Results 221 to 230 of about 156,998 (310)

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

Initiation of Tertiary Lymphoid Structures for Cancer Immunotherapy. [PDF]

Research (Wash D C)
Zou JY, Li ZT, Wang ZC, Li H, Sun ZJ.
europepmc   +1 more source

The organ transplanted patient - immunological concepts and immunosuppression [PDF]

, 1991
Husberg, BS, Klintmalm, GBG, Starzl, TE
core  

Reprogramming Antitumor Immunity: NK Cell Strategies to Navigate the Immunosuppressive Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumor immune escape is a major barrier to durable cancer immunotherapy, as advanced malignancies create a tumor microenvironment (TME) that preferentially exhausts and disables T cell responses. While most approved cell therapies are T cell‐based, this limitation motivates the exploration of an alternative effector cell platform.
Tereza Kochs, Pranay Nath, Alice Chen, Rizwan Romee, Andreia Maia   +4 more
wiley   +1 more source

A cocktail vaccine with monkeypox virus antigens confers protection without selecting mutations in potential immune evasion genes in the vaccinia WR strain challenge. [PDF]

mBio
Sun X, Zhang L, Chen G, Yang F, Ning X, Qiu J, Gao Y, Yang J, Zhang W, Zhang Z, Zhang Y, Li S, Zeng M, Fu B, Li Y, Peng C, Li W.   +16 more
europepmc   +1 more source

Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair

Advanced Science, EarlyView.
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li, Xin Xing, Beicheng Du, Myles Zhou, Austin Z. Chen, Mary Archer, Chunbao Rao, Manyu Zhu, Masnsen Cherief, Aaron W. James   +9 more
wiley   +1 more source

The Class I Scavenger Receptors CD5 and CD6 Play a Role in the Early Peritoneal Immune Response to <i>Echinococcus granulosus</i> Tegumental Antigens. [PDF]

Int J Mol Sci
García-Luna J, Català C, Dematteis S, Lozano F, Velasco-De-Andrés M, Mourglia-Ettlin G.   +5 more
europepmc   +1 more source

Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang, Ning Lu, Zhuo Yan, Luyi Ye, Luyao Bai, Shanshan Yuan, Yuting Zhu, Yiru Xiong, Yongheng Bai, Yaping Chen, Junjie Deng   +10 more
wiley   +1 more source

A Phenome-Wide Association and Mendelian Randomization Study of Genetically Predicted Membranous Nephropathy with Multiple Diseases.

Kidney Blood Press Res
Wenghaerbai A, Alemasi A, Gu L, Deng J, Zhou Y.   +4 more
europepmc   +1 more source

CD4⁺ T cells in cancer: dual roles, exhaustion, and therapeutic breakthroughs. [PDF]

Cancer Biol Med
Zhang Y, Xu J, Pan S, Wang Y, Zhao Q, Huang Z, Hu C, Cheng X.   +7 more
europepmc   +1 more source