Sustainable control of cyathostomin infections in practice
Summary Cyathostomins are the most prevalent helminths in horses and are found in nearly all grazing groups. These parasites have been shown to exhibit widespread anthelmintic resistance and can cause clinical disease, so they are a growing concern.
J. B. Matthews, T. S. Mair
wiley +1 more source
TLRs, Treg and B cells, an interplay of regulation during helminth infection
Commonly described as masters of regulation parasitic helminth infections provide a fascinating insight into the complexity of our immune system. As with many other pathogens helminths have developed complex evasion strategies and the immune response of ...
Laura E Layland, Isis eLudwig-Portugall
doaj +1 more source
Nematode-induced interference with vaccination efficacy targets follicular T helper cell induction and is preserved after termination of infection. [PDF]
One-third of the human population is infected with parasitic worms. To avoid being eliminated, these parasites actively dampen the immune response of their hosts.
Irma Haben +2 more
doaj +1 more source
Plasmodium falciparum and Helminth Coinfections Increase IgE and Parasite-Specific IgG Responses
Coinfection with Plasmodium falciparum and helminths may impact the immune response to these parasites because they induce different immune profiles. We studied the effects of coinfections on the antibody profile in a cohort of 715 Mozambican children ...
Rebeca Santano +27 more
doaj +1 more source
Immune Responses in Human Necatoriasis: Association between Interleukin-5 Responses and Resistance to Reinfection [PDF]
Cytokine and proliferative responses to Necator americanus infection were measured in a treatment-reinfection study of infected subjects from an area of Papua New Guinea where N. americanus is highly endemic.
Brown, A.P. +4 more
core
Distinguishing Features of ILC2s During Type 2 Immune Responses
Group 2 innate lymphoid cells (ILC2s) are tissue‐resident cells regulated by diverse signals often emanating from surrounding nonhematopoietic cells at barrier surfaces. Their effector cytokines determine tissue homeostasis at steady state and during type 2 immunity in allergies or worm infections.
Manuel O. Jakob +2 more
wiley +1 more source
Schistosoma mansoni Infection Can Jeopardize the Duration of Protective Levels of Antibody Responses to Immunizations against Hepatitis B and Tetanus Toxoid. [PDF]
Schistosomiasis is a disease of major public health importance in sub-Saharan Africa. Immunoregulation begins early in schistosome infection and is characterized by hyporesponsiveness to parasite and bystander antigens, suggesting that a schistosome ...
Diana K Riner +9 more
doaj +1 more source
Cellular and humoral immune responses and protection against schistosomes induced by a radiation-attenuated vaccine in chimpanzees [PDF]
The radiation-attenuated Schistosoma mansoni vaccine is highly effective in rodents and primates but has never been tested in humans, primarily for safety reasons.
Abe K. +65 more
core +2 more sources
Reprogramming macrophages to an anti‐inflammatory phenotype by helminth antigens reduces murine atherosclerosis [PDF]
Atherosclerosis is a lipid‐driven inflammatory disease of the vessel wall, characterized by the chronic activation of macrophages. We investigated whether the helminth‐derived antigens [soluble egg antigens (SEAs)] could modulate macrophage inflammatory responses and protect against atherosclerosis in mice.
Wolfs, Ine M. J. +16 more
openaire +5 more sources
Advances in the Role of Adipose Tissue in Promoting Injury Repair and Resist Infection
ABSTRACT Background In recent years, adipose tissue (AT) transplantation has increasingly been noticed by many people in the field of tissue repair and regeneration. Accumulating evidence demonstrates that AT exerts dual functions in promoting tissue repair and conferring anti‐infective properties, with distinct biological effects attributed to its ...
Xi Duan +4 more
wiley +1 more source

