Results 171 to 180 of about 231,458 (256)

Immunological Microenvironment Diversity in Homogeneous and Non-Homogeneous Oral Leukoplakia. [PDF]

Int J Mol Sci
Čēma I, Kleina R, Dzudzilo M, Lasiené K, Dabužinskiene A, Muceniece J, Zolovs M, Freivalds T.   +7 more
europepmc   +1 more source

ANTI-CD20 AGENTS RESHAPE THE PHENOTYPE AND FUNCTIONS OF CYTOTOXIC LYMPHOCYTES AND SELECTIVELY MITIGATE EBV-SPECIFIC CD8+ T CELL REACTIVITY IN PEOPLE WITH RELAPSING MULTIPLE SCLEROSIS

Anti-CD20 therapy with ocrelizumab is highly effective in relapsing multiple sclerosis (RMS), but its mechanisms extend beyond B-cell depletion. In a prospective study of 41 RMS patients, we longitudinally assessed CD8+ T cells and NK cells using flow ...
ABBADESSA, GIANMARCO
core  

Neurodegenerative Diseases: Epidemiology, Risk Factors, Classification, Pathophysiology, Clinical Features, Diagnosis, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He, Jingjing Zeng, Guoqing Wang, Yuxin Li, Feng Zhang   +4 more
wiley   +1 more source

Circulating Extracellular Vesicle Biomarkers in Chronic Lymphocytic Leukemia: A Preliminary Study on Their Diagnostic, Prognostic, and Predictive Relevance. [PDF]

Biomolecules
Laurenzana I, Caivano A, Di Ciancia A, Villani O, Maietti M, De Stradis A, D'Arena G, Nozza F, De Luca L, Lamorte D.   +9 more
europepmc   +1 more source

Dedifferentiation in endometrial cancer is associated with HLA‐I silencing that may be restored by IFN‐γ

The Journal of Pathology, Volume 270, Issue 3, Page 317-327, November 2026.
Abstract Dedifferentiated endometrial carcinoma occurs when a prognostically favorable low‐grade endometrial carcinoma transforms into a highly aggressive undifferentiated carcinoma following genomic inactivation of core SWItch/Sucrose Non‐Fermentable (SWI/SNF) complex protein(s).
Antonio De Leo, Madison Wickenberg, Marco Grillini, Camelia Alexandra Coadǎ, Pooja Praveen Kumar, Annie Tong, James Key, Hannah Kim, Felix Kommoss, Mark Carey, Yangxin Fu, Claudio Ceccarelli, Giovanni Tallini, Paul LaPointe, Martin Köbel, Cheng‐Han Lee   +15 more
wiley   +1 more source

CD20 bispecific T-cell engager depletes B-cell progenitors preventing EBV-associated lymphomagenesis in humanized mice. [PDF]

Blood Adv
Böni M, Schuhmachers P, von Boxberg S, Poon A, Thevenon E, Mennonna D, Ramones M, Romann L, Walter SL, Fennell É, Rucci F, Traggiai E, Münz C.   +12 more
europepmc   +1 more source

Multiple Sclerosis and Viruses: « Liaisons Dangereuses »

Reviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Samanta Plavina, Daniela Malakovska, Jolanta Kalnina, Ilva Trapina, Elina Leonova, Mohammed Habib, Susanne Schifmann, Jegors Paramonovs, Nikolajs Sjakste, Yegor Vassetzky, Emmanuel Drouet, Natalia Paramonova   +11 more
wiley   +1 more source

Expansion Microscopy Reveals the Spatial Association of Therapeutic Antibody–Receptor Complexes With Cholesterol‐Rich Membrane Domains

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
We report a super‐resolution strategy that maps cholesterol‐rich membrane domains in whole, intact cells with an effective spatial resolution of ∼40 nm by combining expansion microscopy with a perfringolysin O domain 4 probe. This approach enables direct visualization of the spatial association between CD20 and CD38 complexes and cholesterol‐rich ...
Gang Wen, Nicole Seifert, Patrick Eiring, Johanna Meyer, Hannes Neuweiler, Julia Weingart, Ignacio Vega‐Vásquez, Sören Doose, Philip Kollmannsberger, Markus Sauer   +9 more
wiley   +2 more sources

Programmable CAR and antigen pairing for solid tumor immunotherapy. [PDF]

Mol Ther Oncol
Huang Z, Wang Y.
europepmc   +1 more source

Anaplastic cutaneous plasmacytoma in a dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract Extramedullary cutaneous plasmacytoma is an uncommon tumour in dogs and rare in cats, often linked to chronic inflammation or prolonged antigenic stimulation. It typically affects middle‐aged to older dogs, involving the head, trunk, limbs and digits.
André Castilhano Marcelino Silva, Júlia Kaori Hayashi, Danielle Cavalcanti Carvalho de Diniz, Maria Lucia Gomes Lourenço, Luiz Henrique Araujo de Machado   +4 more
wiley   +1 more source