Jan Kihlberg, Anna Stern, Inga-Lill Mårtensson, Louise Henningsson, Kenth Gustafsson, Inger Gjertsson   +11 more
doaj   +1 more source

Distinct Roles of Vav Family Members in Adaptive and Innate Immune Models of Arthritis

Biomedicines, 2021
Genetic evidence suggests that three members of the VAV family (VAV1, VAV2 and VAV3) of signal transduction proteins could play important roles in rheumatoid arthritis.
Javier Conde, Isabel Fernández-Pisonero, Myriam Cuadrado, Antonio Abad, Javier Robles-Valero, Xosé R. Bustelo   +5 more
doaj   +1 more source

The effect of FK506 and cyclosporin A on antigen-induced arthritis [PDF]

Clinical and Experimental Immunology, 1991
SUMMARYFK506 and cyclosporin A inhibited the development of antigen-induced arthritis in the rat and rabbit. FK506 was five times more potent than cyclosporin A in the rat and approximately 20 times more potent in the rabbit. FK506 was effective in both species if administered either from the day of intra-articular administration or antigen or when the
A, Blackham, R J, Griffiths
openaire   +2 more sources

RNA sequencing data from osteochondroprogenitor populations in synovial joints of mice during murine model of rheumatoid arthritis

Data in Brief, 2020
The aim of this study was to analyze the transcriptome of TER119–CD31–CD45–CD51+CD200+CD105– population (further, CD200+), potential early osteocondroprogenitors, whose frequency is reduced in the joints of mice with antigen-induced arthritis (AIA) [1 ...
Nina Lukač, Vedran Katavić, Alan Šućur, Maša Filipović, Danka Grčević, Nataša Kovačić   +5 more
doaj   +1 more source