Results 31 to 40 of about 1,437,318 (308)

Dectin-1-triggered Recruitment of Light Chain 3 Protein to Phagosomes Facilitates Major Histocompatibility Complex Class II Presentation of Fungal-derived Antigens*

Journal of Biological Chemistry, 2012
Background: Dectin-1 is a phagocytic receptor important for host immune responses to fungal infections. Results: Dectin-1 signaling directs LC3 to phagosomes leading to increased MHC class II recruitment and increased presentation of fungal-derived ...
Jun Ma, Courtney A. Becker, C. Lowell, D. Underhill   +3 more
semanticscholar   +1 more source

Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance A newly discovered system for immunological detection of diverse bacterial and fungal pathogens involves the MHC-like host protein called MR1. This molecule scavenges metabolites from the biosynthesis of riboflavin by microbes.
Hamish E. G. McWilliam, Jeffrey Y. W. Mak, W. Awad, Matthew Zorkau, S. Cruz-Gomez, H. Lim, Yuting Yan, Sam Wormald, Laura F. Dagley, S. Eckle, A. Corbett, Haiyin Liu, Shihan Li, Scott J. J. Reddiex, J. Mintern, Ligong Liu, J. McCluskey, J. Rossjohn, D. Fairlie, J. Villadangos   +19 more
semanticscholar   +1 more source

Immunotherapy of invasive fungal infection in hematopoietic stem cell transplant recipients [PDF]

, 2013
Despite the availability of new antifungal compounds, invasive fungal infection remains a significant cause of morbidity and mortality in children and adults undergoing allogeneic hematopoietic stem cell transplantation (HSCT). Allogeneic HSCT recipients
Klingebiel, Thomas, Lehrnbecher, Thomas, Schmidt, Stanislaw, Tramsen, Lars   +3 more
core   +2 more sources

ZZE-Configuration of chromophore ß-153 in C-phycocyanin from Mastigocladus laminosus [PDF]

, 1987
The photochemistry of C-phycocyanin has been studied after denaturation in the dark. It shows an irreversible reaction which has characteristics of a Ζ,Ζ,Ε- to Z,Z,Z-isomerization of dihydrobilins. Its amplitude depends on the reaction conditions, with
Bode, W., Fischer, R., Huber, R., Rüdiger, W., Scheer, Hugo, Schirmer, T., Schmidt, G., Siebzehnrübl, S.   +7 more
core   +1 more source

Use of Urine Antigen Testing for Blastomyces in an Integrated Health System

Journal of Patient-Centered Research and Reviews, 2018
Purpose: Blastomycosis, an endemic fungal infection, mimics many other diseases. We explored the use of Blastomyces urine antigen (BuAg), reportedly the most sensitive noninvasive test, in clinical practice and compared it to other noninvasive tests ...
Dennis J. Baumgardner
doaj   +1 more source

The Fungal Cell Wall : Structure, Biosynthesis, and Function [PDF]

