Daratumumab combined with anti-CD20 therapy in pediatric and adult refractory idiopathic nephrotic syndrome: single-center experience. [PDF]
Naciri Bennani H +8 more
europepmc +1 more source
Duales Targeting von malignen B-Zellen mit einem bispezifischen chimären Antigen-Rezeptor (CAR) zur Erkennung von Antigen-Verlustvarianten [PDF]
Martyniszyn, Alexandra
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'Immune reset plus': the case for combining immunotherapies to maintain self-tolerance in autoimmune diseases. [PDF]
Gaspal F +4 more
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CD5<sup>+</sup> primary hepatosplenic large B-cell lymphoma and rhupus syndrome in a patient: a case of concurrent diagnosis? [PDF]
Lin S, Yin J, Zhang Z, Wang X.
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B lymphocytes and tertiary lymphoid structures have a prognostic impact on penile squamous cell carcinoma. [PDF]
Zavillová N +8 more
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Ofatumumab and Granzyme B as immunotoxin against CD20 antigen
In Silico Pharmacology, 2022Anti-CD20 antibodies such as ofatumumab has demonstrated efficacy in relapsed/refractory chronic lymphocytic leukemia, are among the most successful therapies to date. In this study, we have designed an immunotoxin composed of Granzyme B and the high affinity variant of Ofatumumab.
Fateme Sefid +6 more
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CD20 is a potential target for immunotherapy treatments of haematological malignancies due to its specific expression and unique biological property. Over the years, many anti-CD20 monoclonal antibodies (mAbs) have been developed, such as Rituximab, Ibritumomab, Tositumomab, etc., and applied in B cells related to cancer treatments.
Nguyen Thanh Thao Vo +4 more
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Development of a Mimotope-Based Vaccine Against CD20 Antigen
Protein & Peptide Letters, 2007CD20, a B-cell-specific protein, is a primary target for immunotherapy of B-cell lymphomas. We used a mimotopes of CD20 to construct vaccines for B-cell-related disorders. The immunogenicity of the vaccines was tested in BALB/c mice. Results of this study suggest that the mimotope may be a useful tool for the construction of a functional vaccine to ...
Meng, Li +5 more
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CD20: A target antigen for immunotherapy of autoimmune diseases
Autoimmunity Reviews, 2005This article reviews the role of CD20 antigen in B cell function and the effectiveness and limits of passive immunotherapy with anti-CD20 monoclonal antibody (Rituximab) in the treatment of autoimmune (or immune-mediated) diseases. Active immunotherapy is a more feasible way to control these chronic diseases.
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