Results 171 to 180 of about 156,998 (310)

Generation of virus specific cytotoxic T cells in vitro [PDF]

, 1979
Greber, D., Koszinowski, Ulrich H., Neuschaefer-Rube, I.   +2 more
core  

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

The roles and heterogeneity of CD8⁺ T cells in inflammatory bowel disease: A narrative review of insights from single‑cell transcriptomics (Review). [PDF]

Int J Mol Med
Zhong R, Guo J, Ye W, Deng Z, Wu H, Qi Q, Li G, Zhu L, Huang Y, Wu L.   +9 more
europepmc   +1 more source

Detection of autoantibodies against thyroglobulin, thyroid microsomes, and other soluble antigens with a rational and economical immunoblotting microtechnique [PDF]

, 1985
Berndt, H., Finkbeiner, H., Geusendam, G., Gutekunst, R., Scriba, Peter Christian, Stöcker, W.   +5 more
core   +1 more source

Cryoablation Activates the cGAS–STING‐CXCL10 Axis in Macrophages to Enhance Anti‐Tumor Immunity in NSCLC

Advanced Science, EarlyView.
Tumor dsDNA released by cryoablation is taken up by macrophages, activating the cGAS‐STING signaling pathway. This leads to an expansion of the CXCL10+ macrophage pool and increased secretion of CXCL10, which in turn recruits CXCR3+ T cells from draining lymph nodes into the tumor microenvironment to exert anti‐tumor effects.
Xinxin Zhi, Zhengcao Xing, Libo Luo, Jiale Wang, Xinyu Liu, Jia Yu, Jizhong Yin, Bin Chen, Yiwei Liu, Hui Sun, Guanghui Gao, Lei Wang, Xiaoxia Chen, Fei Li, Hu Ma, Lin Wang, Shuo Yang, Shengxiang Ren   +17 more
wiley   +1 more source

Immune Mechanisms in Myocardial Remodeling Following Myocardial Infarction: Focusing on Regulatory Networks of T Cell Responses. [PDF]

J Inflamm Res
Guo W, Li H, Wang Z, Wang Z, Liu A, Wang X, Tang Q, Li H.   +7 more
europepmc   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

The dual role of T cells in solid organ transplant rejection and immune tolerance. [PDF]

Front Immunol
Zhang Z, Zhao N, Miao Y, Sun Y, Liu C, Cao N, Liu C, Ding Y, Li J, Li N.   +9 more
europepmc   +1 more source

A Mitochondria‐Specific Nanomedicine for Synergistic Chemo‐Photothermal Therapy and Immunogenic Activation Against Breast Cancer

Advanced Science, EarlyView.
Peptide dendrimer–based nanoplatform with mitochondria‐targeting capability was developed for synergistic chemo‐photothermal therapy. The system promotes efficient transcytosis, induces mitochondrial dysfunction, triggers immunogenic cell death (ICD), and enhance antitumor immunity by promoting dendritic cell maturation and T‐cell activation, resulting
Min Li, Jiangqi Feng, Junyang Zhuang, Qingguo Zhong, Yanda Li, Yanzhuo Lv, Shaoteng Huang, Xiangyu Huang, Mingbo Zhang, Xiaofeng Cai, Yuxin Wang, Wenping Chen, Zhenyu Duan, Zhou Chen, Kui Luo, Ning Li   +15 more
wiley   +1 more source

Thymic epithelial tumors at the crossroads of immunity, autoimmunity, and immunotherapy. [PDF]

Cancer Immunol Immunother
Canaslan K, Moeini Nia F, Baez M, Abolhassani H, Ridge N, Bou Zerdan M, Marks J, Rangoonwala H, Jahanbin B, Emami AH, O'Reilly K, Gökmen-Polar Y, Badve SS, Xu C, Hao Y, Sharma A, Upadhya S, Galateau Salle F, Pan K, El Olsta B, Shin DM, Ardeshir-Larijani F.   +21 more
europepmc   +1 more source