Results 51 to 60 of about 20,381 (227)
Heliyon, 2022 Human toxocariasis is one of the neglected helminthiases and it is caused by the zoonotic roundworm species Toxocara canis and Toxocara cati. Diagnosis of human toxocariasis is based on the combination of clinical, parasitological, and epidemiological ...
Jairo A. Mesa-Arango +5 more
doaj +1 more source
A role for peroxisome proliferator-activated receptors in the immunopathology of schistosomiasis? [PDF]
, 2012 Peroxisome proliferator-activated receptors (PPARs) have been demonstrated to have a role in immune regulation. In general, they are anti-inflammatory and promote Th2 type responses, and they are associated with the alternative activation of macrophages.
Allen, JT +3 more
core +4 more sources
Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium
Advanced Science, EarlyView.This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du +5 more
wiley +1 more source
Advances in Double‐Stranded DNA Targeting Technologies
Exploration, EarlyView.Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen +8 more
wiley +1 more source
Advancing pharmacometrics in Africa—Transition from capacity development toward job creation
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai +10 more
wiley +1 more source
Myeloid-Derived Suppressor Cells: The Expanding World of Helminth Modulation of the Immune System
Frontiers in Immunology, 2022 Infection with helminths or parasitic worms are highly prevalent worldwide especially in developing regions. Helminths cause chronic infections that are associated with suppression of immune responses to unrelated pathogens, vaccines, and by-stander ...
Mary M. Stevenson +3 more
doaj +1 more source
Rheumatology &Autoimmunity, EarlyView.This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley +1 more source
IL-10- and TGFβ-mediated Th9 Responses in a Human Helminth Infection. [PDF]
PLoS Neglected Tropical Diseases, 2016 Th9 cells are a subset of CD4+ T cells that express the protoypical cytokine, IL-9. Th9 cells are known to effect protective immunity in animal models of intestinal helminth infections.
Rajamanickam Anuradha +7 more
doaj +1 more source
Frontiers in Immunology, 2015 The CD3ζ forms part of the T cell receptor (TCR) where it plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways leading to T cell effector functions.
Laura Jane Appleby +8 more
doaj +1 more source
An Enteric Helminth Infection Protects Against an Allergic Response to Dietary Antigen [PDF]
The Journal of Immunology, 2002 AbstractAlthough helminths induce a polarized Th2 response they have been shown, in clinical studies, to confer protection against allergies. To elucidate the basis for this paradox, we have examined the influence of an enteric helminth infection on a model of food allergy.
Mohamed Elfatih H, Bashir +4 more
openaire +2 more sources