We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei+6 more
wiley +1 more source
A synthetic cyclic peptide for promoting antigen presentation and immune activation. [PDF]
Zhang J+15 more
europepmc +1 more source
The role of polymorphic HLA-DR beta chain residues in presentation of viral antigens to T cells. [PDF]
Robert W. Karr+4 more
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ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren+8 more
wiley +1 more source
AMPK-dependent Parkin activation suppresses macrophage antigen presentation to promote tumor progression. [PDF]
Wang X+25 more
europepmc +1 more source
Glycosyl-phosphatidylinositol-anchored and transmembrane forms of CD46 display similar measles virus receptor properties: virus binding, fusion, and replication; down-regulation by hemagglutinin; and virus uptake and endocytosis for antigen presentation by major histocompatibility complex class II molecules [PDF]
G Varior-Krishnan+4 more
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ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu+6 more
wiley +1 more source
Antigen presentation of post-translationally modified peptides in major histocompatibility complexes. [PDF]
de Wit AS, Bianchi F, van den Bogaart G.
europepmc +1 more source
Presentation of human minor histocompatibility antigens by HLA-B35 and HLA-B38 molecules. [PDF]
Johtaro Yamamoto+4 more
openalex +1 more source