Results 231 to 240 of about 11,845,318 (301)

Paradoxes of Immunity: Alternative Forms of Adaptive Immunity Discovered by Evolutionary Genomics. [PDF]

Acta Naturae
Shilov ES, Nedospasov SA.
europepmc   +1 more source

A Bi‐Adjuvant Senolytic Nanovaccine Modulating Dendritic Cell Senescence Ameliorates Aging‐Related Metabolic Dysfunction

Advanced Science, EarlyView.
An active biomaterial‐based bi‐adjuvant nanovaccine restores the immunocompetence of aged dendritic cells to overcome senescent cell tolerance. Accompanied by the downregulation of mitotic kinases Aurka/b and attenuation of senescence‐associated PI3K/AKT phosphorylation, the nanovaccine enhances antigen‐presenting capacity and promotes potent cytotoxic
Qingxu Song, Xiaoxue Du, Wenbo Dong, Ying Wang, Xiaojing Wang, Qiliang Yin   +5 more
wiley   +1 more source

The brain's immune code: decoding antigen presentation at the meningeal-glymphatic interface in neurological disorders. [PDF]

Front Immunol
Li W, Liang Y, Li L, Sun H, Liu Q.
europepmc   +1 more source

Topology‐Driven X‐Shaped DNA as a cGAS Stimulator to Promote Dendritic Cell Activation and Antitumor Vaccine Efficacy

Advanced Science, EarlyView.
X‐shaped DNA promotes multivalent cGAS assembly and enhances cGAS‐STING signaling. When conjugated with antigenic peptides, the resulting X‐DNA‐based peptide vaccine promotes dendritic cell activation, antigen presentation, and antitumor T‐cell responses.
Jiabei Li, Xuan Wang, Dali Wei, Zhejie Chen, Ziyi Wang, Qing Yu, Yu Yang, Shengpeng Wang   +7 more
wiley   +1 more source

The Role of Chimeric Antigen Receptor Regulatory T Cells in Promoting Immune Tolerance in Solid Organ Transplantation: <i>Mechanisms and Therapeutic Potential</i>. [PDF]

Saudi Med J
Alwethaynani MS.
europepmc   +1 more source

CD86‐Positive Mature Tertiary Lymphoid Structures Are Associated With CD8+ T‐Cell Infiltration and Favorable Clinical Outcomes in Pancreatic Ductal Adenocarcinoma

Annals of Gastroenterological Surgery, EarlyView.
CD86‐positive mature tertiary lymphoid structures were associated with increased intratumoral CD8+ T‐cell infiltration, a higher proportion of Granzyme B‐expressing CD8+ T cells in an exploratory analysis, and favorable clinical outcomes in pancreatic ductal adenocarcinoma.
Takaomi Seki, Kenichiro Araki, Takehiko Yokobori, Hayato Ikota, Norio Kubo, Takamichi Igarashi, Mariko Tsukagoshi, Norihiro Ishii, Yasuo Hosouchi, Hiroshi Saeki, Ken Shirabe   +10 more
wiley   +1 more source

Novel EG95-based mRNA vaccines induce long-term protective immunity against echinococcosis. [PDF]

PLoS Pathog
Chen WG, Li L, Dai GD, Wu YD, Zhu CG, Zhang H, Li XR, Li L, Zhang NZ, Wang LQ, Li GC, Ma WL, Pan JT, Tan ML, Da FL, Yin H, Fu BQ, Luo XN, Yan HB, Jia WZ.   +19 more
europepmc   +1 more source

Immune cell interactions and lung damage in SARS-CoV-2 special attention on monocytes/macrophages, T and B lymphocytes, dendritic cells and Toll-like receptors in SARS-CoV-2. [PDF]

Am J Clin Exp Immunol
Gulubova MV, Ignatova MK, Dimitrova DN, Ananiev JR.   +3 more
europepmc   +1 more source

Cold and hot tumors: immunological determinants, cancer-immunity cycle dysregulation, and nanotechnology-driven therapeutic approaches. [PDF]

Mol Biomed
Teiama MS, Gohar A, Amr M, El-Shinawi M, Elkhatib WF.   +4 more
europepmc   +1 more source