Results 41 to 50 of about 56,164 (204)

Transfusion medicine and molecular genetic methods

International Journal of Preventive Medicine, 2018
Transfusion procedures are always complicated by potential genetic mismatching between donor and recipient. Compatibility is determined by several major antigens, such as the ABO and Rhesus blood groups. Matching for other blood groups (Kell, Kidd, Duffy,
Rozieyati Mohamed Saleh, Zulkafli Zefarina, Nor Fazila Che Mat, Geoffrey Keith Chambers, Hisham Atan Edinur   +4 more
doaj   +1 more source

Platelet Toll-Like-Receptor-2 and -4 Mediate Different Immune-Related Responses to Bacterial Ligands

TH Open, 2022
Background Like immune cells, platelets express toll-like receptors (TLRs) on their surface membrane. TLR2 and TLR4 are able to recognize bacterial antigens and have the potential to influence hemostatic functions and classical intracellular signaling ...
Marius Niklaus, Philipp Klingler, Katja Weber, Angela Koessler, Sabine Kuhn, Markus Boeck, Anna Kobsar, Juergen Koessler   +7 more
doaj   +1 more source

Platelets Aggregate With Neutrophils and Promote Skin Pathology in Psoriasis

Frontiers in Immunology, 2019
Psoriasis is a frequent systemic inflammatory autoimmune disease characterized primarily by skin lesions with massive infiltration of leukocytes, but frequently also presents with cardiovascular comorbidities.
Franziska Herster, Zsofia Bittner, Marius Cosmin Codrea, Nathan K. Archer, Martin Heister, Markus W. Löffler, Markus W. Löffler, Markus W. Löffler, Simon Heumos, Joanna Wegner, Ramona Businger, Michael Schindler, David Stegner, Knut Schäkel, Stephan Grabbe, Kamran Ghoreschi, Kamran Ghoreschi, Lloyd S. Miller, Alexander N. R. Weber   +18 more
doaj   +1 more source

Allele frequencies of Human Platelet Antigen 1 and Human Platelet Antigen 5 in the Maltese

, 2021
Background: The human platelet antigen systems consist of antigenic polymorphisms that arise from single base pair substitutions leading to amino acid changes in platelet glycoproteins. These polymorphisms cause a variety of clinically significant conditions where platelet typing is essential for accurate diagnosis and subsequent treatment.
Falzon Lia, Martina, Samut Tagliaferro, Sarah, Farrugia, Rosienne   +2 more
openaire   +1 more source

The Carcinoembryonic Antigen Gene Family [PDF]

, 1988
The molecular cloning of carcinoembryonic antigen (CEA) and several cross-reacting antigens reveals a basic domain structure for the whole family, which shows structural similarities to the immunoglobulin superfamily.
Zimmermann, Wolfgang, Thompson, John A.
core  

Allele and haplotype frequencies of human platelet and leukocyte antigens in platelet donors

, 2019
Objective To described the allele and haplotype frequencies of human leukocyte antigen genes at the -A, -B loci and human platelet antigen genes for human platelet antigen systems 1 to 9, 11 and 15 in blood.
Maria Giselda Aravechia (6327761), Eduardo Peres Bastos (6327758), Thiago Henrique Costa (6327752), Leandro Dinalli Santos (6327755), Carolina Bonet Bub (6327749), Valeria de Freitas Dutra (6327746), José Mauro Kutner (6327764)   +6 more
core   +1 more source

Diagnosis of Neonatal Alloimmune Thrombocytopenia: Determination of the Specificity of Antiplatelet Alloantibodies in the Maternal Blood Plasma Using a Molecular and Genetic Method

Инновационная медицина Кубани, 2023
Background: Thrombocytopenia occurs in 1-5 % of newborns (platelet count < 150 × 109/L). Low platelet count of 50 × 109/L leads to the hemorrhagic syndrome, with one of its causes being neonatal alloimmune thrombocytopenia resulting from ...
N. V. Mineeva, S. V. Gavrovskaya, E. A. Sysoeva, S. V. Sidorkevich   +3 more
doaj   +1 more source

Studies of human immune responses to various antigenic proteins of Chlamydia trachomatis [PDF]

Chlamydiae are gram-negative bacteria which cause diverse diseases of humans and animals. Chlamydia trachomatis, the focus of this work, causes the blinding eye disease trachoma, and reproductive tract infections.
Felton, John Mark
core   +1 more source

Applicability of an instrument to identify human leukocyte antigen-compatible donors for platelet transfusions

Hematology, Transfusion and Cell Therapy, 2018
Background: The selection of compatible human leukocyte antigen platelets has been associated with improved platelet increments. Therefore, an effective strategy would be the selection of donors who are genetically compatible according to the human ...
Millena Gomes Ferreira, Fernanda Bernadelli De Vito, Aline Aparecida Ferreira, Carolina Bonet Bub, Fernando Antônio Vinhal dos Santos, Adilson Botelho Filho, Sheila Soares Silva, Helio Moraes-Souza   +7 more
doaj   +1 more source

Scalable Production of Equine Platelet Lysate for Multipotent Mesenchymal Stromal Cell Culture

Frontiers in Bioengineering and Biotechnology, 2021
Translation of multipotent mesenchymal stromal cell (MSC)-based therapies is advancing in human and veterinary medicine. One critical issue is the in vitro culture of MSC before clinical use.
A. Hagen, H. Lehmann, S. Aurich, N. Bauer, M. Melzer, J. Moellerberndt, V. Patané, C. L. Schnabel, J. Burk   +8 more
doaj   +1 more source