Results 11 to 20 of about 20,381 (227)

Strongyloides Antigens Alter Cytokines Responses in Toxoplasma gondii-Infected BeWo Trophoblast Cells. [PDF]

Cell Biol Int
ABSTRACT The importance of co‐infections is not yet completely understood, and the impact and direction of their effects vary considerably. This study aimed to evaluate the role of total saline extract (TS) and excretory/secretory (ES) products of Strongyloides venezuelensis filarioid larvae on a maternal‐interface cell model during Toxoplasma gondii ...
Alves FT, Jesus BCG, Diniz MES, Luz LC, Franco PS, Ribeiro VDS, de Carvalho EFG, Barbosa BF, Gonzaga HT.   +8 more
europepmc   +2 more sources

Evaluation of Total Serum IgE Level and Associated Factors in Asthmatic Patients at the University of Gondar Hospital, Northwest Ethiopia: A Comparative Cross-Sectional Study. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Asthma is a chronic respiratory disorder with both genetic and environmental underlying risk factors. Allergic asthma, the most prevalent kind, is mostly ascribed to aberrant T helper type 2 (Th2) inflammation and is brought on by allergens.
Assefa A, Wondmagegn T, Negash M.
europepmc   +2 more sources

Natural variation in immune responses to neonatal mycobacterium bovis bacillus calmette-guerin (BCG) vaccination in a cohort of Gambian infants [PDF]

, 2008
Background There is a need for new vaccines for tuberculosis (TB) that protect against adult pulmonary disease in regions where BCG is not effective.
A Lalvani, A Marchant, AM Cooper, AP Soares, Arnaud Marchant, AS Pym, AV Hill, B Wu, Ben Marais, Chris Finan, D Elias, D O'Donovan, E Jouanguy, G Dai, G Sirugo, GA Colditz, GA Poland, GF Black, GF Black, H Fletcher, H Mahomed, I Malhotra, J Vekemans, JJ Ellner, LB Reichman, LC Rodrigues, M Bonecini-Almeida, M Ota, MA Behr, MA Horwitz, Martin O. C. Ota, Melanie J. Newport, MJ Newport, MJ Newport, MOC Ota, NE Beveridge, PC Hill, PEM Fine, RE Weir, RE Weir, RH Brookes, S Dupuis, S Mallal, SE Dorman, ST Bennett, TB Stop, V Davids   +46 more
core   +6 more sources

How to train your myeloid cells: a way forward for helminth vaccines?

Frontiers in Immunology, 2023
Soil-transmitted helminths affect approximately 1.5 billion people worldwide. However, as no vaccine is currently available for humans, the current strategy for elimination as a public health problem relies on preventive chemotherapy.
Rory Doolan, Rory Doolan, Namitha Putananickal, Namitha Putananickal, Lucienne Tritten, Lucienne Tritten, Lucienne Tritten, Tiffany Bouchery, Tiffany Bouchery   +8 more
doaj   +1 more source

Specialized Dendritic Cells Mediating Peripheral Tolerance to Intestinal Antigens. [PDF]

Immunol Rev
ABSTRACT The immune system is tasked with mounting effective responses to pathogens while preventing inflammation triggered by innocuous antigens, including those derived from self, food, and commensal microbes. This balance is especially critical in the intestine, where dietary and microbial antigens are constantly encountered.
Fu L, Littman DR.
europepmc   +2 more sources

Soil-Transmitted Helminth Vaccines: Are We Getting Closer?

Frontiers in Immunology, 2020
Parasitic helminths infect over one-fourth of the human population resulting in significant morbidity, and in some cases, death in endemic countries.
Ayat Zawawi, Kathryn J. Else
doaj   +1 more source

Helminth species specific expansion and increased TNF-alpha production of non-classical monocytes during active tuberculosis.

PLoS Neglected Tropical Diseases, 2021
Both Mycobacterium tuberculosis infection and helminths may affect innate immune mechanisms such as differential effects on monocytes towards the non-classical and intermediate subsets that favor bacterial persistence.
Gezahegn Bewket, Amare Kiflie, Ebba Abate, Olle Stendahl, Thomas Schön, Robert Blomgran   +5 more
doaj   +1 more source

Recombinant expression systems: the obstacle to helminth vaccines? [PDF]

, 2007
A
Claerebout, Edwin, De Maere, Veerle, Geldhof, Peter, Vercruysse, Jozef   +3 more
core   +2 more sources

Helminth Infections: Recognition and Modulation of the Immune Response by Innate Immune Cells [PDF]

, 2018
The survival of helminths in the host over long periods of time is the result of a process of adaptation or dynamic co-evolution between the host and the parasite. However, infection with helminth parasites causes damage to the host tissues producing the
Ambrosio, Laura Fernanda, Celias, Daiana Pamela, Cervi, Laura Alejandra, Chiapello, Laura Silvina, Motran, Claudia Cristina, Silvane, Leonardo Micael, Theumer, Martín Gustavo, Volpini, Ximena   +7 more
core   +1 more source

Pre-existing helminth infection impairs the efficacy of adjuvanted influenza vaccination in mice.

PLoS ONE, 2022
The world health organization estimates that more than a quarter of the human population is infected with parasitic worms that are called helminths. Many helminths suppress the immune system of their hosts to prolong their survival. This helminth-induced
Wiebke Hartmann, Marie-Luise Brunn, Nadine Stetter, Gülsah Gabriel, Minka Breloer   +4 more
doaj   +1 more source