, 2017
N.G. is funded by the Wellcome Trust via a senior investigator award and a strategic award and by the MRC Centre for Medical Mycology. C.M. acknowledges the support of the Wellcome Trust and the MRC. N.G. and C.M.
Aimanianda, Aimanianda, Al-Fattani, Albrecht, Albuquerque, Alvarez, Arroyo, Babady, Baker, Beauvais, Beauvais, Beauvais, Becker, Bonhomme, Bowen, Brown, Bruno, Bulmer, Butler, Cabib, Cabib, Cabib, Cabib, Casadevall, Casadevall, Cassone, Cassone, Castillo, Chaffin, Cheetham, Cho, Coronado, Couto, Crowe, Cushion, Cutler, Cutler, Da Silva, Dadachova, Dadachova, Dague, Dan, De Las Peñas, Del Poeta, DeMarini, Dennehy, Doering, Domer, Douglas, Douglas, Duro, Eisenhaber, Eisenman, Ene, Erwig, Fairlamb, Fernandes, Firon, Fleet, Fontaine, Frieman, Fu, Gagnon-Arsenault, García, García, Gilbert, Glasgow, Gravelat, Gresnigt, Groot, Groot, Groot, Groot, Hall, Hancock, Henry, Herrero, Hiller, Hilpert, Hohl, Hoyer, Hurtado-Guerrero, Ibrahim, Iorio, Irazoqui, Ito, Johnson, Kanetsuna, Karababa, Kaur, Kim, Klis, Klis, Klutts, Kozubowski, Kozubowski, Lamaris, Langfelder, Larsen, Latge, Latgé, Lee, Lee, Lee, Lenardon, Lenardon, Lesage, Levin, Li, Li, Li, Lipschutz, Lombard, Ma, Ma, MacCallum, Machesky, Macho, Martinez, Marty, Martín-Cuadrado, McFadden, Mentlak, Money, Money, Morelle, Morozov, Mouyna, Mouyna, Moyrand, Munro, Munro, Munro, Müller, Netea, Nett, Nobile, Norice, Nosanchuk, Nosanchuk, Odds, Oliveira-Garcia, Oliveira-Garcia, Ostrosky-Zeichner, Paolo, Paris, Park, Perlin, Piotrowski, Pitarch, Popolo, Pérez, Rachini, Rajendran, Rappleye, Rappleye, Rauceo, Reese, Reese, Reese, Reid, Reinoso-Martín, Rispail, Román, Roncero, Rowbottom, Sandini, Schorr, Schuster, Seidl, Selvaggini, Sendid, Shahinian, Sheppard, Sohn, Sorgo, Spellberg, Staab, Steinbach, Steinbach, Steinberg, Steinberg, Stynen, Sudbery, Sundstrom, Sánchez-Vallet, Thompson, Torosantucci, Treitschke, Tsai, Urban, Valdivia, Vargas-Muñiz, Veerdonk, Virag, Wagener, Walker, Walker, Walker, Walton, Weber, Wessels, Wessels, Wheeler, Wheeler, Wiederhold, Wozniak, Wösten, Xin, xSchuster, Yin, Yoneda, Zaragoza, Zarnowski, Zipfel, Zupancic   +215 more
core   +1 more source

Seed-produced anti-globulin VHH-Fc antibodies retrieve globulin precursors in the insoluble fraction and modulate the Arabidopsis thaliana seed subcellular morphology [PDF]

, 2020
Key message Nanobody-heavy chain (VHH-Fc) antibody formats have the potential to immunomodulate even highly accumulating proteins and provide a valuable tool to experimentally modulate the subcellular distribution of seed storage proteins.
Altmann, Friedrich, Arcalis, Elsa, De Meyer, Thomas, Depicker, Anna, Maleux, Katrien, Melnik, Stanislav, Nolf, Jonah, Stöger, Eva   +7 more
core   +2 more sources

A Novel Insight into the Immunologic Basis of Chronic Granulomatous Invasive Fungal Rhinosinusitis

Allergy & Rhinology, 2016
Background Chronic granulomatous invasive fungal rhinosinusitis (CGIFRS) is a rare disease. The underlying immune responses that drive the development of CGIFRS, as opposed to successful pathogen clearance and controlled inflammation, are not currently ...
William Rae M.R.C.P., Rainer Doffinger F.R.C.Path., Fenella Shelton M.R.C.S., Eleanor Sproson F.R.C.S.(O.R.L.-H.N.S.), Hasnaa Ismail-Koch F.R.C.S.(O.R.L.-H.N.S.), Valerie J. Lund C.B.E., Philip G. Harries F.R.C.S.(O.R.L.-H.N.S.), Efrem Eren F.R.C.Path., Rami J. Salib F.R.C.S.(O.R.L.-H.N.S.)   +8 more
doaj   +1 more source

Lateral Flow Assays for the Diagnosis of Invasive Aspergillosis: Current Status. [PDF]

, 2017
Purpose of reviewDiagnosis during early stages of invasive aspergillosis (IA) and targeted antifungal treatment has the potential to improve survival significantly.
Heldt, Sven, Hoenigl, Martin
core   +1 more source

Immunoproteomic Approach of Extracellular Antigens From Paracoccidioides Species Reveals Exclusive B-Cell Epitopes

Frontiers in Microbiology, 2020
Fungi of the Paracoccidioides genus are the etiological agents of paracoccidioidomycosis (PCM), a systemic mycosis restricted to the countries of Latin America.
A. Moreira, M. A. Oliveira, Lana O’Hara Souza Silva, Moisés Morais Inácio, A. Bailão, J. A. Parente-Rocha, Vanessa Rafaela Milhomem Cruz-Leite, J. Paccez, C. M. de Almeida Soares, S. Weber, C. L. Borges   +10 more
semanticscholar   +1 more source