Results 11 to 20 of about 56,164 (204)

Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets [PDF]

Haematologica, 2022
Approximately 20% of patients receiving multiple platelet transfusions develop platelet alloantibodies, which can be directed against human leukocyte antigens (HLA) and, to a lesser extent, against human platelet antigens (HPA).
Thijs L.J. van Osch, Janita J. Oosterhoff, Arthur E. H. Bentlage, Jan Nouta, Carolien A. M. Koeleman, Dionne M. Geerdes, Juk Yee Mok, Sebastiaan Heidt, Arend Mulder, Wim J. E. van Esch, Rick Kapur, Leendert Porcelijn, C. Ellen van der Schoot, Masja de Haas, Manfred Wuhrer, Jan Voorberg, Gestur Vidarsson   +16 more
doaj   +6 more sources

Prevalence and Specificity of Anti-HPA and Anti-HLA Antibodies in Patients with Suspected Immune-Mediated Platelet Disorders: A Single-Center Study from Serbia [PDF]

Medicina
Background and Objectives: Alloantibodies directed against human platelet antigens and human leukocyte antigens are implicated in several immune-mediated platelet disorders, including platelet transfusion refractoriness, post-transfusion purpura and ...
Svetlana Vojvodić, Jasmina Grujić
doaj   +2 more sources

Allele and haplotype frequencies of human platelet and leukocyte antigens in platelet donors [PDF]

Einstein (São Paulo), 2019
Objective To described the allele and haplotype frequencies of human leukocyte antigen genes at the -A, -B loci and human platelet antigen genes for human platelet antigen systems 1 to 9, 11 and 15 in blood.
Valeria de Freitas Dutra, Carolina Bonet Bub, Thiago Henrique Costa, Leandro Dinalli Santos, Eduardo Peres Bastos, Maria Giselda Aravechia, José Mauro Kutner   +6 more
doaj   +4 more sources

Localization of platelet antigens in human kidney disease

Kidney International, 1980
The localization of a platelet antigen or antigens kidneys from 106 patients with renal disease was evaluated with immunofluorescent microscopy by using a rabbit antibody to human platelets. The antiplatelet IgG fixed to the surface membrane of platelets did not react with erythrocytes, leukocytes, plasma, normal kidney, or a variety of normal tissue ...
Miller, Kenneth, Dresner, Ian G., Michael, Alfred F.   +2 more
openaire   +3 more sources

Molecular typing of human platelet antigens in immune thrombocytopenia patients in northern Brazil

Revista Brasileira de Hematologia e Hemoterapia
Background: Immune thrombocytopenia is an immune disease characterized by thrombocytopenia and bleeding due to platelet antibodies against platelet membrane glycoproteins. Human platelet antigens are derived from polymorphisms of these glycoproteins. The
Julia Cavalcante do Carmo, Prissyla de Souza Klippel, Sabrine da Costa Cordeiro, Ângela Maria dos Santos Fernandes, Raquel Medeiros Pinto, Simone Schneider Weber, Cleiton Fantin   +6 more
doaj   +2 more sources

Demand for human leukocyte antigen or human platelet antigen-selected platelets: An observational study at Canadian Blood Services. [PDF]

Transfusion
Abstract Background Platelet transfusion refractoriness (PTR) is a clinically important condition. The Human Leukocyte Antigen and Human Platelet Antigen (HLA/HPA) Platelet Program at Canadian Blood Services (CBS) provides platelet products to support such patients.
Rickards N, Hoang PD, Mack J, Seftel M, Blake JT, Gupta A.   +5 more
europepmc   +3 more sources

The absence of the human platelet antigen polymorphism effect on fibrosis progression in human immunodeficiency virus-1/hepatitis C virus coinfected patients [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2015
INTRODUCTION:Hepatic fibrosis progression in patients with chronic hepatitis C virus infections has been associated with viral and host factors, including genetic polymorphisms.
Natália Picelli, Aline Aki Tanikawa, Rejane Maria Tommasini Grotto, Giovanni Faria Silva, Alexandre Naime Barbosa, Adriana Camargo Ferrasi, Liciana Vaz de Arruda Silveira, Maria Inês de Moura Campos Pardini   +7 more
doaj   +2 more sources

Development of quantitative monoclonal antibody-specific immobilization of platelet antigens assay for antibodies against human platelet antigen-1a, 3a, and 5b

Platelets, 2018
Human platelet antigens (HPAs) are platelet-specific alloantigens that cause alloimmunization. Alloantibodies induced via pregnancy and transfusion may result in various clinical syndromes.
R.S. Li, B. Ling, P. Lu
doaj   +2 more sources

Human platelet antigens and primary immune thrombocytopenia

Revista Brasileira de Hematologia e Hemoterapia, 2017
Vagner Castro
doaj   +3 more sources

Comments on: frequency of human platelet antigens in oncohematological patients with thrombocytopenia and the probability of incompatibility to platelet transfusions

Revista Brasileira de Hematologia e Hemoterapia, 2012
[No abstract available]343180181Castro, V., Origa, A.F., Annichino-Bizzacchi, J.M., Soares, M., Menezes, R.C., Gonçalves, M.S., Frequencies of platelet-specific alloantigen systems 1-5 in three distinct ethnic groups in Brazil (1999) Eur J Immunogenet ...
Erich Vinicius de Paula
doaj   +2 more sources