Results 1 to 10 of about 884,279 (321)
Immunoprotection against Cryptococcosis Offered by Znf2 Depends on Capsule and the Hyphal Morphology
mBio, 2022 Systemic cryptococcosis is fatal without treatment. Globally, this disease kills 180,000 of the 225,000 infected people each year, even with the use of antifungal therapies. Currently, there is no vaccine to prevent cryptococcosis.
Jianfeng Lin +5 more
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Mathematical Modeling Insights into Improving CAR T cell Therapy for Solid Tumors: Antigen Heterogeneity and Bystander Effects [PDF]
npj Systems Biology and Applications, 10(1), 105 (2024), 2023 As an adoptive cellular therapy, Chimeric Antigen Receptor T-cell (CAR T-cell) therapy has shown remarkable success in hematological malignancies, but only limited efficacy against solid tumors. Compared with blood cancers, solid tumors present a unique set of challenges that ultimately neutralize the function of CAR T-cells.
arxiv +1 more source
Annals of Clinical Microbiology, 2022 Background: We evaluated the diagnostic performance of the Exdia COVID-19 antigen test (Exdia Ag; Precision Biosensor Inc., Korea) as a point-of-care (POC) test performed in the emergency department (ED) for the rapid detection of severe acute ...
In Young Yoo +5 more
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Journal of Applied Veterinary Sciences, 2020 The standard serological test such as Rose Bengal Plate Test (RBPT) is routinely used for the diagnosis of brucellosis. This test depends on the agglutination of colored particulate antigen (killed Brucella organisms) by the antibodies present in sera ...
Lamees A. El-Tantawy +3 more
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Frontiers in Immunology, 2021 Aspergillus fumigatus causes life-threatening opportunistic infections in immunocompromised patients. As therapeutic outcomes of invasive aspergillosis (IA) are often unsatisfactory, the development of targeted immunotherapy remains an important goal ...
Lukas Page +21 more
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Protocol for T-cell Adhesion Strength on Tumor Cells under Flow Conditions
Bio-Protocol, 2013 This method allows evaluating the relative adhesion strength between T lymphocytes and specific adherent target cells using a shear force in flow chambers.
Marie Boutet +3 more
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The role of antigen-competitive dynamics in regulating the immune response [PDF]
Bulletin of Mathematical Biology, 83(5): 40 (2021), 2021 The clonal expansion of T cells during an infection is tightly regulated to ensure an appropriate immune response against invading pathogens. Although experiments have mapped the trajectory from expansion to contraction, the interplay between mechanisms that control this response are not fully understood.
arxiv +1 more source
Immunophenotypic Aberrancies in Acute Leukemia: A Tertiary Care Centre Experience
Oman Medical Journal, 2021 Objectives: Acute leukemias (AL) are a heterogeneous group of hematological malignancies with the presence of 20% or more blasts in the peripheral blood or bone marrow.
Monika Gupta +5 more
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The onset of occupational diseases in mushroom cultivation and handling operators: a review
Italian Journal of Mycology, 2019 The paper presents a review on health hazards involving operators that cultivate and handle mushrooms. Intensive production of edible and medicinal fungi is a common agricultural management all over the world and involves a number of operators whose ...
Barbara Ficociello +4 more
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ICAMs Are Not Obligatory for Functional Immune Synapses between Naive CD4 T Cells and Lymph Node DCs
Cell Reports, 2018 Protective immune responses depend on the formation of immune synapses between T cells and antigen-presenting cells (APCs). The two main LFA-1 ligands, ICAM-1 and ICAM-2, are co-expressed on many cell types, including APCs and blood vessels.
Sara W. Feigelson +12 more
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