Results 241 to 250 of about 214,371 (284)

Differentiation antigens expressed predominantly on CD4− CD8− T lymphocytes (WC1, WC2)

Veterinary Immunology and Immunopathology, 1991
Abstract The 14 mAbs representing workshop cluster 1 recognise a 215 300 kDa antigen expressed on a subpopulation of lymphocytes which express low levels of CD5 but are negative for other B and T cell markers defined by workshop antibodies. Separate studies with cDNA probes for bovine CD3 and T cell receptor indicate that these lymphocytes ...
W.I. Morrison, W.C. Davis
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Human T Lymphocyte Differentiation Antigens as Target for Immunotoxins or Complement‐Mediated Cytotoxicity

Scandinavian Journal of Immunology, 1988
Graft‐versus‐host disease (GVHD) after allogeneic hone marrow transplantation (BMT) is initiated by immunocompetent T fells present in the graft. Selective elimination of distinct T‐cell subsets or a sufficient, but not complete T‐cell depletion, might abolish severe GVHD without graft rejection and loss of the anti‐tumour potential.
F W, Preijers, T, De Witte, G P, Rijke-Schilder, W J, Tax, J M, Wessels, C, Haanen, P J, Capel   +6 more
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Clonal expression of differentiation and Ia‐like antigens on alloreactive human T lymphocytes

European Journal of Immunology, 1984
AbstractA series of human T lymphocyte clones showing specific responses for major histocompatibility complex‐encoded alloantigens were isolated from a single culture. They were classified into distinct functional groups based on measurement of alloantigen‐specific proliferation and cytotoxicity.
D J, Schendel, J P, Johnson, R L, Evans, R, Wank   +3 more
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INDUCTION OF HUMAN T-LYMPHOCYTE DIFFERENTIATION ANTIGENS

1976
Publisher Summary This chapter presents a summarization of the results of an analysis of human T-lymphocyte differentiation antigens (HTLAs) demonstrating the existence of human T-lymphocyte differentiation antigens, their induction on precursor cells by thymic factors, and the application of this methodology to the investigation of immunodeficiency ...
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Role of Macrophage D-Region Antigens and T-Lymphocyte Differentiation Antigens in Induction of Gamma Interferon

Journal of Interferon Research, 1985
Macrophage-T-lymphocyte cultures from patients with recent recurrent herpes labialis were stimulated to produce gamma interferon by either herpes simplex antigen or mitogens (PHA and Con A). The ability of monoclonal antibodies to HLA-DR and DC/DS, HSV glycoprotein antigens and T-lymphocyte surface antigens to inhibit interferon production and ...
A L, Cunningham, T Y, Basham, M F, Para, T C, Merigan   +3 more
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Cutaneous T-cell lymphoma, multilobated type, expressing membrane differentiation antigens of precursor T-lymphocytes

British Journal of Dermatology, 1982
Monoclonal antibodies to human T-cell membrane antigens were used to evaluate the immunological phenotype of the tumour cells in two cases of a recently described cutaneous T-cell lymphoma of 'multilobated' type. In one case the distinctive abnormal blast cells expressed positivity for OKT6, anti-HTAI, OKT4 and Leu-3a, and showed binding capacity for ...
S C, van der Putte, H J, Schuurman, J, Toonstra   +2 more
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[Antigen recognition and differentiation of T lymphocytes].

Hematology and cell therapy, 1998
During their intrathymic development, T lymphocytes acquire the ability to recognize myriads of antigens bound to self major histocompatibility molecules. This property is linked to the activation at early stages of thymic development of the biosynthesis of the antigen recognition receptors, the T cell receptors.
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Human "null" cells mediating antibody-dependent cellular cytotoxicity express T lymphocyte differentiation antigens.

The Journal of Immunology, 1980
Abstract There is considerable controversy regarding the cell lineage of killer (K) or effector cells in ADCC isolated from the “null” cell subpopulation (ER-sIg-) in human blood. Null cells were examined for the presence of T cell antigens by using a fluorescein-conjugated anti-T cell xenoantiserum (AMT).
C M, Balch, E W, Ades, M R, Loken, S L, Shore   +3 more
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Structural identity between HLA-A2 antigens differentially recognized by alloreactive cytotoxic T lymphocytes.

The Journal of Immunology, 1991
Abstract Alloreactive CTL raised against HLA-A2 Ag often display heterogeneous recognition of HLA-A2+ target cells. This heterogeneity has been found to reflect structural polymorphism among the corresponding target Ag, thus defining HLA-A2 subtypes. A previous study (van der Poel et al. 1986. Human Immunol.
A R, Castaño, P, Lauzurica, N, Domenech, J A, López de Castro   +3 more
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Differential Ras signaling via the antigen receptor and IL-2 receptor in primary T lymphocytes

Biochemical and Biophysical Research Communications, 2003
Ras can become activated via multiple distinct receptors in T lymphocytes. However, mechanistic studies of Ras signaling in normal T cells have been hampered by the lack of an efficient technology for gene transfer into resting post-thymic cells. We have overcome this limitation by utilizing adenoviral transduction of T cells from Coxsackie/adenovirus ...
Marks, Reinhard, Ho, Allen W, Rivas, Fabiola, Marshall, Emily, Janardhan, Sujit, Gajewski, Thomas F.   +5 more
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