Results 61 to 70 of about 8,144,327 (289)

Engineering antibodies against complex platelet antigens using phage display technology [PDF]

, 2007
Platelets are small anucleate cell fragments found in blood whose physiological role is important in maintaining haemostasis. In vivo, platelet surface glycoproteins mediate the mechanistic roles of platelets, and polymorphic changes to these ...
De Leon, Ellen Jane
core   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Diagnosis of Neonatal Alloimmune Thrombocytopenia: Determination of the Specificity of Antiplatelet Alloantibodies in the Maternal Blood Plasma Using a Molecular and Genetic Method

Инновационная медицина Кубани, 2023
Background: Thrombocytopenia occurs in 1-5 % of newborns (platelet count < 150 × 109/L). Low platelet count of 50 × 109/L leads to the hemorrhagic syndrome, with one of its causes being neonatal alloimmune thrombocytopenia resulting from ...
N. V. Mineeva, S. V. Gavrovskaya, E. A. Sysoeva, S. V. Sidorkevich   +3 more
doaj   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

Advanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani, Abu ul Hassan S. Rana, S. Sudheer Khan   +2 more
wiley   +1 more source

PLT antigen discrepancy pattern among couples with recurrent abortion

Frontiers in Medicine
BackgroundRecurrent abortion refers to a condition of two or more consecutive pregnancies without known etiology affected by miscarriage before the completion of the 20th week of gestational age.
Ghazal Ahmadzadeh Shad, Ali Ghasemi, Maryam Zadsar, Mojgan Shaeigan, Shahram Samiee, Ahad Zare   +5 more
doaj   +1 more source

Applicability of an instrument to identify human leukocyte antigen-compatible donors for platelet transfusions

Hematology, Transfusion and Cell Therapy, 2018
Background: The selection of compatible human leukocyte antigen platelets has been associated with improved platelet increments. Therefore, an effective strategy would be the selection of donors who are genetically compatible according to the human ...
Millena Gomes Ferreira, Fernanda Bernadelli De Vito, Aline Aparecida Ferreira, Carolina Bonet Bub, Fernando Antônio Vinhal dos Santos, Adilson Botelho Filho, Sheila Soares Silva, Helio Moraes-Souza   +7 more
doaj   +1 more source

Scalable Production of Equine Platelet Lysate for Multipotent Mesenchymal Stromal Cell Culture

Frontiers in Bioengineering and Biotechnology, 2021
Translation of multipotent mesenchymal stromal cell (MSC)-based therapies is advancing in human and veterinary medicine. One critical issue is the in vitro culture of MSC before clinical use.
A. Hagen, H. Lehmann, S. Aurich, N. Bauer, M. Melzer, J. Moellerberndt, V. Patané, C. L. Schnabel, J. Burk   +8 more
doaj   +1 more source

Platelet-independent methods for detecting antibodies to human platelet antigens.

Blood transfusion = Trasfusione del sangue, 2015
Dear Sir, I read with great interest the review paper entitled “Advances in alloimmune thrombocytopenia: perspectives on current concepts of human platelet antigens, antibody detection strategies, and genotyping” by Hayashi T et al., which was published recently in Blood Transfusion1.
openaire   +2 more sources

Human platelet‐specific antigens frequencies in the Argentinean population [PDF]

Transfusion Medicine, 2008
summary The frequencies of several human platelet antigens (HPAs) vary between different populations and are a major determinant for the prevalence of HPA alloimmunization and its clinical associated entities. The aim of this study was to characterize the allele frequencies of seven HPA systems in two different ethnic groups from the Argentinean city ...
C D, De La Vega Elena, N, Nogués, A, Fernández Montoya, S, Chialina, P D, Blanzaco, E, Theiller, M A, Raillon, N, Arancegui, E, Solis, S, Oyonarte, V, Crespo Ferrer, A, Campos Muñoz, E, Muñiz-Díaz   +12 more
openaire   +2 more sources