Results 191 to 200 of about 3,030,865 (307)

Antigen processing and presentation an overview

Memorias do Instituto Oswaldo Cruz, 1992
Soren Buus
doaj   +1 more source

Targeting TOMM40 unleashes immunogenic mitophagy to facilitate antigen presentation and immunotherapy sensitization. [PDF]

J Immunother Cancer
Zhang Z, Xie YA, Mu C, Sheng S, Zhang J, Han J, Li J, He Z, Liu X.   +8 more
europepmc   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

Melanoma in people living with HIV: antigen-presentation loss, spatial immune escape, and inclusive immunotherapy trials. [PDF]

Front Immunol
Giubellino A, Mansini AP.
europepmc   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

High-mobility group N proteins are required for regulation of antigen-presentation genes in macrophages. [PDF]

J Immunol
Oh KS, Babagana M, Chakraborty S, Aqdas M, Pacholewska A, Dahiya D, Bustin M, Sung MH.   +7 more
europepmc   +1 more source

“Activation‐Resistance Elimination” Regulation by Lanthanide/Transition Metal Ion‐Coordinated Nanostructures Intensifies Cuproptosis and Tumor Immunotherapy

Advanced Materials, EarlyView.
The lanthanide/transition metal ion coordination nanoparticles, La‐Cu@Lap/IWR‐1, with optimized coordination, have been proven to achieve remarkable results in realizing comprehensive tumor cuproptosis through efficient cuproptosis activation and multidimensional resistance elimination, thereby synchronously realizing the synergistic antitumor effects ...
Junrong Wang, Mengqian Xu, Huaping Zhao, Yulin Xie, Guoqing Zhu, Haoze Li, Qianqian Sun, Yong Lei, Chunxia Li   +8 more
wiley   +1 more source

Correction: Plasticity and antigen presentation by group 3 innate lymphoid cells in colorectal cancer. [PDF]

Front Immunol
Qiao L, Zhang J, Li J, Li X, He X, Zhang M, Lu J, Zhang X, Dong J, Tao G, Wang Y, Cui J, Bao L, Zhao P.   +13 more
europepmc   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

Lineage plasticity and immune invisibility in primary SCLC and LUAD-to-SCLC transformation: antigen presentation loss and therapeutic redirection. [PDF]

Front Immunol
Xu H, Li B, Yang J, Tang X.
europepmc   +1 more source