Results 31 to 40 of about 56,164 (204)

Platelet antibody detection assays: a single-laboratory comparison of MAIPA, PIFT, and microsphere-based multiplex assays Pak-Lx

Hematology, Transfusion and Cell Therapy
Background and Objectives: The identification of platelet antibodies is essential for diagnosing and managing conditions such as fetal and neonatal alloimmune thrombocytopenic purpura, post-transfusion purpura, and immune platelet refractoriness ...
Thiago Henrique Costa, Carolina Bonet-Bub, José Mauro Kutner   +2 more
doaj   +1 more source

Carcinoembryonic Antigen Gene Family [PDF]

, 1991
The carcinoembryonic antigen (CEA) gene family belongs to the immunoglobulin supergene family and can be divided into two main subgroups based on sequence comparisons.
Zimmermann, Wolfgang, Grunert, Fritz, Thompson, John A.   +2 more
core   +1 more source

A case report of neonatal alloimmune thrombocytopenic purpura: the importance of correct diagnosis for future pregnancies

São Paulo Medical Journal
CONTEXT: Neonatal alloimmune thrombocytopenic purpura (NAITP) is a neonatal disorder characterized by maternal alloimmunization against fetal platelet antigens inherited from the father.
Rita Fontão-Wendel, Silvano Wendel, Vicente Odone, Jorge David Carneiro, Leandra Silva, Eduardo Isfer   +5 more
doaj   +1 more source

Gene frequencies of the five major human platelet antigens in African American white and Korean population

, 1995
BACKGROUND: The study of the immunogenetics of the human platelet antigens is important to the improvement of diagnosis and genetic counseling and to the development of screening programs for women at risk of having babies with neonatal alloimmune ...
김현옥
core   +1 more source

Phagocytosis of platelets opsonized with differently glycosylated anti-HLA hIgG1 by monocyte-derived macrophages

Platelets, 2023
Immune-mediated platelet refractoriness (PR) remains a significant problem in the setting of platelet transfusion and is predominantly caused by the presence of alloantibodies directed against class I human leukocyte antigens (HLA). Opsonization of donor
Thijs L. J. van Osch, Juulke Steuten, Jan Nouta, Carolien A. M. Koeleman, Arthur E. H. Bentlage, Sebastiaan Heidt, Arend Mulder, Jan Voorberg, S. Marieke van Ham, Manfred Wuhrer, Anja ten Brinke, Gestur Vidarsson   +11 more
doaj   +1 more source

Microfluidic approach to genotyping human platelet antigens

IET Nanobiotechnology, 2012
Centralised laboratories routinely determine blood types by serological and molecular methods. Current practices have limitations in terms of cost, time and accessibility. Miniaturised microfluidic platforms offer an alternative to conventional genotyping methods, since they consume fewer reagents, provide faster analysis and allow for complete ...
C, Lim, D P, Manage, A, Atrazhev, G, Denomme, C J, Backhouse, J P, Acker   +5 more
openaire   +2 more sources

Anti-HPA-1b Mediated Posttransfusion Purpura: A Case Report

Case Reports in Medicine, 2013
Posttransfusion purpura (PTP) is an uncommon, but potentially fatal, transfusion reaction characterized by profound thrombocytopenia and bleeding. PTP is caused by alloimmunization to human platelet specific antigens following blood component transfusion.
O. P. Arewa, S. Nahirniak, G. Clarke
doaj   +1 more source

Human platelet antigen allelic diversity in Peninsular Malaysia [PDF]

Immunohematology, 2016
Abstract Human platelet antigens (HPAs) are polymorphic and immunogenic glycoproteins encoded by biallelic genes on human chromosome 17 (HPA-1 to -4 and HPA-6 to -11), chromosome 5 (HPA-5), and chromosome 6 (HPA-15) and expressed on the surface of platelets. In the present study, we typed seven HPA loci (HPA-1 to -
Wan Ubaidillah W, Syafawati, Zulkafli, Zefarina, Zafarina, Zafarina, Mohd Nazri, Hassan, Mohd Nor, Norazmi, Sundararajulu, Panneerchelvam, Geoffrey K, Chambers, Hisham Atan, Edinur   +7 more
openaire   +2 more sources

Platelet adhesion in atherogenesis [PDF]

, 2010
A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Master of PhilosophyPlatelets are known to play a key role in acute coronary events, such as myocardial infarction, associated with advanced
Watkins, Jennifer
core  

Engineering antibodies against complex platelet antigens using phage display technology

, 2007
Platelets are small anucleate cell fragments found in blood whose physiological role is important in maintaining haemostasis. In vivo, platelet surface glycoproteins mediate the mechanistic roles of platelets, and polymorphic changes to these ...
De Leon, Ellen Jane
core   +1 more source