Results 81 to 90 of about 101,429 (314)

Human T lymphocyte differentiation antigens: Effects of blood sample storage on LEU antibody binding [PDF]

Cytometry, 1983
AbstractCurrent studies of human T lymphocytes and their subsets often use quantitative immunofluorescence analysis with monoclonal antibodies against cell surface antigens. With storage of whole blood or separated mononuclear cells for more than a few hours we have found marked changes in lymphocyte analysis using a fluorescence activated cell sorter (
P A, Hensleigh, V B, Waters, L A, Herzenberg   +2 more
openaire   +2 more sources

Diagnostic Use of Testing for Novel Murine Autoantibodies for Sjögren Disease in the Rheumatology Outpatient Setting

Arthritis Care &Research, EarlyView.
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr, Michael D. George, Vatinee Y. Bunya, Nora Sandorfi, Mina Massaro‐Giordano, Frederick B. Vivino   +5 more
wiley   +1 more source

Advances and prospects in tumor infiltrating lymphocyte therapy

Discover Oncology
Tumor-infiltrating lymphocyte (TIL) therapy in adoptive T-cell therapy (ACT) has already caused durable regression in a variety of cancer types due to T-cell persistence, clinical activity, and duration of objective response and safety. TILs are composed
Xu Qiu, Shengjun Li, Tianyu Fan, Yue Zhang, Bin Wang, Bei Zhang, Mingzhe Zhang, Li Zhang   +7 more
doaj   +1 more source

Endothelial cells as targets for antigen-specific cytotoxic T lymphocytes [PDF]

, 2010
BACKGROUND: In this study we have examined human vascular endothelial cells as targets for antigen-specific cytotoxic T lymphocytes (CTL). Vascular endothelial cells (EC) act as the major interface between blood and tissues and are crucial for the ...
Thommen, Daniela Stefanie
core   +1 more source

Effect of ageing on CMV-specific CD8 T cells from CMV seropositive healthy donors

Immunity & Ageing, 2009
Background Ageing is associated with changes in the immune system with substantial alterations in T-lymphocyte subsets. Cytomegalovirus (CMV) is one of the factors that affect functionality of T cells and the differentiation and large expansions of CMV ...
Alonso Corona, Casado Javier G, DelaRosa Olga, Gayoso Inmaculada, Pita-Lopez María, Muñoz-Gomariz Elisa, Tarazona Raquel, Solana Rafael   +7 more
doaj   +1 more source

Influence of murine mesenchymal stem cells on proliferation, phenotype, vitality, and cytotoxicity of murine cytokine-induced killer cells in coculture. [PDF]

PLoS ONE, 2014
Stimulating lymphocytes with Ifn-γ, anti-CD3, and interleukin-2 promotes the proliferation of a cell population coexpressing T-lymphocyte surface antigens such as CD3, CD8a, and CD25 as well as natural killer cell markers such as NK1.1, CD49, and CD69 ...
Martin Bach, Christoph Schimmelpfennig, Alexandra Stolzing   +2 more
doaj   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

The role of SAP in antigen priming and differentiation of T lymphocytes

, 2016
Mutations in the SH2D1A gene that encodes signaling lymphocyte activation molecule (SLAM)-associated protein (SAP) cause X-linked lymphoproliferative disease (XLP), a congenital immunodeficiency defined by exquisite sensitivity to Epstein-Barr virus (EBV).
openaire   +1 more source

Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells [PDF]

, 2007
Interactions between antigen-presenting dendritic cells (DCs) and T cells are essential for the induction of an immune response. However, during malaria infection, DC function is compromised and immune responses against parasite and heterologous antigens
Owain R Millington, Bernd H. Zinselmeyer, Zinselmeyer Bernd H, Brewer James M, Paul Garside, Rush, Catherine M., Rush, C.M., Owain R. Millington, Millington, O.R., Vivienne B Gibson, Catherine M. Rush, Bernd H Zinselmeyer, Rush, C., R. Stephen Phillips, Gibson, V.B., Vivienne B. Gibson, Phillips, R.S., R Stephen Phillips, Catherine M Rush, Zinselmeyer, B.H., Millington, Owain R., Brewer, James M., Gibson Vivienne B, Millington Owain R, Brewer, J.M., Gibson, Vivienne B., Phillips R. Stephen, Garside Paul, Rush Catherine M, Phillips, R. Stephen, Zinselmeyer, Bernd H., Garside, P., James M. Brewer, Garside, Paul, James M Brewer   +34 more
core   +1 more source