Results 161 to 170 of about 532,042 (312)

The impact of antigen presentation on BBB disruption and neuroinflammation. [PDF]

Physiology (Bethesda)
Maynes MA, Johnson AJ.
europepmc   +1 more source

Efficient antigen presentation [PDF]

Nature Biotechnology, 1999
openaire   +2 more sources

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Artificial Antigen Presenting Cells With Preclustered anti-CD28/-CD3/-LFA-1 Monoclonal Antibodies Are Highly Effective To Induce The Ex-Vivo Expansion Of Functional Human Antitumor T Cells

, 2007
Effective adoptive T cell therapy requires the _ex vivo_ generation of functional T lymphocytes with a long lifespan _in vivo_. We evaluated _in vitro_ T cell expansion by artificial antigen presenting cells (aAPC) generated with activating (human anti ...
Roberta Zappasodi, Carmelo Carlo-Stella, Lorena Passoni, Salvatore Albani, Claudia Vegetti, Massimo Di Nicola, Alessandro M. Gianni, Roberta Mortarini, Alessandra Molla, Andrea Anichini   +9 more
core  

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Allelic variation alters expression and antigen presentation of MR1 allomorphs. [PDF]

J Biol Chem
Nelson AG, Letoga V, Lee CZQ, Samer C, Li S, Meehan LJ, McWilliam HEG, Gherardin NA, Abendroth A, Villadangos JA, Slobedman B, Corbett AJ, McCluskey J, Rossjohn J, Chen Z, Souter MNT, Awad W.   +16 more
europepmc   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Whole-genome doubling drives immune evasion by silencing antigen presentation. [PDF]

Cancer Cell
Foidart P, Li Z, Cai X, Seehawer M, Brown DD, Tawawalla A, Baldominos P, Parvin S, Nishida J, Rojas-Jimenez E, Bui TM, Diciaccio B, Kumar R, Schlegel BT, Goyette MA, Scales T, Yan P, Qiu X, Li R, Jiang Y, Xie Y, Aarabi M, Huang XY, Stevens LE, Cejas P, Mangiante L, Sotomayor Vivas CI, Houlahan KE, Curtis C, Oesterreich S, Harris IS, Letai AG, Lee AV, Long HW, Agudo J, Polyak K.   +35 more
europepmc   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Endogenous human cytomegalovirus gB is efficiently presented by MHC class II molecules to CD4+ CTL

, 2005
Human cytomegalovirus (HCMV) infects endothelial, epithelial, and glial cells in vivo. These cells can express MHC class II proteins, but are unlikely to play important roles in priming host immunity.
Nelson, JA, Dunn, C, Johnson, DC, Hegde, NR, Lewinsohn, DM, Jarvis, MA   +5 more
core