Results 171 to 180 of about 101,429 (314)

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

Advanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi, Jingrui Cao, Tong Wu, Guang Yang, YaWen Yang, Shixin Zhang, Wenwen Su, Hongyu Chu, Yangyang Zhao, Shan Jiang, Qiong Wu, Dongxu Jiao, Fangfang Chen   +12 more
wiley   +1 more source

Regulation of the maternal immune system during early bovine pregnancy. [PDF]

Reprod Fertil
Thornton AE, Rutigliano HM.
europepmc   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

The role of intestinal microbiota in the pathogenesis of childhood asthma. [PDF]

Front Immunol
Zhang L, Wu L, Shi C, Huang Q, Zhan L, Zeng Y, Deng Q.   +6 more
europepmc   +1 more source

Regulatory T cell control of anti-tumour responses

, 2008
One of the main obstacles to immunotherapy of cancer in humans is the immunosuppressive environment that surrounds the tumour mass, preventing any effective immune response from halting or reversing the threat of the tumour. Thus the observations in Balb/
Malcolm, Timothy I.M.
core  

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Exploring Autologous Dendritic Cells for T Cell Modulation: A Step Towards Personalized Medicine in Leishmaniasis. [PDF]

Cells
Meunier M, Valério-Bolas A, Rodrigues A, Fróis-Martins F, Ferreira R, Cardoso I, Monteiro M, Palma-Marques J, Carvalheiro M, Nunes T, Antunes WT, Alexandre-Pires G, Pereira da Fonseca I, Santos-Gomes G.   +13 more
europepmc   +1 more source

Mechanisms of Pericyte‐Mediated Cancer Metastasis

Advanced Science, EarlyView.
Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Ziheng Guo, Yihai Cao
wiley   +1 more source

The biological characteristics of tertiary lymphoid structures in head and neck cancer. [PDF]

Front Immunol
Bai S, Wei Y, Liu F, Sun H, Zeng X, Zhang P.   +5 more
europepmc   +1 more source

Generation of effector cells from T cell subsets [PDF]

, 1979
Koszinowski, Ulrich H., Simon, M. M.
core