Results 11 to 20 of about 8,144,327 (289)

Molecular typing of human platelet antigens in immune thrombocytopenia patients in northern Brazil

Revista Brasileira de Hematologia e Hemoterapia
Background: Immune thrombocytopenia is an immune disease characterized by thrombocytopenia and bleeding due to platelet antibodies against platelet membrane glycoproteins. Human platelet antigens are derived from polymorphisms of these glycoproteins. The
Julia Cavalcante do Carmo, Prissyla de Souza Klippel, Sabrine da Costa Cordeiro, Ângela Maria dos Santos Fernandes, Raquel Medeiros Pinto, Simone Schneider Weber, Cleiton Fantin   +6 more
doaj   +2 more sources

Allele and haplotype frequencies of human platelet and leukocyte antigens in platelet donors [PDF]

Einstein (São Paulo), 2019
Objective To described the allele and haplotype frequencies of human leukocyte antigen genes at the -A, -B loci and human platelet antigen genes for human platelet antigen systems 1 to 9, 11 and 15 in blood.
Valeria de Freitas Dutra, Carolina Bonet Bub, Thiago Henrique Costa, Leandro Dinalli Santos, Eduardo Peres Bastos, Maria Giselda Aravechia, José Mauro Kutner   +6 more
doaj   +4 more sources

Human platelet antigens and primary immune thrombocytopenia

Revista Brasileira de Hematologia e Hemoterapia, 2017
Vagner Castro
doaj   +3 more sources

Pyelolithotomy in a patient with Glanzmann thrombasthenia and antiglycoprotein IIb/IIIa antibodies: the shortest possible duration of treatment with recombinant activated factor VII and platelet transfusions

The Turkish Journal of Pediatrics, 2003
Transfusion of platelet concentrates remains the first-line therapy for Glanzmann thrombasthenia in case of bleeding or preparation for surgery. However, development of antibodies to platelet glycoprotein (Gp) IIb/IIIa complex or human leukocyte ...
Omer Devecioğlu, Ayşegül Unüvar, Sema Anak, Ilmay Bilge, Haluk Ander, Orhan Ziylan   +5 more
doaj   +1 more source

Development of quantitative monoclonal antibody-specific immobilization of platelet antigens assay for antibodies against human platelet antigen-1a, 3a, and 5b

Platelets, 2018
Human platelet antigens (HPAs) are platelet-specific alloantigens that cause alloimmunization. Alloantibodies induced via pregnancy and transfusion may result in various clinical syndromes.
R.S. Li, B. Ling, P. Lu
doaj   +2 more sources

Human platelet antigens frequencies in Maori and Polynesian populations

Transfusion Medicine, 2013
SUMMARYBackgroundAllele frequencies of human platelet antigens (HPA) reflect population history and possibility of platelet‐specific alloimmunization. Here, we report on screening of variants at HPA loci for Polynesian and Maori subjects.ObjectivesOur aims are to evaluate new HPA genotyping methods, compile and analyse new HPA datasets for these ...
Edinur, H., J Dunn, P., Lea, Rodney, hambers, G.   +3 more
openaire   +4 more sources

Human platelet antigens – 2013 [PDF]

Vox Sanguinis, 2013
To date, 33 human platelet alloantigens (HPAs) have been identified on six functionally important platelet glycoprotein (GP) complexes and have been implicated in alloimmune platelet disorders including foetal and neonatal alloimmune thrombocytopenia (FNAIT), posttransfusion purpura (PTP) and multitransfusion platelet refractoriness (MPR). The greatest
B R, Curtis, J G, McFarland
openaire   +2 more sources

The origin of ABH antigens on human platelets [PDF]

Blood, 1985
Abstract ABH antigens are present on platelets from individuals of the corresponding red cell phenotype, but the extent to which these antigens are intrinsic or adsorbed remains undefined. To evaluate platelets for intrinsic H substance, an IgM mouse monoclonal antibody against type 2H chain (the intrinsic H structure found on ...
R A, Dunstan, M B, Simpson, R W, Knowles, W F, Rosse   +3 more
openaire   +3 more sources

Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]

, 2002
Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Day, S., Chaudhry, M.A., Muriithi, E.W., Belcher, P.R.   +3 more
core   +4 more sources

Human Platelet Antigen Genotyping and Expression of CD109 (Human Platelet Antigen 15) mRNA in Various Human Cell Types [PDF]

BioMed Research International, 2013
CD109 gene encodes a glycosylphosphatidylinositol-linked glycoprotein found in a subset of platelets and endothelial cell, and human platelet antigen (HPA) 15 is found on CD109. We evaluated the HPA genotype and/or the CD109 mRNA expression on two peripheral blood stem cells (PBSC), two peripheral bloods (PB), 12 granulocyte products, natural killer ...
Hwang, Sang Mee, Kim, Mi Jung, Chang, Ho Eun, Hong, Yun Ji, Kim, Taek Soo, Song, Eun Young, Park, Kyoung Un, Song, Junghan, Han, Kyou-Sup   +8 more
openaire   +2 more sources