Results 1 to 10 of about 1,337,759 (297)

Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions

Advanced Functional Materials, EarlyView.
An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park, Dong‐yup Lee, Sungsoo Lim, JangHyuk Kim, Min‐Gyu Lee, Chang Seo Park, Hyeonuk Na, Yong Eun Cho, Yun Hyeok Lee, Junsang Doh, Jeong‐Yun Sun   +10 more
wiley   +1 more source

Label‐Free and Low‐Power Driven Cancer Biomarker Detection Enabled by 2D Hexagonal Titanium Oxide

Advanced Functional Materials, EarlyView.
A low‐power driven FET biosensor based on 2D hexagonal TiO2 detects the cancer biomarker carcinoembryonic antigen with high sensitivity, a low detection limit of 0.22 pg mL−1, and excellent selectivity. Leveraging the unique electronic properties of the material, this work demonstrates strong potential for integration into miniature and portable cancer
Yange Luan, Qijie Ma, Yihong Hu, Xinyi Hu, Guanyu Chen, Jiaru Zhang, Zhong Li, Dongdong Xie, Guanghui Ren, Yunyi Yang, Guifu Ding, Kate Fox, Bao Yue Zhang, Jian Zhen Ou   +13 more
wiley   +1 more source

Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME

Advanced Functional Materials, EarlyView.
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li, E Pang, Snehasish Debnath, Jia Hong, Aojun Qiu, Dongeun Kim, Goeun Kim, Minhuan Lan, Min‐Goo Lee, Qian‐Yong Cao, Jong Seung Kim   +10 more
wiley   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Emerging 2D Materials and Their Hybrid Nanostructures for Label‐Free Optical Biosensing: Recent Progress and Outlook

Advanced Functional Materials, EarlyView.
This review highlights recent advances in label‐free optical biosensors based on 2D materials and rationally designed mixed‐dimensional nanohybrids, emphasizing their synergistic effects and novel functionalities. It also discusses multifunctional sensing platforms and the integration of machine learning for intelligent data analysis.
Xinyi Li, Yonghao Fu, Yuehe Lin, Dan Du
wiley   +1 more source

Tumor‐associated antigens: Tn antigen, sTn antigen, and T antigen

HLA, 2016
AbstractGlycosylation is one of the major posttranslational modifications of proteins. N‐glycosylation (Asn‐linked) and O‐glycosylation (Ser/Thr‐linked) are the two main forms. Abnormal O‐glycosylation is frequently observed on the surface of tumor cells, and is associated with an adverse outcome and poor prognosis in patients with cancer.
C. Fu, H. Zhao, Y. Wang, H. Cai, Y. Xiao, Y. Zeng, H. Chen   +6 more
semanticscholar   +3 more sources

The Bennett‐ Goodspeed Antigen or Antigens

Vox Sanguinis, 1963
SummaryMany sera used in blood grouping contain a second antibody. Not infrequently this belongs to what appears to be a family of antibodies called variously anti‐Donna, anti‐Sturgeon, anti‐Ho, anti‐Bennett‐Goodspeed, anti‐Price, etc. The reactions with the sera are not always reproducible. The antigen was found in 7 out of 158 unrelated parents. In 5
Hiroko Kaita, B. Chown, Marion Lewis
openaire   +4 more sources

Pillars Article: The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

Journal of Immunology, 2005
Most of the polymorphic amino acids of the class I histocompatibility antigen, HLA-A2, are clustered on top of the molecule in a large groove identified as the recognition site for processed foreign antigens. Many residues critical for T-cell recognition
Pamela J. Bjorkman, M. Saper, B. Samraoui, W. S. Bennett, J. Strominger, D. Wiley   +5 more
semanticscholar   +1 more source

The Haakestad Antigen Is Identical with the Hov Antigen

Vox Sanguinis, 1987
Abstract. The rare blood group antigen previously referred to as the ‘Haakestad antigen’ is shown to be identical with the Hov antigen (numerical designation: 700.038). Family studies add ABO and HLA to the systems already known to segregate independently from Hov. Among 2,021 Danish blood donors, 4 Hov+ persons were found.
Donald Jerne, L. Kornstad, Patricia Tippett   +2 more
openaire   +3 more sources

Nature of the antigenic determinants of T locus antigens

Cell, 1980
The nature of the antigenic specificities of several antigens associated with the T/t complex in the mouse were analyzed by means of glycosidase and haptene inhibition studies. Results indicate that on testicular cells sugar residues are involved in at least six different T/t antigenic determinants.
Cheng, C C, Bennett, D
openaire   +3 more sources