Results 21 to 30 of about 56,164 (204)

Human platelet antigens – 2013 [PDF]

Vox Sanguinis, 2013
To date, 33 human platelet alloantigens (HPAs) have been identified on six functionally important platelet glycoprotein (GP) complexes and have been implicated in alloimmune platelet disorders including foetal and neonatal alloimmune thrombocytopenia (FNAIT), posttransfusion purpura (PTP) and multitransfusion platelet refractoriness (MPR). The greatest
B R, Curtis, J G, McFarland
openaire   +2 more sources

Genotyping of Human Platelet Antigen-1 to -5 and -15 by Polymerase Chain Reaction with Sequence-specific Primers (PCR-SSP) and Real-time PCR in Azeri Blood Donors

Iranian Journal of Allergy, Asthma and Immunology, 2021
Human platelet antigens (HPAs) are glycoproteins on the platelet surface that a single nucleotide mutation in the coding region gene could lead to the variation of different HPA polymorphisms. These antigens have shown variation among different races and
Seyed Ghader Azizi, Shahram Samiee, Mojgan Shaiegan, Maryam Zadsar   +3 more
doaj   +1 more source

Association of the human platelet antigens polymorphisms with platelet count in patients with COVID-19

Frontiers in Medicine, 2023
Polymorphism in human platelet antigen (HPA)-1 and HPA-3 (GPIIb/IIIa), HPA-2 (GPIb/IX), HPA-4 (GPIIIa), HPA-5 (GPIa/IIa), & HPA-15 (CD109) was investigated in 86 COVID-19-infected patients with thrombocytopenia (Group A) and 136 COVID-19-infected ...
Kazem Ghaffari, Kazem Ghaffari, Mahsa Ashrafi Rad, Amin Moradi Hasan-Abad, Mersedeh Khosravi, Arefeh Benvidi, Mahsa Iraji, Heidar Ali Heidari Khargh, Ali Ghasemi, Ali Ghasemi   +9 more
doaj   +1 more source

The origin of ABH antigens on human platelets [PDF]

Blood, 1985
Abstract ABH antigens are present on platelets from individuals of the corresponding red cell phenotype, but the extent to which these antigens are intrinsic or adsorbed remains undefined. To evaluate platelets for intrinsic H substance, an IgM mouse monoclonal antibody against type 2H chain (the intrinsic H structure found on ...
R A, Dunstan, M B, Simpson, R W, Knowles, W F, Rosse   +3 more
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Simultaneous genotyping for human platelet antigen systems and HLA-A and HLA-B loci by targeted next-generation sequencing

Frontiers in Immunology, 2022
In order to treat the alloimmunization platelet transfusion refractoriness (PTR), human leukocyte antigen (HLA)-type and/or human platelet antigen (HPA)-type matched platelets between donors and patients are usually used.
Jielin Wang, Jielin Wang, Xuan You, Xuan You, Yanmin He, Yanmin He, Xiaozhen Hong, Xiaozhen Hong, Ji He, Ji He, Sudan Tao, Sudan Tao, Faming Zhu, Faming Zhu   +13 more
doaj   +1 more source

Unappreciated HLA Antibodies in Adult Immune Thrombocytopenic Purpura

Journal of the Formosan Medical Association, 2007
Immune thrombocytopenic purpura (ITP) is an autoimmune disease. Platelet refractoriness is frequently seen in patients with ITP. Platelets express platelet-specific antigens and human leukocyte antigens (HLA).
Jeong-Shi Lin, Jau-Yi Lyou, Ying-Ju Chen, Pei-Shan Chen, Hsueng-Mei Liu, Chao-Hung Ho, Tsung-Chi Hao, Cheng-Hwai Tzeng   +7 more
doaj   +1 more source

Human platelet antigen-3 polymorphism as a risk factor for rheumatological manifestations in hepatitis C

Revista da Sociedade Brasileira de Medicina Tropical, 2020
INTRODUCTION: Hepatitis C virus (HCV) infection is involved in the pathogenesis of autoimmune and rheumatic disorders. Although the human platelet antigens (HPA) polymorphism are associated with HCV persistence, they have not been investigated in ...
Natália Bronzatto Medolago, Adriana Camargo Ferrasi, Oswaldo Melo da Rocha, Maria Inês de Moura Campos Pardini, Rejane Maria Tommasini Grotto, Aline Faria Galvani, Giovanni Faria Silva   +6 more
doaj   +1 more source

Frequency of human platelet antigens −1 to −5 and −15 in Turkmen blood donors

Advanced Biomedical Research, 2023
Background: Due to the presence of platelet antigen polymorphisms, human platelet membrane glycoproteins can be identified as an alloantigen or autoantigen.
Maedeh Nozarimirarkolaei, Maryam Dadashi, Ali Ghasemi, Shahram Samiee, Mojgan Shaeigan, Maryam Zadsar   +5 more
doaj   +1 more source

A case report of neonatal alloimmune thrombocytopenia: The utility of platelet crossmatch studies in the diagnosis and management

Global Journal of Transfusion Medicine, 2019
Alloimmune thrombocytopenia is the most common cause of severe thrombocytopenia and intracranial bleed in the perinatal period, resulting from placental transfer of maternal platelet antibodies directed against the paternal-derived fetal platelet ...
H A Venkatesh, Abhishek Paul, Ambuja Kantharaj, Shivaram Chandrashekar   +3 more
doaj   +1 more source

Immunocytochemical Studies on Platelets. The Demonstration of a Common Antigen in Human Platelets and Megakaryocytes [PDF]

Blood, 1960
Abstract By means of the fluorescent antibody technic of Coons and Kaplan it was possible to demonstrate a common antigenic structure in human platelets and megakaryocytes, both in nonthrombocytopenic cases and in cases with idiopathic thrombocytopenic purpura.
J J, VAZQUEZ, J H, LEWIS
openaire   +2 more sources