Results 171 to 180 of about 56,164 (204)

Gene frequencies of human platelet antigens in the Macedonian population

Tissue Antigens, 2006
AbstractHuman platelet antigen (HPA) systems consist of more than 12 bi‐allelic antigen polymorphisms. Due to these polymorphisms, platelet‐membrane glycoproteins can be recognized as alloantigens or autoantigens and can cause conditions such as fetomaternal alloimmune thrombocytopenia, post‐transfusion refractoriness to platelets, and post‐transfusion
M, Pavkovic, A, Petlichkovski, A, Strezova, T, Arsov, D, Trajkov, M, Spiroski   +5 more
openaire   +2 more sources

Gene frequencies of human platelet antigens in the Tunisian population

Tissue Antigens, 1999
Abstract:Gene frequencies for the human platelet antigens HPA‐1, ‐3 and ‐5 in the Tunisian population were determined by polymerase chain reaction‐restriction fragment length polymorphism (PCR‐RFLP) on 93 volunteer blood donors (78 were tested for HPA‐1, 90 for HPA‐3 and 93 for HPA‐5).
N, Mojaat, L, Halle, V, Proulle, S, Hmida, L, Ben Hamed, K, Boukef, C, Kaplan   +6 more
openaire   +2 more sources

Human Platelet Antigen Gene Frequencies in the Austrian Population

Haemostasis, 2009
Gene frequencies for the human platelet antigen systems HPA-1, -2, -3, and -5 were determined directly from DNA isolated from cord blood of more than 900 randomly selected Caucasoid newborns in Vienna, Austria. Genotyping was performed by specific amplification of the respective regions coding for platelet glycoproteins GP lb, IIb, IIIa, and la by PCR.
A, Holensteiner, S, Walchshofer, A, Adler, E M, Kittl, W R, Mayr, S, Panzer   +5 more
openaire   +2 more sources

Human platelet antigen‐1a antibodies induce the release of the chemokine RANTES from human platelets

Vox Sanguinis, 2001
Background and ObjectiveBinding of human platelet antigen‐1a (HPA‐1a)‐specific antibodies to target platelets can trigger platelet activation and mediator release. Here we tested the effect of HPA‐1a antibody‐containing sera on platelet release of the chemokine RANTES (regulated on activation, normal, T‐cell expressed, and presumably secreted) in vitro.
M, Dettke, M, Dreer, P, Höcker, S, Panzer   +3 more
openaire   +2 more sources

Genotyping of Human Platelet Antigens by BeadChip Microarray Technology

2015
Human platelet antigen (HPA) typing plays a critical role in the diagnosis of fetal/neonatal alloimmune thrombocytopenia, and the prevention of posttransfusion purpura and refractoriness to platelet transfusions. The recent development of high-throughput genotyping methods, allowing simultaneous genotyping of as many as 17 HPAs, is of utmost interest ...
Gerald, Bertrand, Fabiana, Conti
openaire   +2 more sources

Nomenclature of human platelet antigens

Vox Sanguinis, 2003
P, Metcalfe, N A, Watkins, W H, Ouwehand, C, Kaplan, P, Newman, R, Kekomaki, M, De Haas, R, Aster, Y, Shibata, J, Smith, V, Kiefel, S, Santoso   +11 more
openaire   +2 more sources

Platelet antigens. The role of human platelet alloantigens (HPA) in blood transfusion and transplantation

Transplant Immunology, 2002
In this review, we describe the platelet surface molecules with special focus on the polymorphic glycoproteins giving rise to the human platelet alloantigen (HPA) system. We list the platelet glycoprotein complexes GPIa/IIa, GPIIb/IIIa, GPIb/V/IX and some other molecules, the corresponding genes that encode them and we describe their polymorphisms as ...
openaire   +2 more sources

Noninvasive fetal genotyping of human platelet antigen-1a.

BJOG : an international journal of obstetrics and gynaecology, 2011
We describe a reliable noninvasive fetal human platelet antigen (HPA)-1a genotyping assay on a real-time polymerase chain reaction (PCR) platform using cell-free fetal DNA isolated from maternal blood. Nonspecific amplification of maternal cell-free DNA is overcome by pre-PCR digestion of the cell-free DNA with the Msp1 restriction enzyme.
Scheffer, P.G., Soussan, A.A., Verhagen, O.J.H.M., Page-Christiaens, G.C.M.L., Oepkes, D., Haas, M. de, Schoot, C.E. van der   +6 more
openaire   +3 more sources

Human platelet lysate biotherapy for traumatic brain injury: preclinical assessment

Brain, 2021
Ouada Nébié, Lassina Barro, Ming-Li Chou   +2 more
exaly  

Human Platelet Antigens

2007
Thomas J. Kunicki, Diane J. Nugent
openaire   +1 more source