Results 31 to 40 of about 19,444,475 (370)

The Antigen Processing and Presentation Machinery in Lymphatic Endothelial Cells

Frontiers in Immunology, 2019
Until a few years ago, lymphatic vessels and lymphatic endothelial cells (LEC) were viewed as part of a passive conduit for lymph and immune cells to reach lymph nodes (LN).
L. Santambrogio, Stella J. Berendam, V. Engelhard   +2 more
semanticscholar   +1 more source

Current Concepts of Antigen Cross-Presentation

Frontiers in Immunology, 2018
Dendritic cells have the ability to efficiently present internalized antigens on major histocompatibility complex (MHC) I molecules. This process is termed cross-presentation and is important role in the generation of an immune response against viruses ...
Maria Embgenbroich, Sven Burgdorf
doaj   +1 more source

Carbohydrate receptor-mediated gene transfer to human T leukaemic cells [PDF]

, 1994
The mucin-type carbohydrate Tn cryptantigen (GalNAcα1-O-Ser/Thr, where GalNAc is N-acetyl-D-galactosamine) is expressed in many carcinomas, in haemopoietic disorders including the Tn syndrome, and on human immunodeficiency virus (HIV) coat glycoproteins,
Berger, Eric G., Birnstiel, Max L., Clausen, Henrik, Cotten, Matt, Dinter, André, Mechtler, Karl, Rusconi, Sandro, Thurnher, Martin, Wagner, Ernst   +8 more
core   +2 more sources

The yin/yang balance of the MHC-self-immunopeptidome

Frontiers in Immunology, 2022
The MHC-self immunopeptidome of professional antigen presenting cells is a cognate ligand for the TCRs expressed on both conventional and thymic-derived natural regulatory T cells.
Laura Santambrogio, Alessandra Franco
doaj   +1 more source

Poly(2-propylacrylic acid)/poly(lactic-co-glycolic acid) blend microparticles as a targeted antigen delivery system to direct either CD4+ or CD8+ T cell activation. [PDF]

, 2017
Poly(lactic-co-glycolic acid) (PLGA) based microparticles (MPs) are widely investigated for their ability to load a range of molecules with high efficiency, including antigenic proteins, and release them in a controlled manner.
Bracho-Sanchez, Evelyn, Carstens, Matthew R, Duvall, Craig L, Fernando, Lawrence P, Keselowsky, Benjamin G, Lewis, Jamal S, Yang, Lirong   +6 more
core   +1 more source

How ERAP1 and ERAP2 Shape the Peptidomes of Disease-Associated MHC-I Proteins

Frontiers in Immunology, 2018
Four inflammatory diseases are strongly associated with Major Histocompatibility Complex class I (MHC-I) molecules: birdshot chorioretinopathy (HLA-A*29:02), ankylosing spondylitis (HLA-B*27), Behçet's disease (HLA-B*51), and psoriasis (HLA-C*06:02). The
José A. López de Castro
doaj   +1 more source

Main Components of Fish Immunity: An Overview of the Fish Immune System

Fishes, 2023
Cellular immune responses consist of innate and adaptive cell-mediated immune mechanisms, where all leukocyte subpopulations are included. Among these are vital processes such as cell-mediated cytotoxicity and phagocytosis. The main cellular constituents
Doaa M. Mokhtar, Giacomo Zaccone, Alessio Alesci, Michal Kuciel, Manal T. Hussein, Ramy K. A. Sayed   +5 more
doaj   +1 more source

Stage-Specific Inhibition of MHC Class I Presentation by the Epstein-Barr Virus BNLF2a Protein during Virus Lytic Cycle [PDF]

, 2009
gamma-herpesvirus Epstein-Barr virus (EBV) persists for life in infected individuals despite the presence of a strong immune response. During the lytic cycle of EBV many viral proteins are expressed, potentially allowing virally infected cells to be ...
A Rickinson, AD Hislop, AD Hislop, Alan B. Rickinson, Andrew D. Hislop, Andrew I. Bell, B Park, Bill Sugden, BJ Biegalke, BN Lilley, C Bogedain, Claire Shannon-Lowe, Daniëlle Horst, DJ Tenney, E Scotet, Elisabeth Kremmer, Emmanuel J. H. J. Wiertz, G Lautscham, HJ Delecluse, J Yuan, J Zuo, J Zuo, Jaap M. Middeldorp, JC Stinchcombe, JW Yewdell, JX Zhang, K Takada, L Young, LS Young, M Buisson, M Kishishita, M Rowe, Maaike E. Ressing, Martin Rowe, MC Gold, ME Ressing, MT Vossen, MW Munks, Nathan P. Croft, NM Steven, P Rivailler, PG Stevenson, R Feederle, S Keating, TA Groothuis, TR Jones, TR Jones, V Bohm, VA Pudney, WM van Grunsven, X Saulquin, Y Zeng   +51 more
core   +7 more sources

Epigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinoma

Scientific Reports, 2017
Merkel cell carcinoma (MCC) is a rare and aggressive, yet highly immunogenic skin cancer. The latter is due to its viral or UV-associated carcinogenesis. For tumor progression MCC has to escape the host’s immuno-surveillance, e.g.
Cathrin Ritter, Kaiji Fan, A. Paschen, Sine Reker Hardrup, S. Ferrone, P. Nghiem, S. Ugurel, D. Schrama, J. Becker   +8 more
semanticscholar   +1 more source

Evidence for a nuclear compartment of transcription and splicing located at chromosome domain boundaries [PDF]

, 1993
The nuclear topography of splicing snRNPs, mRNA transcripts and chromosome domains in various mammalian cell types are described. The visualization of splicing snRNPs, defined by the Sm antigen, and coiled bodies, revealed distinctly different ...
A Monneron, A Schneider-G�dicke, AK Raap, B Roggenbuck, C Benyajati, C Collins, C Cremer, C Zorn, CA Ascoli, D Pinkel, D Pinkel, DE Comings, DJ Arndt-Jovin, DL Spector, DL Spector, DL Spector, DL Spector, DL Spector, DM Shotton, EA Lerner, G Blobel, GJ Brakenhoff, HTM Voort Van der, I Raska, J Bradl, JB Lawrence, JD Northway, JG Gall, JR Paulson, KC Carter, L Manuelidis, L Manuelidis, L Manuelidis, L Manuelidis, LEC Andrade, M Bachmann, M Bouteille, M Carmo-Fonseca, M Carmo-Fonseca, M Carmo-Fonseca, M Carmo-Fonseca, M Hochstrasser, M Mattioli, M Schardin, N Hutchison, P Lichter, P Lichter, P Lichter, P Lichter, R Berezney, R Reuter, R Verheijen, S Fakan, S Fakan, S Huang, SA Berman, T Cremer, T Cremer, TM Jovin, U Bond, U Nyman, Y Hiraoka, y Ramon, Y Xing, Y Xing   +64 more
core   +1 more source