Results 231 to 240 of about 688,457 (330)

Continuous CD8 ⁺ T-Cell Priming by Dendritic Cell Cross-Presentation of Persistent Antigen following Adeno-Associated Virus-Mediated Gene Delivery [PDF]

, 2011
Dan Xu, Christopher M. Walker
openalex   +1 more source

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

Advanced Functional Materials, EarlyView.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz, Pablo Varela, Laura del‐Mazo‐Barbara, Irene Lodoso‐Torrecilla, Emilio Jiménez‐Piqué, Jordi Franch, Miguel Alaminos, Maria‐Pau Ginebra   +7 more
wiley   +1 more source

IFN-γ-driven UBE2D3 upregulation impairs antigen presentation pathways and anti-tumor immunity in pancreatic cancer. [PDF]

Nat Commun
Wang S, Yang W, Peng T, Zhu C, Dong J, Wang Y, Yuan H, Sun Q, Luan X, Guan X, Zhang W, Qin JJ.   +11 more
europepmc   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Massively parallel immunopeptidome by DNA sequencing provides insights into cancer antigen presentation. [PDF]

Nat Genet
Shi Q, Simon EP, Cimen Bozkus C, Kaminska A, Velazquez L, Saxena M, Zhang Z, Belk JA, Wang S, Yang N, Zhang Y, Kwong A, Che Y, Stickels RR, Crain CR, Schmidt-Hong L, Lichti CF, Gaiha GD, Roth TL, Bhardwaj N, Satpathy AT, Yu B, Chang HY.   +22 more
europepmc   +1 more source

Dendritic cell maturation and antigen presentation in the absence of invariant chain

, 1998
Patrizia Rovere, Valérie S. Zimmermann, Frédérique Forquet, Denis Demandolx, Jeannine Trucy, Paola Ricciardi‐Castagnoli, Jean Davoust   +6 more
openalex   +2 more sources

Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions

Advanced Functional Materials, EarlyView.
An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park, Dong‐yup Lee, Sungsoo Lim, JangHyuk Kim, Min‐Gyu Lee, Chang Seo Park, Hyeonuk Na, Yong Eun Cho, Yun Hyeok Lee, Junsang Doh, Jeong‐Yun Sun   +10 more
wiley   +1 more source

Asymmetric Dimethylarginine Disrupts Tumor Antigen Presentation in Breast Cancer. [PDF]

Int J Mol Sci
Li M, Chen YL, Pearce LM, Hammett AM, Sharma FH, Miller DS, Chen KE.   +6 more
europepmc   +1 more source

Sec61 in antigen cross-presentation

, 2015
Matthias Zehner, Sven Burgdorf
openalex   +1 more source

A Self‐Curling Si3N4‐Biofunctionalized Nerve Wrap for Suture‐Free Peripheral Nerve Repair with Multimodal Regenerative Bioregulation

Advanced Functional Materials, EarlyView.
Si3N4‐enhanced bioactive nanostructured adhesive wrap enables rapid conduit formation in wet environments, simplifying surgical procedures. Incorporated Si3N4 undergoes controlled hydrolysis within nanofibers, multi‐directionally modulating the peripheral nerve repair microenvironment for effective suture‐free repair.
Pengchao Ma, Yihao Liu, Bowen Ren, Chun‐Yi Yang, Xiaobin Luo, Peilun Hu, Jia Yang, Zheng Cao, Keya Mao, Jianheng Liu, Xiumei Wang   +10 more
wiley   +1 more source