Results 41 to 50 of about 5,310 (124)

Amplified Sensitivity in SERS Detection of L1CAM With Silver Plasmonic Mesoporous Silica Capsules on an Imprinted Films

Advanced Materials Interfaces, EarlyView.
This study presents core‐shell Au‐Ag NPs and a novel molecularly imprinted polymer (MIP)‐based material targeting L1CAM. Thionine is used as a monomer to create the MIP on a carbon screen‐printed electrode. Functionalized Au‐AgNCs with Raman reporter 4‐mercaptobenzoic acid and anti‐L1CAM enable selective detection via surface‐enhanced Raman scattering ...
Yuselis Castaño‐Guerrero, Belén Arjones‐Fernández, Felismina T.C. Moreira, Ramon A. Alvarez‐Puebla, Miguel A. Correa‐Duarte, H. Águas, M. Goreti F. Sales   +6 more
wiley   +1 more source

The use of quantum dots to amplify antigen detection [PDF]

arXiv, 2017
Proposal to develop an Improved immunological assay employing primary IgG antibodies and secondary IgM antibodies labeled with quantum dots to amplify antigen detection.
arxiv  

Microneedles with Interdigitated Electrodes for In Situ Impedimetric VEGF Sensing

Advanced Materials Interfaces, EarlyView.
An electrochemical device for transdermal monitoring based on flexible polylactide microneedles with interdigitated electrodes enables continuous monitoring of vascular endothelial growth factor (VEGF) in interstitial fluid. Gold‐coated microneedles functionalized with anti‐VEGF antibodies, provide an in situ detection platform with high sensitivity ...
Ritu Das, Emin Istif, Rumeysa Cebecioglu, Mohsin Ali, Yasin Atik, Çağdaş Dağ, Eda Celikbas, Gozde Demirci, FundaYagcı Acar, Murat Hasanreisoğlu, Levent Beker   +10 more
wiley   +1 more source

Multi‐omics analyses reveal the interaction between colonic microbiota and host in Min and Yorkshire pigs

Animal Research and One Health, EarlyView., 2023
In the present study, we created the weight gain models with Min and Yorkshire pigs and conducted the metagenomics and metabolomics of colon contents and transcriptomics of colon tissue. Further, we revealed the characteristics and functions of the colonic microbiota in Min and Yorkshire pigs and analyzed their interactions with the host. Overall, this
Xiaoyu Huang, Huihui Li, Feng Cheng, Ligang Wang, Guoqing Cao, Lixian Wang, Lijun Shi   +6 more
wiley   +1 more source

Canalization of the evolutionary trajectory of the human influenza virus [PDF]

arXiv, 2011
Since its emergence in 1968, influenza A (H3N2) has evolved extensively in genotype and antigenic phenotype. Antigenic evolution occurs in the context of a two-dimensional 'antigenic map', while genetic evolution shows a characteristic ladder-like genealogical tree. Here, we use a large-scale individual-based model to show that evolution in a Euclidean
arxiv  

Evaporation‐Enhanced Redox Cycling for Rapid Detection of Attomolar SARS‐CoV‐2 Virions Using Nanolithography‐Free Electrochemical Devices

Advanced Materials Technologies, EarlyView.
This study presents microfabricated electrochemical sensors for detecting ultralow viral particles counts through evaporation‐enhanced redox cycling (E2RC). To achieve sub‐micrometer gap in interdigitated microelectrodes, a scalable, nanolithography‐free fabrication method is developed.
Pouya Soltan Khamsi, Vinay Kammarchedu, Aida Ebrahimi   +2 more
wiley   +1 more source

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

Advanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin, Houxin Fan, Zhenchao Liu, Paolo Donati, Youssef Amin, Yap Wing Fen, Junbo Liang, Pier Paolo Pompa, Sailing He   +8 more
wiley   +1 more source

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source

Developing a consensus statement for psychosocial support in active surveillance for prostate cancer

BJUI Compass, Volume 4, Issue 1, Page 104-113, January 2023., 2023
Abstract Purpose Our objective was to prioritise the psychosocial support needs of men on active surveillance for prostate cancer and to develop a consensus statement to provide guidance on best practice psychosocial support for men choosing active surveillance and their families.
Kerri Beckmann, Declan Cahill, Christian Brown, Mieke Van Hemelrijck, Netty Kinsella   +4 more
wiley   +1 more source

HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou, Yan Guo, Shuang Xu, Mi Bai, Weidong Cao, Yue Zhang, Zhanjun Jia, Aihua Zhang   +7 more
wiley   +1 more source