Inhibition of human FcγRIII prevents platelet destruction in a dual-humanized murine model of FNAIT. [PDF]
Tawhidi Z +11 more
europepmc +1 more source
Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu +5 more
wiley +1 more source
Immune-mediated platelet refractoriness: Mechanisms, diagnostics, and therapeutic breakthroughs. [PDF]
Ma L, Wu L, Xie J.
europepmc +1 more source
Inspired by the suction mechanics of octopus suckers, a dual‐layer nanofiber membrane integrates antibacterial protection, strong wet adhesion, and osteogenic support, offering a bioinspired strategy for effective hemostasis and alveolar bone preservation.
Huijing Ma +9 more
wiley +1 more source
Integrated Immunological Engineering Platform for Scalable Production of iPSC-Derived Megakaryocytes. [PDF]
Dettmer R +6 more
europepmc +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source
Extracellular vesicle-mediated immune crosstalk in rheumatoid arthritis synovium: mechanistic insights and translational challenges. [PDF]
Luo F +8 more
europepmc +1 more source
Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang +13 more
wiley +1 more source
Pregnancy-induced Alloimmunization against Platelet Antigens. HLA and Human Platelet Antigens (HPA).
Enomoto, Takayuki +10 more
openaire +2 more sources
Anti-HPA-1a IgG3 subclass antibodies induce strong platelet phagocytosis. [PDF]
Schmidt S +5 more
europepmc +1 more source

