Results 11 to 20 of about 20,110 (228)
Mixed Signals: T Cells as Architects of IgE Immunity. [PDF]
Immunol RevABSTRACT Food allergen‐specific IgE can cause significant pathology, yet the pathways that generate pathogenic, high‐affinity IgE remain incompletely understood. Increasing evidence suggests that IgE responses arise from the integration of multiple, and sometimes opposing, T cell–derived cues.
Tierney AL +3 more
europepmc +2 more sources
Helminth Antigens Modulate TLR-Initiated Dendritic Cell Activation [PDF]
The Journal of Immunology, 2004 AbstractThere is increasing awareness that helminth infections can ameliorate proinflammatory conditions. In part, this is due to their inherent ability to induce Th2 and, perhaps, regulatory T cell responses. However, recent evidence indicates that helminths also have direct anti-inflammatory effects on innate immune responses.
Colleen M, Kane +7 more
openaire +2 more sources
How to train your myeloid cells: a way forward for helminth vaccines?
Frontiers in Immunology, 2023 Soil-transmitted helminths affect approximately 1.5 billion people worldwide. However, as no vaccine is currently available for humans, the current strategy for elimination as a public health problem relies on preventive chemotherapy.
Rory Doolan +8 more
doaj +1 more source
PLoS Neglected Tropical Diseases, 2021 Both Mycobacterium tuberculosis infection and helminths may affect innate immune mechanisms such as differential effects on monocytes towards the non-classical and intermediate subsets that favor bacterial persistence.
Gezahegn Bewket +5 more
doaj +1 more source
Recombinant expression systems: the obstacle to helminth vaccines? [PDF]
, 2007 A
Claerebout, Edwin +3 more
core +2 more sources
Soil-Transmitted Helminth Vaccines: Are We Getting Closer?
Frontiers in Immunology, 2020 Parasitic helminths infect over one-fourth of the human population resulting in significant morbidity, and in some cases, death in endemic countries.
Ayat Zawawi, Kathryn J. Else
doaj +1 more source
Helminth Infections: Recognition and Modulation of the Immune Response by Innate Immune Cells [PDF]
, 2018 The survival of helminths in the host over long periods of time is the result of a process of adaptation or dynamic co-evolution between the host and the parasite. However, infection with helminth parasites causes damage to the host tissues producing the
Ambrosio, Laura Fernanda +7 more
core +1 more source
Pre-existing helminth infection impairs the efficacy of adjuvanted influenza vaccination in mice.
PLoS ONE, 2022 The world health organization estimates that more than a quarter of the human population is infected with parasitic worms that are called helminths. Many helminths suppress the immune system of their hosts to prolong their survival. This helminth-induced
Wiebke Hartmann +4 more
doaj +1 more source
Promising Technologies in the Field of Helminth Vaccines
Frontiers in Immunology, 2021 Helminths contribute a larger global burden of disease than both malaria and tuberculosis. These eukaryotes have caused human infections since before our earliest recorded history (i.e.: earlier than 1200 B.C. for Schistosoma spp.).
Dilhan J. Perera +5 more
doaj +1 more source
Human ascariasis: diagnostics update [PDF]
, 2015 Soil-transmitted helminths (STHs) infect over one billion people worldwide. Ascariasis may mimic a number of conditions, and individual clinical diagnosis often requires a thorough work-up.
Jourdan, Peter M., Lamberton, Poppy H.L.
core +1 more source