Results 151 to 160 of about 56,164 (204)

Clinical characteristics of thrombocytopenia in tropical diseases and management in resource-limited settings. [PDF]

Res Pract Thromb Haemost
Gurumurthy G, Gurumurthy J, Gurumurthy S, Reynolds L, Swan D, Thachil J.   +5 more
europepmc   +1 more source

Platelet Antigen Polymorphisms in Cirrhosis: Association with Esophageal Varices Development. [PDF]

Int J Gen Med
Abdallah HM, Osheba IS, Salman AA, Gaballa NK, Helmi MO, Ibrahim AR, Atta ASS, Saad MG, Aboagiza SM, Abdel Hafez HS, El Helbawy MGED, GabAllah GMK, Elewa A, Salman MA, Abdelmegeed NA.   +14 more
europepmc   +1 more source

Human platelet antigens frequencies in Maori and Polynesian populations

Transfusion Medicine, 2013
SUMMARYBackgroundAllele frequencies of human platelet antigens (HPA) reflect population history and possibility of platelet‐specific alloimmunization. Here, we report on screening of variants at HPA loci for Polynesian and Maori subjects.ObjectivesOur aims are to evaluate new HPA genotyping methods, compile and analyse new HPA datasets for these ...
Edinur, H., J Dunn, P., Lea, Rodney, hambers, G.   +3 more
openaire   +4 more sources

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Human platelet antigens in disease

Clinica Chimica Acta, 2018
Platelets have various functions and participate in primary hemostasis, inflammation, and immune responses. Human platelet antigens (HPAs) are alloantigens expressed on the platelet membrane. Each HPA represent one of six platelet glycoproteins GPIIb, GPIIIa, GPIa, GPIbα, GPIbβ, and CD109, and six biallelic systems are grouped.
Ying-Hao, Wen, Ding-Ping, Chen
openaire   +2 more sources

Molecular Genetics of Human Platelet Antigens

Infusionstherapie und Transfusionsmedizin / Infusion Therapy and Transfusion Medicine, 2009
The purpose of this article is to review the molecular genetics of human platelet antigens, the application of molecular biological techniques to detect mutations underlying polymorphisms and the importance of these techniques for clinical medicine of immunemediated platelet destruction.
S, Simsek, A E, von dem Borne
openaire   +2 more sources

Status of the MNSs antigens on human platelets

Transfusion, 1987
A sensitive and specific radioimmunoassay was used to determine whether human platelets possess antigens of the MNSs blood group. Mouse monoclonal IgG anti‐M and anti‐N were purified by Staphylococcus protein A chromatography, labeled with 125I, and incubated with platelet pellets from donors of various MN phenotypes. Human IgG anti‐ M, ‐S, and ‐s were
M B, Simpson, R A, Dunstan, W F, Rosse, A C, Munro, R, Fraser, M E, Nichols   +5 more
openaire   +2 more sources

Antithrombin III Antigen in Human Platelets

Thrombosis and Haemostasis, 1985
SummaryImmunoreactive AT III was found in human platelets. AT III antigen was quantified in platelets taken from each of 17 healthy donors by a specific competitive enzyme immunoassay using purified AT III and AT III antibodies. AT III antigen levels in extracts of washed platelets disrupted by freezing and thawing ranged from 32 to 140 ng per 109 ...
M L, Alhenc-Gelas, M, Aiach, A, Gorenflot, J P, Andreaux   +3 more
openaire   +2 more sources

Human platelet antigen genotyping of platelet donors in southern Brazil

International Journal of Immunogenetics, 2015
SummaryHuman platelet antigens (HPA) are immunogenic structures that result from single nucleotide polymorphisms (SNPs) leading to single amino acid substitutions. This study sought to determine the allele and genotype frequencies of HPA‐1, HPA‐2, HPA‐3, HPA‐4, HPA‐5 and HPA‐15 in platelet donors from the state of Rio Grande do Sul (RS), Brazil, and ...
J. Merzoni, I. S. Fagundes, L. W. Lunardi, J. D.‐R. Lindenau, B. C. Gil, M. Jobim, V. G. Dias, L. Merzoni, L. Sekine, T. G. H. Onsten, L. F. Jobim   +10 more
openaire   +2 more sources