Results 171 to 180 of about 8,144,327 (289)

Evaluating the diagnostic value of PLR and related hematologic parameters combined with CA‐125 for endometriomas

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Endometriosis is a chronic inflammatory disease, with inflammation relating to pathogenesis and staging. We compared inflammatory indices and clinical characteristics between patients with ovarian endometriomas and those with benign ovarian tumors to evaluate their diagnostic value and identify affordable blood markers for diagnosis ...
Pingping Su, Yanni Huang, Fenhong Kang, Lili Zhang, Lirui Yu, Hongli Liu   +5 more
wiley   +1 more source

Butyrate ameliorates acute‐on‐chronic liver failure by regulating macrophage polarization

iMetaOmics, EarlyView.
Multi‐omics profiling identifies progressive microbiota‐metabolism‐immunity axis dysfunction in acute‐on‐chronic liver failure (ACLF), characterized by gut dysbiosis, reduced butyrate production, intestinal barrier disruption, microbial translocation, and pro‐inflammatory macrophage polarization, thereby exacerbating hepatic inflammation and fibrosis ...
Jing Xiao, Hang You, Zongyi Liu, Yong Sun, Yu Zhang, Li Wei, Ning Ling, Hong Ren, Shiying Li, Peng Hu, Mingli Peng   +10 more
wiley   +1 more source

Immune-mediated platelet refractoriness: Mechanisms, diagnostics, and therapeutic breakthroughs. [PDF]

Transfus Med
Ma L, Wu L, Xie J.
europepmc   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

A Beginner's Guide to Study the Role of Extracellular Vesicles in Coagulation. [PDF]

J Extracell Biol
Nieuwland R, Bracht JWP, Meijers JCM, Thaler J.   +3 more
europepmc   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Metrnl: A Novel Therapeutic Target in Atherosclerosis

iNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Inflammatory regulatory mechanisms and targeted therapy of antineutrophil cytoplasmic antibodies in atherosclerosis (Review). [PDF]

Int J Mol Med
Cui J, Cui Q, Dou J, Li X, Chang W, Shi L, An L.   +6 more
europepmc   +1 more source

Reframing ATR: from the immunologic/nonimmunologic dichotomy to adaptive, innate, and physicochemical drivers within the allergy-inflammation-coagulation axis. [PDF]

Front Immunol
Sakurai Y.
europepmc   +1 more source

Standardization of the Monocyte Monolayer Assay: Lessons Learned From Laboratory Optimization and Literature Review

Journal of Clinical Laboratory Analysis, EarlyView.
Standardization of monocyte monolayer assay in a developing country. This study highlights the significance of literature review and adopting best techniques for standardization of a new procedure at individual center before implementing into practice. ABSTRACT Objectives Several variables influence the outcome of cellular assays.
Shamee Shastry, Kavya Babu, Deepika Chenna, Ganesh Mohan, Kartik Iyer   +4 more
wiley   +1 more source