Results 91 to 100 of about 30,296 (204)

ILC2 Diversity, Location, and Function in Pulmonary Disease

Immunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT Type‐2 inflammation is driven by the production of canonical type‐2 cytokines IL‐4, IL‐5, and IL‐13. Type‐2 cytokines promote mucus production, innate immune cell recruitment, and smooth muscle contractility in mucosal tissues. These hallmarks of type‐2 inflammation are important contributors to the weep‐and‐sweep responses observed in the ...
Mukesh Verma, Uryan I. Can, R. Lee Reinhardt   +2 more
wiley   +1 more source

Characterization of novel microneme adhesive repeats (MAR) in Eimeria tenella [PDF]

, 2017
In this study, we evaluated the binding capacity of Type I MAR domains from novel E. tenella MCPs. Variants of the previously described HxT motif were analysed showing that HxT and VxT variants bind, whereas HxS and YxE variants did not. One of these MCP
Marugan-Hernandez, V, Fiddy, R, Nurse-Francis, J, Smith, O, Pritchard, L, Tomley, F M   +5 more
core   +1 more source

Characterization of T cell clones from chagasic patients: predominance of CD8 surface phenotype in clones from patients with pathology

Memorias do Instituto Oswaldo Cruz, 1995
Human Chagas' disease, caused by the protozoan Trypanosoma cruzi, is associated with pathological processes whose mechanisms are not known. To address this question, T cell lines were developed from chronic chagasic patients peripheral blood mononuclear ...
Washington R. Cuna, Celeste Rodriguez Cuna   +1 more
doaj   +1 more source

Cost‐Effective Nanosensor Solutions for Ultra‐Sensitive Detection of Metronidazole

Analytical Science Advances, Volume 6, Issue 1, June 2025.
ABSTRACT Metronidazole (MNZ) is a widely used imidazole antibiotic effective against bacterial and protozoal infections, including giardiasis, trichomoniasis, bacterial vaginosis, and antibiotic‐associated colitis. However, prolonged and excessive use of MNZ can lead to serious side effects, such as peripheral neuropathies, toxicity, and optic ...
Ahmad Mobed, Mohammad Darvishi, Vahid Alivirdiloo, Sara Ebrahimi, Mobasher Hajiabbasi, Farhood Ghazi, Hamidreza Hassanzadeh Khanmiri   +6 more
wiley   +1 more source

Gametocytes: insights gained during a decade of molecular monitoring [PDF]

, 2008
In vertebrate hosts, malaria parasites produce specialized male and female sexual stages (gametocytes). Soon after being taken up by a mosquito, gametocytes rapidly produce gametes and, once mated, they infect their vector and can be transmitted to new ...
Abdel-Wahab, Akim, Alano, Ali, Babiker, Babiker, Babiker, Babiker, Bell, Billingsley, Bonnet, Boudin, Bousema, Bousema, Bousema, Buckling, Buckling, Buckling, de Roode, Dixon, Drakeley, Drew, Dunyo, Dye, El-Sayed, Farnert, Farnert, Ferguson, Gaillard, Gardner, Gautret, Graves, Hamza A. Babiker, Hill, Huber, Jarvi, Jeffery, Kooij, Menegon, Mideo, Nassir, Nee, Niederwieser, Nwakanma, Okell, Osorio, Ouédraogo, Paganotti, Paul, Paul, Paul, Paul, Petra Schneider, Pichon, Pradel, Read, Reece, Reece, Robert, Sarah E. Reece, Schall, Schall, Schneider, Schneider, Schneider, Shekalaghe, Shekalaghe, Shutler, Shutler, Smith, Sokhna, Sowunmi, Talman, Talman, Targett, Trager, Vardo, Wargo, Wargo, Wargo, Werren, West   +81 more
core   +2 more sources

A case of visceral leishmaniasis mimicking connective tissue disease

Rheumatology &Autoimmunity, EarlyView.
Yucui Li, Hongxia Yang, Tingzi Zhao, Ke Xu, Liyun Zhang   +4 more
wiley   +1 more source

Development and Validation of In‐House Conventional and Multiplex PCR Methods for the Detection and Identification of Lophomonas spp.: An Innovative Approach

Journal of Clinical Laboratory Analysis, Volume 39, Issue 12, June 2025.
Sequence alignment of the SSU rRNA of the two Lophomonas species, L. blattarum and L. striata. The red rectangle highlights the position of the reverse universal primer; the yellow, the L. blattarum‐specific forward primer; and the green, the L. striata‐specific forward primer used in multiplex PCR.
Maryam Nakhaei, Mahdi Fakhar, Abouzar Bagheri, Hajar Ziaei Hezarjaribi, Saied Abediankenari, Ali Sharifpour, Maryam Ghasemi   +6 more
wiley   +1 more source

Lactylation: From Homeostasis to Pathological Implications and Therapeutic Strategies

MedComm, Volume 6, Issue 6, June 2025.
Lactylation, a novel post‐translational modification derived from lactate metabolism, plays a critical role in cellular homeostasis and disease pathogenesis. Under physiological conditions, lactylation regulates gene expression, immune responses, and metabolic adaptation. However, dysregulated lactylation is implicated in various pathological processes,
Xi Chen, Yixiao Yuan, Fan Zhou, Lihua Li, Jun Pu, Yong Zeng, Xiulin Jiang   +6 more
wiley   +1 more source

Selection of binding targets in parasites using phage-display and aptamer libraries in vivo and in vitro [PDF]

, 2013
Parasite infections are largely dependent on interactions between pathogen and different host cell populations to guarantee a successful infectious process.
Alves, Maria Julia Manso, Colli, Walter, Tonelli, Renata Rosito   +2 more
core   +2 more sources

Intranasal vaccine from whole Leishmania donovani antigens provides protection and induces specific immune response against visceral leishmaniasis.

PLoS Neglected Tropical Diseases, 2021
Visceral leishmaniasis is a protozoan disease associated with high fatality rate in developing countries. Although the drug pipeline is constantly improving, available treatments are costly and live-threatening side effects are not uncommon. Moreover, an
Doumet Georges Helou, Aurélie Mauras, François Fasquelle, Juliane Sousa Lanza, Philippe M Loiseau, Didier Betbeder, Sandrine Cojean   +6 more
doaj   +1 more source