Blood, 1997 The tumor marker carcinoembryonic antigen (CEA) belongs to a family of proteins which are composed of one immunogiobulin variable domain and a varying number of immunoglobulin constant-like domains.
Goyert, S. +13 more
core +11 more sources
A Characterization of the Humoral Immune Response to Human Endogenous Retroviruses and Mycobacterium paratuberculosis in Crohn’s Disease [PDF]
PathogensCrohn’s disease (CD) is a multifactorial polygenic inflammatory bowel disease linked to aberrant immune response. Mycobacterium paratuberculosis (MAP) has been associated with CD; however, detecting MAP in CD tissues remains highly challenging. Recently,
Alishba Fayyaz +5 more
doaj +2 more sources
Disease-specific B cell clones are shared between patients with Crohn’s disease [PDF]
Nature CommunicationsB cells have important functions in gut homeostasis, and dysregulated B cell populations are frequently observed in patients with inflammatory bowel diseases, including both ulcerative colitis (UC) and Crohn’s disease (CD). How these B cell perturbations
Prasanti Kotagiri +20 more
doaj +2 more sources
High number of CD14+B7H4+ monocytes is significantly associated with increased concentrations of IL-4, IL-13, IL-10, and TGF-β1 in tumor microcirculation of lung carcinoma [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. Lung cancer (LC) is one of the leading causes of mortality. Disease progression and advanced disease are characterized by the unprotective immune response due to M2 macrophage polarization, myeloid-derived suppressor cells (MDSC) activity,
Vuković Jelena +8 more
doaj +1 more source
Non-Toxin-Based Clostridioides difficile Vaccination Approaches
Pathogens, 2023 Clostridioides difficile (CD) is a Gram-positive, anaerobic bacterium that infects mainly hospitalized and elderly people who have been treated with long-term antibiotic therapy leading to dysbiosis.
Agnieszka Razim +2 more
doaj +1 more source
Specific IgG response against Mycobacterium avium paratuberculosis in children and adults with Crohn's disease. [PDF]
PLoS ONE, 2013 Background and aimsPresence of serum antibodies against Mycobacterium avium paratuberculosis (MAP) in Crohn's Disease (CD) as a disease characteristic remains controversial.
Julien Verdier +13 more
doaj +1 more source
PLoS Neglected Tropical Diseases, 2022 BackgroundChagas disease (CD) is caused by Trypanosoma cruzi. The chronic phase of CD is characterized by the presence of IgG anti-T. cruzi antibodies; and diagnosis is performed by serological methods.
Ramona Tavares Daltro +10 more
doaj +1 more source
Heat shock protein-derived T-cell epitopes contribute to autoimmune inflammation in pediatric Crohn's disease. [PDF]
PLoS ONE, 2009 Pediatric Crohn's disease is a chronic auto inflammatory bowel disorder affecting children under the age of 17 years. A putative etiopathogenesis of Crohn's disease (CD) is associated with disregulation of immune response to antigens commonly present in ...
Gisella L Puga Yung +11 more
doaj +1 more source
Primary stromal sarcoma of the breast [PDF]
Archive of Oncology, 2012 Primary sarcomas of the breast are rare and there are only a few hundred cases reported in the literature; hence, their significance is primarily educational.
Radovanović Aleksandra +3 more
doaj +1 more source
Parasites & Vectors, 2022 Background Chagas disease (CD) is caused by Trypanosoma cruzi, which is transmitted mainly through the feces/urine of infected triatomine bugs. The acute phase lasts 2–3 months and is characterized by high parasitemia and nonspecific symptoms, whereas ...
Natália Erdens Maron Freitas +9 more
doaj +1 more source