Results 31 to 40 of about 3,953,720 (287)

Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study. [PDF]

, 2015
INTRODUCTION: Neovascularization contributes to the development of sustained synovial inflammation in the early stages of Rheumatoid Arthritis. Ultrasound (US) provides an indirect method of assessing synovial blood flow and has been shown to correlate ...
Kelly, S, Maria DiCicco, Hands, RE, Frances Humby, Riahi, S, Nora Ng, Michele Bombardieri, Arti Mahto, Sudeh Riahi, Humby, F, DiCicco, M, Rebecca E Hands, Marrelli, A, Pitzalis, C, Stephen Kelly, Pyne, D, Lu Zou, Bombardieri, M, Mahto, A, Ng, N, Costantino Pitzalis, Zou, L, Debasish Pyne, Alessandra Marrelli   +23 more
core   +1 more source

EFFECT OF GLYCYRRHIZA GLABRA ON ANTIGEN INDUCED ARTHRITIS IN MICE MODEL

The Iraqi Journal of Medical Sciences
Background:Rheumatoid arthritis is a chronic inflammatory autoimmune disease represents the most common form of chronic inflammatory joint diseases. Glycyrrhiza glabra (G.
Abdulkareem H. Abd, Ban J. Qasim, Shihab A. Shihab, Jaffar O. Dawood   +3 more
doaj   +6 more sources

Folate Receptor Beta for Macrophage Imaging in Rheumatoid Arthritis

Frontiers in Immunology, 2022
Non-invasive imaging modalities constitute an increasingly important tool in diagnostic and therapy response monitoring of patients with autoimmune diseases, including rheumatoid arthritis (RA).
Maarten M. Steinz, Aiarpi Ezdoglian, Fatemeh Khodadust, Carla F. M. Molthoff, Madduri Srinivasarao, Philip S. Low, Gerben J. C. Zwezerijnen, Maqsood Yaqub, Wissam Beaino, Albert D. Windhorst, Sander W. Tas, Gerrit Jansen, Conny J. van der Laken   +12 more
doaj   +1 more source

TCRβ Sequencing Reveals Spatial and Temporal Evolution of Clonal CD4 T Cell Responses in a Breach of Tolerance Model of Inflammatory Arthritis

Frontiers in Immunology, 2021
Effective tolerogenic intervention in Rheumatoid Arthritis (RA) will rely upon understanding the evolution of articular antigen specific CD4 T cell responses. TCR clonality of endogenous CD4 T cell infiltrates in early inflammatory arthritis was assessed
Shaima Al Khabouri, Robert A. Benson, Catriona T. Prendergast, Joshua I. Gray, Thomas D. Otto, James M. Brewer, Paul Garside   +6 more
doaj   +1 more source

Modulation of Pristane-Induced Arthritis by Mycobacterial Antigens

Autoimmunity, 1991
Several prominent mycobacterial protein antigens involved in antibody and T cell responses have been identified as members of highly conserved heat shock protein families. In particular, immune responses to the mycobacterial 65 kD heat shock protein (hsp65) have been implicated in the pathogenesis of autoimmune diseases both in experimental animal ...
S J, Thompson, P D, Butcher, V K, Patel, G A, Rook, J, Stanford, R, van der Zee, C J, Elson   +6 more
openaire   +2 more sources

Locomotion and muscle mass measures in a murine model of collagen-induced arthritis [PDF]

, 2009
Background: Rheumatoid arthritis (RA) is characterized by chronic poly-arthritis, synovial hyperplasia, erosive synovitis, progressive cartilage and bone destruction accompanied by a loss of body cell mass.
Garssen, J., Judith Hulsman, Hulsman, J., Hartog, A., Johan Garssen, Anita Hartog   +5 more
core   +2 more sources

Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of IL-10-producing B cells and reduced plasma cell infiltration of the joints [PDF]

, 2014
We have previously reported that ES-62, a molecule secreted by the parasitic filarial nematode Acanthocheilonema viteae, protects mice from developing collagen-induced arthritis (CIA).
Al-Riyami, Lamyaa, Harnett, Margaret M., McGrath, Mairi A., Pineda, Miguel A., Rodgers, David T., Harnett, William   +5 more
core   +4 more sources

IL10- and IL35-Secreting MutuDC Lines Act in Cooperation to Inhibit Memory T Cell Activation Through LAG-3 Expression

Frontiers in Immunology, 2021
Dendritic cells (DCs) are professional antigen-presenting cells involved in the initiation of immune responses. We generated a tolerogenic DC (tolDC) line that constitutively secretes interleukin-10 (IL10-DCs), expressed lower levels of co-stimulatory ...
Marianna M. Koga, Adrien Engel, Matteo Pigni, Christine Lavanchy, Mathias Stevanin, Vanessa Laversenne, Bernard L. Schneider, Bernard L. Schneider, Hans Acha-Orbea   +8 more
doaj   +1 more source

MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis

Nature Communications, 2016
MiR-155 is thought to inhibit PU.1 and thereby drive antigen-induced B-cell maturation. Here the authors show that patients with rheumatoid arthritis have high B-cell miR-155 expression and that an antagomir can rescue PU.1 expression, suggesting ...
Stefano Alivernini, Mariola Kurowska-Stolarska, Barbara Tolusso, Roberta Benvenuto, Aziza Elmesmari, Silvia Canestri, Luca Petricca, Antonella Mangoni, Anna Laura Fedele, Clara Di Mario, Maria Rita Gigante, Elisa Gremese, Iain B. McInnes, Gianfranco Ferraccioli   +13 more
doaj   +1 more source

Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1

The Journal of Clinical Investigation, 2022
CD13, an ectoenzyme on myeloid and stromal cells, also circulates as a shed, soluble protein (sCD13) with powerful chemoattractant, angiogenic, and arthritogenic properties, which require engagement of a G protein–coupled receptor (GPCR).
Pei-Suen Tsou, Chenyang Lu, Mikel Gurrea-Rubio, Sei Muraoka, Phillip L. Campbell, Qi Wu, Ellen N. Model, Matthew E. Lind, Sirapa Vichaikul, Megan N. Mattichak, William D. Brodie, Jonatan L. Hervoso, Sarah Ory, Camila I. Amarista, Rida Pervez, Lucas Junginger, Mustafa Ali, Gal Hodish, Morgan M. O’Mara, Jeffrey H. Ruth, Aaron M. Robida, Andrew J. Alt, Chengxin Zhang, Andrew G. Urquhart, Jeffrey N. Lawton, Kevin C. Chung, Tristan Maerz, Thomas L. Saunders, Vincent E. Groppi, David A. Fox, M. Asif Amin   +30 more
doaj   +1 more source