Results 221 to 230 of about 3,243,106 (373)

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Lymphodepleting chemotherapy potentiates neoantigen-directed T cell therapy by enhancing antigen presentation. [PDF]

Cell Rep Med
Sagie S, Babu T, Weller C, Tabachnik C, Livneh I, Quast NP, Gumpert N, Shomuradova A, Raybould MI, Levy R, Malko D, Alfia A, Ben Lulu T, Alon M, Herrera F, Kutuzov M, Zerbib M, Greenberg P, Wasserman-Bartov T, Benedek G, Levin Y, Stossel C, Kamer I, Golan T, Oren R, Shmueli M, Bartok O, Bar J, Cohen J, Dushek O, Deane CM, Samuels Y.   +31 more
europepmc   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Cmss1 limits FMDV infection by enhancing antigen presentation and CD8⁺ T cell responses. [PDF]

J Virol
Wang Y, Zhang L, Deng J, Zheng L, Chen Z, Zhang Z, Zhang H, Pei J, Zheng H.   +8 more
europepmc   +1 more source

Biomimetic polyelectrolyte microparticles facilitate antigen presentation by porcine dendritic cells [PDF]

, 2012
Baert, Kim, Cox, Eric, De Geest, Bruno, Devriendt, Bert, Dierendonck, Marijke, Favoreel, Herman, Remon, Jean Paul   +6 more
core   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

<i>Brucella</i> Immune Escape: TLR Subversion, Antigen Presentation Destruction and T Cell Disorder. [PDF]

Cells
Jiao H, Zhou G, Wu S, Meng C, Wang L, Fan C, Li J, Chu Y.   +7 more
europepmc   +1 more source

The Cytosolic Endopeptidase, Thimet Oligopeptidase, Destroys Antigenic Peptides and Limits the Extent of MHC Class I Antigen Presentation [PDF]

, 2003
Ian A. York, Annie X. Mo, Kristen Lemerise, Wanyong Zeng, Yuelei Shen, Carmela R. Abraham, Tomo Šarić, Alfred L. Goldberg, Kenneth L. Rock   +8 more
openalex   +1 more source

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

Epigenetic control of antigen presentation failure in osteosarcoma: from single-cell chromatin maps to therapeutic strategies. [PDF]

Front Immunol
He Y, Wu H.
europepmc   +1 more source