From Caffeine to Aspirin: Everyday Molecules as Triggers for Genetically Encoded Proximity Systems
This Perspective article highlights how familiar dietary ingredients and over‐the‐counter (OTC) drugs (such as caffeine and its metabolites, SA, and aspirin) can be repurposed as clinically translatable chemical triggers for genetically encoded proximity systems.
Mingguang Cui +5 more
wiley +1 more source
Associations of Inherited Chromosomally-Integrated Human Herpesvirus 6 With Dementia Incidence, Inflammation, and Other Dementia Risk Factors in the UK Biobank. [PDF]
Qiya Z +5 more
europepmc +1 more source
ABSTRACT Peripheral blood mononuclear cells (PBMCs) are commonly used for immune profiling in clinical research, but their isolation and cryopreservation present logistical challenges, particularly in settings with limited access to research facilities. To address this, we implemented a whole blood fixation protocol to preserve surface protein epitopes
Vaishnavi Parthasarathy +8 more
wiley +1 more source
Post-Transfusion Purpura: A Clinical Case With Alveolar Haemorrhage. [PDF]
Yamakova Y +3 more
europepmc +1 more source
Abstract Aberrant antigen expression on mast cells (MCs) is one of the most accurate diagnostic markers for clonal MC diseases (CMCD). Although the coexistence of normal and pathologic MCs is frequently seen, the disease characteristics associated with it have been minimally investigated.
Abdulrazzaq Alheraky +6 more
wiley +1 more source
New perspectives on fetal and neonatal alloimmune thrombocytopenia for obstetricians. [PDF]
Zhao Y +6 more
europepmc +1 more source
Abstract Aims Immune checkpoint inhibitors (ICI) are the cornerstone of modern oncology; however, side effects such as ICI‐related myocarditis (irM) can be fatal. Recently, Bonaca proposed criteria for irM; however, it is unknown if they correlate well with cardiovascular (CV) ICI‐related adverse events.
Lorenzo Braghieri +12 more
wiley +1 more source
Non-PF4/heparin-binding, platelet-activating antibodies in heparin-induced thrombocytopenia. [PDF]
Zhou L +11 more
europepmc +1 more source
Implantable electrochemical sensors for continuous blood monitoring
Implantable electrochemical sensors enable direct, in situ, and continuous blood monitoring, shifting diagnosis from population‐based averages to dynamic, individualized analysis. This review systematically examines the influence of the unique blood properties on sensor design.
Kuangyi Zou +3 more
wiley +1 more source
Molecular basis of coronary artery disease-malignancy comorbidity: inflammation, immunometabolism, thrombosis, and cardio-oncology translation. [PDF]
Li J, Zhao Y, Bai M.
europepmc +1 more source

