Results 151 to 160 of about 1,150,441 (351)
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
Improved antigen cross-presentation by polyethyleneimine-based nanoparticles
International Journal of Nanomedicine, 2011 Jian Chen1, Zhengrong Li1, Hong Huang2, Yanzhu Yang2, Qian Ding2, Junhua Mai1, Wei Guo2, Yuhong Xu21School of Life Sciences and Biotechnology, 2School of Pharmacy, Shanghai Jiao Tong University, Shanghai, People's Republic of ChinaPurpose: In the
Jian Chen +3 more
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Expression of MHC II genes [PDF]
Current topics in microbiology and immunology. 290 (2005) Pages
147-70, Accession Number 16480042, 2006 Innate and adaptive immunity are connected via antigen processing and presentation (APP), which results in the presentation of antigenic peptides to T cells in the complex with the major histocompatibility (MHC) determinants. MHC class II (MHC II) determinants present antigens to CD4+ T cells, which are the main regulators of the immune response. Their
arxiv
Antigen presentation by EBV-B cells to resting and activated T cells: role of interleukin 1. [PDF]
, 1985 E T Chu +4 more
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ETEC colonization factors modulate the antigen presentation function of porcine intestinal mononuclear phagocytes [PDF]
, 2013 C
Baert, Kim +4 more
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Molecular Oncology, EarlyView.Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim +8 more
wiley +1 more source
Defective antigen presentation by human melanoma cell lines cultured from advanced, but not biologically early, disease. [PDF]
, 1989 Michael Alexander +2 more
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Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
Robust Control of a Brain-Persisting Parasite through MHC I Presentation by Infected Neurons
Cell Reports, 2019 Summary: Control of CNS pathogens by CD8 T cells is key to avoid fatal neuroinflammation. Yet, the modalities of MHC I presentation in the brain are poorly understood.
Anna Salvioni +10 more
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