Results 141 to 150 of about 368,728 (306)
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
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Antigen Presenting Cells [PDF]
, 2005 Preface. List of Contributors. List of Abbreviations. Color Plates. Part I: Antigen Presentation in the Immune System. 1 Some Old and Some New Findings on Antigen Processing and Presentation (Emil R. Unanue). 1.1 Introduction. 1.2 HEL Processing. 1.3 Selection of Peptide Segments of HEL. 1.4 HEL: Conformational Isomers.
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FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
, 2008 It is just forty years since the identification of immunoglobulin E (IgE) as the reagin responsible for allergen induced immediate hypersensitivity reactions.
Sihra, Bhupinder Singh
core
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
In vitro studies on T cell proliferation and Lymphokine factor production in the amphibian, Xenopus [PDF]
, 1990 The major aim of this Thesis has been to procure and begin to characterise T cell-derived cytokines in the clawed toad, Xenopus. Recent reports have suggested that Xenopus lymphocytes, stimulated in vitro with T cell mitogens, will generate factors that ...
Turner, Sarah Louise
core
Co-Stimulatory Functions of Antigen-Presenting Cells
, 1992 Antigen-presenting cells, in addition to presenting processed antigen, provide co-stimulatory signals that are necessary for stimulating maximal lymphokineproduction by CD4+ T cells.
Jenkins, Marc K, Johnson, Julia G
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FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Antigen presentation by B cells [PDF]
Nature, 1989 K, Bottomly, C A, Janeway
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